Advances in COPD II

Dear Colleagues,

Chronic obstructive pulmonary disease (COPD) is the third world leading cause of death. COPD is a complex disease presenting airflow obstruction alongside systemic conditions associated with inflammation and alterations in repair mechanisms. Among the risk factors, the inhalation of cigarette smoke and other harmful particles is the most prominent. Synergistic effects such as excess body fat, poor nutrition, respiratory infections during childhood, and poor housing conditions are associated with a higher prevalence of COPD. Comorbid disease potentiates the morbidity of COPD, leading to hospitalizations, mortality, and healthcare costs. The complexity and heterogeneity of this disease hinder the development of novel treatments. New data on possible basic mechanisms at the cellular and molecular level addressing the complexity and heterogeneity of lung and systemic COPD will support advances in health treatment and care. 

This Special Issue aims to summarize advances in the COPD area of research, including studies on epidemiology, diagnostics tools, the basic mechanisms in COPD, pharmacotherapy, rehabilitation, and skeletal muscle comorbidity and emerging therapies. 

We look forward to your contribution

Dr. Davina C. M. Simoes
Dr. Esther Barreiro
Guest Editors

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