Cellular Senescence and Transformation: Unraveling the Biological Links Between Aging and Cancer
Special Issue Editors
Interests: embryo development; genome editing; epigenetics; cancer; stem cells; somatic cell nuclear transfer; oxidative stress; pig; natural products; phase separation
Special Issues, Collections and Topics in MDPI journals
Interests: aging; neurodegenerative diseases; α-synuclein aggregation; phase seperation; non-membraneless organelles; genome editing; animal model
Interests: tyrosine phosphatase; autoimmune diseases; protein interactions; TCR signaling pathway; T cell development; T cell activation; T cell differentiation; inflammation; membrane transport; nuclear transport; cancer
Special Issue Information
Dear Colleagues,
Aging and cancer, two complex biological processes, share an intimate and paradoxical relationship. While advanced age is the single greatest risk factor for most cancers, the underlying cellular and molecular mechanisms driving this connection remain a central question in biomedical research. This interplay involves a delicate balance: hallmarks of aging, such as genomic instability, epigenetic alterations, and cellular senescence, can create a permissive environment for oncogenesis. Conversely, mechanisms that suppress cancer often overlap with those that promote aging.
In this Special Issue, original research articles, comprehensive reviews, communications, and systematic reviews are welcome. Research areas may include but are not limited to the following:
- Cellular senescence;
- Aging and cancer;
- Cellular reprogramming;
- Gene editing; Epigenetics;
- Cancer therapy;
- Oxidative stress;
- DNA damage response;
- Metabolism;
- Immune surveillance;
- Microenvironment;
- Protein aggregation.
We look forward to receiving your contributions.
Dr. Yongye Huang
Dr. Lin Yuan
Dr. Yang Yu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- aging
- cancer
- stem cells
- gene editing
- oncogene
- apoptosis
- targeted therapy
- epigenetics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
