Heme Biology in Health and Disease
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cells of the Cardiovascular System".
Deadline for manuscript submissions: closed (31 December 2024) | Viewed by 946
Special Issue Editors
Interests: nitric oxide; heme; cancer; inflammation; immune suppression; tryptophan metabolism
Special Issue Information
Dear Colleagues,
Heme is a complex of iron with protoporphyrin IX that is essential for the function of all aerobic cells. Heme serves as the prosthetic group of numerous hemeproteins (e.g., hemoglobin, myoglobin, cytochromes, guanylate cyclase, and nitric oxide synthase) and plays an important role in controlling protein synthesis and cell differentiation. Cellular heme levels are tightly controlled; this is achieved by a fine balance between heme biosynthesis and catabolism by the enzyme heme oxygenase. Due to its immense importance in biology, heme can be rightly called the cornerstone of aerobic life on Earth and has been extensively studied over the years, leading to groundbreaking discoveries and continuing to be widely studied all over. New discoveries related to heme, hemeproteins, and heme synthesis and breakdown inside living systems continue, which makes this Special Issue very important and relevant in today’s scientific community, focusing its articles and reviews on heme, the basis of aerobic life on Earth.
Dr. Pranjal Biswas
Dr. Yue Dai
Guest Editors
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Keywords
- heme
- hemeproteins
- heme synthesis
- heme breakdown
- iron-protoporphyrin IX
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