The Role Glial Cells in Neurodegenerative Disorders

Dear Colleagues,

Glial cells, like microglia, astrocytes, and oligodendrocytes, constitute a large percentage of the central nervous system, while the activation of these cells plays a key role in neurological disorders, including stroke, trauma, neurodegeneration, infection, and autoimmunity, and their interactions are an emerging area of importance. Glial-mediated enhanced neurodegeneration can be caused by many glia-released factors, including chemokines, cytokines, growth factors, neurotransmitters, and extracellular vesicles, that can affect neuronal networks and function. The role of glial cells in neurodegeneration will not only enhance our knowledge in glia–neuron crosstalk but also target glial cells to develop therapeutics for neurodegeneration. Thus, this Special Issue will focus on the roles of different types of glial cells and their mechanisms for varied types of neurological disorders and the translational development of glia-directed therapeutics for the future. 

Dr. Susmita Sil
Guest Editor

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