Cutaneous Regeneration and Tissue Engineering: From Hair Follicle Regeneration to Skin Restoration

Dear Colleagues,

The regeneration of skin and its appendages, including hair follicles, sebaceous glands, and sweat glands, remains a central challenge in both dermatology and regenerative medicine. Treating clinical conditions such as alopecia, chronic ulcers, and extensive burns requires therapies that can restore not only the skin barrier but also its complex structure and function. Recent progress in regenerative biology and tissue engineering has introduced a variety of strategies to address this challenge. These include engineered skin constructs incorporating biomaterial scaffolds, organoid models that recapitulate skin development, and 3D skin equivalents composed of multiple cell types and vascular networks. These approaches are reshaping our understanding of how functional skin tissue can be reconstructed.

For this Special Issue, “Cutaneous Regeneration and Tissue Engineering: From Hair Follicle Regeneration to Skin Restoration”, we welcome original research articles and review papers covering broad approaches to skin regeneration. Studies are invited on fundamental mechanisms of skin and hair follicle regeneration, wound healing models, scaffold and biomaterial design, noncellular regenerative therapies such as exosomes or growth factors, and translational or preclinical applications. Submissions from researchers working on appendage regeneration, skin bioengineering, wound repair dynamics, or clinical strategies for alopecia and chronic wounds are highly encouraged. This Special Issue will bring together interdisciplinary contributions that advance the restoration of fully functional skin in both experimental and clinical contexts.

Dr. Soung-Hoon Lee
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.