Recent Developments in the Role of Enteroendocrine Cells in Gastrointestinal and Non-gastrointestinal Disorders

Dear Colleagues,

Enteroendocrine cells are a specialized type of cells that line the gastrointestinal tract. They contain specialized microvilli that can sense luminal contents such as micronutrients, microbiota, and short-chain fatty acids, and secrete gut hormones to control the functions of the gastrointestinal tract. These gut hormones affect other organs, and are thus used as drugs for the treatment of diseases outside of the gastrointestinal tract.

Research during the last decade has found that enteroendocrine cells play an important role in several gastrointestinal disorders, such as irritable bowel syndrome and microscopic colitis, as well as in non-gastrointestinal disorders such as diabetes, obesity, and Parkinson’s disease. Several methods have been used to investigate the disturbances of these cells, some of which include disturbances in cellular quantity, function, stem origin, and genetics.  

However, more research is needed to elaborate the role of these specialized cells in gastrointestinal and non-gastrointestinal disorders. In this Special Issue, we aim to highlight such research. We would like to welcome all researchers to submit their articles to this Special Issue concerning recent developments in the role of enteroendocrine cells in gastrointestinal and non-gastrointestinal disorders.

Dr. Tarek Mazzawi
Prof. Dr. Trygve Hausken
Guest Editors

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