Epigenetic Mechanisms and Aging: Model Organism Drosophila

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cell Nuclei: Function, Transport and Receptors".

Deadline for manuscript submissions: 15 November 2024 | Viewed by 65

Special Issue Editor

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Guest Editor
1. Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore
2. Division of Science, Yale-NUS College, Singapore 138527, Singapore
Interests: WNT; Drosophila; embryology; development; aging; metabolism; stem cells
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Special Issue Information

Dear Colleagues,

Cells have many pathways during the life of an organism: proliferate or die, differentiate or divide, etc. Cells also age and lose the ability to function. The fundamental question as to why this happens is complex, but it is clear that this process can be reversed in some instances. Drosophila melanogaster, or fruit fly, is a model organism with a long history of great contributions to science. As technology has progressed, the great genetic techniques have expanded to incorporating genome editing and many other advances. The short life cycle and conserved cellular processes make Drosophila an ideal model to investigate cellular behavior, especially for cellular pathways in vivo.

We hope that this Special Issue will bring together science utilizing the latest advancements and breakthroughs in cellular aging and behavior. We are looking for investigations and reviews on a wide-ranging list of topics, including signal transduction, cell migration, morphogenesis, homeostasis, polarity and adhesion, especially as these relate to adult tissues.

Dr. Nicholas Tolwinski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • drosophila melanogaster
  • model organism
  • cell biology
  • developmental biology
  • genetics
  • molecular biology
  • cell signaling
  • cellular differentiation
  • cell proliferation
  • cell cycle
  • cellular morphogenesis
  • cell-cell communication
  • stem cells
  • cell migration
  • apoptosis
  • cytoskeleton
  • cell adhesion
  • cellular metabolism
  • functional genomics
  • CRISPR/Cas9 in drosophila
  • omics technologies
  • disease models
  • drug discovery
  • regeneration
  • genetic screens
  • cellular stress responses

Published Papers

This special issue is now open for submission.
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