Molecular Mechanisms of Cell Division and Chromosome Segregation: What Can Go Wrong?

Dear Colleagues, 

Cell division consists of a series of tightly controlled events which lead a cell to segregate its genetic material, equally balanced into two daughter cells. The failure of cell division and the resulting generation of genetic instability (including both numerical and structural chromosomal abnormalities) lead to an unstable state, hence activating tumorigenic transformation. Cancer cells strive to elude the surveillance systems that monitor genome stability, such as those coordinated by the transcriptional regulator p53. Therefore, understanding how genetic stability is transmitted through cell division and how uncorrected mitotic errors can originate genetically unbalanced cells is of primary importance to cancer research.

Thus, this Special Issue entitled ‘Molecular Mechanisms of Cell Division and Chromosome Segregation: What Can Go Wrong?’ will discuss how the deregulation of molecular aspects of cell division can generate an unbalanced distribution of chromosomes and in turn contribute to cancer onset and progression. Both original research and review articles are welcome.

Prof. Dr. Patrizio Dimitri
Dr. Giovanni Messina
Guest Editors
Yuri Prozzillo 
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.