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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Emerging Biomarkers for Precision Oncology in Gastrointestinal Cancers

edited by

Alessandro Ottaiano

submission deadline 30 Apr 2027 | Viewed by 337 | Submission Open

Keywords: gastrointestinal cancers; precision oncology; cancer biomarkers; liquid biopsy; next-generation sequencing; predictive biomarkers; tumor microenvironment; cancer immunotherapy biomarkers; molecular profiling; translational oncology

(This special issue belongs to the Section Cancer Biomarkers)

Local, Systemic and Combined Therapy for Hepatocellular Carcinoma

edited by Xiaoqun Dong

submission deadline 30 Apr 2027 | Viewed by 313 | Submission Open

Keywords: hepatocellular carcinoma; immunotherapy; cell therapy; targeted therapy; local therapy; combination therapy; oncolytic virus; precision oncology; drug resistance; translational research

(This special issue belongs to the Section Cancer Therapy)

Advances in Surgery for Gynecologic Cancer

edited by

Emmanouil Kalampokas

submission deadline 30 Apr 2027 | Viewed by 297 | Submission Open

Keywords: sentinel lymph node mapping; cervical cancer; robotic-assisted laparoscopy; cytoreductive surgery; nerve-sparing techniques; image-guided surgery; enhanced recovery after surgery; molecular staging; individualized surgery; endometrial cancer

Decoding Glioblastoma: Mechanisms, Innovations, and Therapeutic Advancements

edited by

Frances Chow

, Jerica M. Lomax and Yoon Jae Choi

submission deadline 30 Apr 2027 | Viewed by 242 | Submission Open

Keywords: glioblastoma; tumor heterogeneity; resistance; glioma stem cells; multi-omics; molecular targeting; tumor microenvironment; immunotherapy; spatial transcriptomics; epigenetic regulation; metabolic reprogramming; liquid biopsy; radiomics; advanced imaging; nuclear medicine

Advances in Supportive Care in Radiation Oncology

edited by Lukas Käsmann

submission deadline 30 Apr 2027 | Viewed by 237 | Submission Open

Keywords: supportive care; radiation oncology; symptom management; patient-reported outcomes; radiation dermatitis; oral mucositis; cancer survivorship; integrative oncology; quality of life

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Epigenomic and Transcriptional Mechanisms in Cancer Progression and Therapy Response

edited by Benjamin L. Kidder

submission deadline 30 Apr 2027 | Viewed by 233 | Submission Open

Keywords: cancer progression; genetic mutations; epigenomic plasticity; tumor heterogeneity; gene regulatory networks; epigenomic mechanisms

(This special issue belongs to the Section Molecular Cancer Biology)

Digestive Tract Cancers: A State-of-the-Art Perspective on Epidemiology, Risk Factors, Molecular Mechanisms, Prevention, Diagnosis and Management

edited by Paraskevi A Farazi

submission deadline 30 Apr 2027 | Viewed by 220 | Submission Open

Keywords: colorectal; pancreatic; liver; biliary; esophageal; stomach cancers; epidemiology; risk factors; molecular mechanisms; prevention; diagnosis; treatment

Beyond Breast Cancer—Rehabilitation for Survivorship

edited by

Elisabeth Kenne Sarenmalm

and

Jenny Nyqvist-Streng

submission deadline 30 Apr 2027 | Viewed by 215 | Submission Open

Keywords: breast cancer; rehabilitation; person-centered: clinical follow-up; physiotherapy; psycho-social support; existential support; patient education and self-management

Innovations in Pathological and Clinical Research in Colorectal Cancer

edited by

Seiichi Shinji

and

Toshiyuki Ishiwata

submission deadline 30 Apr 2027 | Viewed by 197 | Submission Open

Keywords: colorectal cancer; clinicopathological prognostic biomarkers; pathology-guided therapeutic strategies

The Relationship Between Cancers Metabolism and Immunotherapy

edited by Suguru Saito

submission deadline 30 Apr 2027 | Viewed by 193 | Submission Open

Keywords: anti-tumor immunity; metabolism; immunotherapy; macrophages; T cells; exhaustion

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

The Roles of Endoscopies in Gastrointestinal Neoplasm

edited by

Hajime Isomoto

and Hideki Kobara

submission deadline 30 Apr 2027 | Viewed by 149 | Submission Open

Keywords: gastrointestinal cancer; image enhanced endoscopy; early cancer detection; endoscopic submucosal dissection (ESD); endoscopic resection; AI-assisted diagnosis; surveillance endoscopy

(This special issue belongs to the Section Methods and Technologies Development)

Melanoma Combination Therapy: New Horizons, Challenges and Clinical Breakthroughs

edited by Gino K. In, Sanjay Chandrasekaran and

Vincent T. Ma

submission deadline 30 Apr 2027 | Viewed by 148 | Submission Open

Keywords: advanced melanoma; combination checkpoint blockade; targeted therapy; peri-operative therapy; adoptive cellular therapy; intratumoral therapy; rare melanomas; abscopal effect

(This special issue belongs to the Section Cancer Therapy)

Modern Radiation Therapy on Refractory Cancer Treatment: Technological Innovations, New Paradigms, Personalized Medicine and Recent Clinical Advances

edited by

Hualin Zhang

submission deadline 30 Apr 2027 | Viewed by 117 | Submission Open

Keywords: adaptive therapy; personalized radiation therapy; refractory cancer; spatially fractionated radiation therapy; minibeam; microbeam; flash therapy

(This special issue belongs to the Section Cancer Therapy)

Advances in the Surgical Management of Pancreatic Cancer

edited by Richard Zheng and

Avinoam Nevler

submission deadline 30 Apr 2027 | Viewed by 96 | Submission Open

Keywords: pancreatic cancer; pancreatic surgery; pancreatectomy; PDAC; outcomes; minimally invasive surgery; enhanced recovery after surgery (ERAS)

(This special issue belongs to the Section Cancer Therapy)

Nanocarrier in Cancer Therapy

edited by

Koyeli Girigoswami

submission deadline 30 Apr 2027 | Viewed by 84 | Submission Open

Keywords: nanocarriers; cancer therapy; nanomedicine; targeted drug delivery; stimuli-responsive nanocarriers; tumor microenvironment; nanoparticles; theranostics; drug resistance; precision oncology

(This special issue belongs to the Section Methods and Technologies Development)

Emerging Imaging and Radiotherapy Techniques for CNS Tumors

edited by

Tugce Kutuk

and

Joshua D. Palmer

submission deadline 30 Apr 2027 | Viewed by 51 | Submission Open

Keywords: CNS tumors; neuro-oncology; advanced imaging; molecular imaging; MRI; PET imaging; stereotactic radiosurgery (SRS); adaptive radiotherapy; proton therapy; stereotactic body radiotherapy (SBRT)

(This special issue belongs to the Section Methods and Technologies Development)

The Role of Immune Checkpoint Inhibitors in Cancer Therapy

edited by

Min Zhou

submission deadline 30 Apr 2027 | Viewed by 51 | Submission Open

Keywords: immune checkpoint inhibitors; immune checkpoint blockade; PD-1/PD-L1; CTLA-4; LAG-3; bispecific antibodies; predictive biomarkers; immunotherapy resistance; combination immunotherapy

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Molecular Mechanisms and Tumor Heterogeneity in Osteosarcoma

edited by Le Thi Thanh Thuy and

Hidetomi Terai

submission deadline 30 Apr 2027 | Viewed by 50 | Submission Open

Keywords: osteosarcoma; tumor heterogeneity; single-cell RNA sequencing/tumor microenvironment; immune checkpoint proteins and circulating biomarkers; therapeutic targets and translational treatment

(This special issue belongs to the Section Molecular Cancer Biology)

Recent Advances in Pediatric Neuro-Oncology: Optimism for the Future

edited by James Rutka

submission deadline 30 Apr 2027 | Viewed by 17 | Submission Open

Keywords: neuro-oncology; neuroimaging; neurosurgery; molecular genetics; neuropathology; chemotherapy; radiation therapy; targeted therapy; immunotherapy

(This special issue belongs to the Section Pediatric Oncology)

Palliative and Supportive Care in Oncology: An Update (2nd Edition)

edited by

Marco Cesare Maltoni

, Romina Rossi,

Antonino Musolino

, Andrea Carlini and Lucia Angelini

submission deadline 30 Apr 2027 | Viewed by 7 | Submission Open

Keywords: palliative care; supportive care; quality of life; integrative medicine; palliative radiotherapy; end of life care; cancer care; quality of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Interventional Cancer Pain Management: Current Evidence, Unresolved Questions, and Future Directions

edited by

Giustino Varrassi

and

Matteo Luigi Giuseppe Leoni

submission deadline 30 Apr 2027 | Viewed by 6 | Submission Open

Keywords: cancer pain; pain management; neoplasm metastasis; analgesia; neurosurgical procedures; palliative care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

The Role of Physical Activity in Cancer Prevention, Treatment and Rehabilitation

edited by

Iwona Malicka

and

Aleksandra Kowaluk

submission deadline 1 May 2027 | Viewed by 223 | Submission Open

Keywords: cancer; hematooncology; adults; children; physical activity; exercise; interventions; supportive care; prevention; recovery; quality of life

Gynecological Oncology and Robotic Surgery

edited by

Giuseppe Vizzielli

and

Giulia Pellecchia

submission deadline 10 May 2027 | Viewed by 366 | Submission Open

Keywords: gynecologic oncology; robotic-assisted surgery; minimally invasive surgery; artificial intelligence; surgical innovation; multidisciplinary care

(This special issue belongs to the Section Methods and Technologies Development)

The Clinical Trials and Management of Acute Myeloid Leukemia: 2nd Edition

edited by

Margaret T. Kasner

submission deadline 14 May 2027 | 2 articles | Viewed by 7572 | Submission Open

Keywords: acute myeloid leukemia; clinical trials; translational research; targeted therapies; novel agents

(This special issue belongs to the Section Clinical Research in Cancer)

Clinical Applications of Advanced MRI Technologies for Cancers

edited by

Nicolò Cardobi

submission deadline 15 May 2027 | 2 articles | Viewed by 2665 | Submission Open

Keywords: advanced MRI techniques; multiparametric imaging; quantitative biomarkers; artificial intelligence; treatment response assessment; precision oncology; radiomics; cancer diagnosis; functional imaging; molecular imaging

(This special issue belongs to the Section Methods and Technologies Development)

Tumor Microenvironment of Gynecological Tumors

edited by

Zahid Pranjol

and

Dmitry Aleksandrovich Zinovkin

submission deadline 20 May 2027 | 4 articles | Viewed by 6143 | Submission Open

Keywords: tumor microenvironment; gynecological cancers; immunomodulation; cancer-associated fibroblasts; angiogenesis; cancer-like stem cells; extracellular matrix; immune evasion; cell signaling; therapeutics

(This special issue belongs to the Section Tumor Microenvironment)

New Statistical and Machine Learning Methods for Cancer Research

edited by Anjishnu Banerjee

submission deadline 20 May 2027 | 2 articles | Viewed by 2383 | Submission Open

Keywords: statistical methods; machine learning; “Omics” research; adaptive clinical trials; drug development; personalized cancer therapies

(This special issue belongs to the Section Cancer Informatics and Big Data)

Surgical Management of Colorectal and Anal Cancers

edited by Gyung-mo Son

submission deadline 21 May 2027 | Viewed by 14 | Submission Open

Keywords: colorectal cancer; anal cancer; surgical treatment; management

(This special issue belongs to the Section Cancer Therapy)

Clinical Studies of Colorectal Cancer Surgery

edited by

Konstantinos Perivoliotis

and Ioannis Baloyiannis

submission deadline 25 May 2027 | Viewed by 317 | Submission Open

Keywords: colon; rectal; cancer; clinical; trials; evidence; open; laparoscopic; robotic; surgery

(This special issue belongs to the Section Clinical Research in Cancer)

Novel Minimally Invasive Surgery for Urological Oncology: Techniques and Outcomes

edited by Grivas Nikolaos and Filippos Nikitakis

submission deadline 28 May 2027 | Viewed by 61 | Submission Open

Keywords: robot-assisted radical prostatectomy; laparoscopic partial nephrectomy; minimally invasive cystectomy; urinary continence recovery; oncological outcomes; Retzius-sparing surgery; intraoperative image guidance; surgical innovation in uro-oncology

Integrating Molecular and Conventional Diagnostics in Thyroid Nodule Management: Implications for Cancer Diagnosis and Treatment

edited by

Kennichi Kakudo

and Yanhua Bai

submission deadline 30 May 2027 | 3 articles | Viewed by 2129 | Submission Open

Keywords: thyroid carcinoma; low-risk neoplasm; indeterminate thyroid nodule; molecular testing; ultrasound; FNA cytology; integrated risk stratification; multidisciplinary team discussion; active surveillance; conservative management

Research Progress in Artificial Intelligence of Radiation Oncology: Diagnosis and Therapy

edited by

Abadh Kishore Chaurasia

submission deadline 30 May 2027 | Viewed by 269 | Submission Open

Keywords: artificial intelligence; radiation oncology; digital pathology; biomarker prediction; outcome prediction; vision transformer; foundation model

(This special issue belongs to the Section Methods and Technologies Development)

Drug Resistance Mechanisms and Tumor Microenvironment in Upper Gastrointestinal Cancers

edited by

Zheng Chen

and Heng Lu

submission deadline 31 May 2027 | 2 articles | Viewed by 2661 | Submission Open

Keywords: drug resistance; tumor microenvironment; gastric cancer; esophageal cancer; immunotherapy; targeted therapy; biomarkers; precision medicine

(This special issue belongs to the Section Tumor Microenvironment)

Cancer After Kidney Transplant

edited by Sławomir Lizakowski

submission deadline 31 May 2027 | 2 articles | Viewed by 2155 | Submission Open

Keywords: immunosuppression; virus-associated cancer; skin cancer; graft survival; kidney transplantation; post-transplantation lymphoproliferative disorder

(This special issue belongs to the Section Transplant Oncology)

Psychological Factors and Cancer Survivorship

edited by

Deidre B. Pereira

and Ashley P. Ghiaseddin

submission deadline 31 May 2027 | 2 articles | Viewed by 1485 | Submission Open

Keywords: psycho-oncology; distress; distress management; biobehavior markers and mechanisms; quality of life outcomes; treatment outcomes; survival outcomes

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Cancer Drug Resistance: Mechanisms and Overcoming Strategies

edited by

Jessica M. Konen

submission deadline 31 May 2027 | 1 articles | Viewed by 1425 | Submission Open

Keywords: intrinsic resistance; acquired resistance; targeted therapy resistance; combination treatment strategies; immunotherapy resistance; tumor heterogeneity

(This special issue belongs to the Section Clinical Research in Cancer)

Strategies and Techniques in Diagnosing, Treating and Surveying Sarcoma

edited by H. Thomas Temple

submission deadline 31 May 2027 | 2 articles | Viewed by 1303 | Submission Open

Keywords: sarcoma; diagnosis; therapy; treatment; surgery; molecular; radiomics

Liver Transplantation Oncology: Innovations, Multidisciplinary Management, and Evolving Clinical Strategies

edited by

Sami Akbulut

and

Tevfik Tolga Şahin

submission deadline 31 May 2027 | Viewed by 381 | Submission Open

Keywords: liver transplantation; transplant oncology; hepatobiliary oncology; hepatocellular carcinoma; cholangiocarcinoma; gallbladder cancer; primary liver cancer; secondary liver malignancies; colorectal liver metastases; neuroendocrine liver metastases; surgical oncology; locoregional therapy; systemic therapy; bridging therapy; downstaging; tumor recurrence; cancer surveillance; precision oncology; cancer biomarkers; artificial intelligence; clinical prediction models; real-world evidence; comparative effectiveness research; multidisciplinary cancer care

(This special issue belongs to the Section Clinical Research in Cancer)

Radiation Therapy for Pediatric Cancers: Precision Techniques, Late Effects, and Survivorship Strategies

edited by

John T. Lucas, Jr.

and

Chincheng Chen

submission deadline 31 May 2027 | Viewed by 302 | Submission Open

Keywords: pediatric radiation therapy; pediatric proton therapy; adaptive radiation therapy; advances in treatment planning and delivery; boron neutron capture therapy; molecularly targeted radiation therapy; late effects and survivorship; neurocognitive preservation; radiation-induced secondary malignancies; radiobiology of developing tissues; intellectual changes; cognitive outcomes

(This special issue belongs to the Section Pediatric Oncology)

Transcription Factors and Their Involvement in Carcinogenesis

edited by

Richard Morgan

submission deadline 31 May 2027 | Viewed by 275 | Submission Open

Keywords: transcription factors; transcription; transcriptome biomarkers; personalized medicine

(This special issue belongs to the Section Molecular Cancer Biology)

Perspectives in Surgical Treatments of Gastrointestinal Cancer

edited by Jayesh Sagar

submission deadline 31 May 2027 | Viewed by 228 | Submission Open

Keywords: artificial intelligence; robotic surgery; GI surgery; colorectal cancer

(This special issue belongs to the Section Methods and Technologies Development)

The Next Decade of Proton Therapy: Emerging Technologies, Clinical Translation and Grand Challenges

edited by

Xiao Wang

and

Zhiyan Xiao

submission deadline 31 May 2027 | Viewed by 156 | Submission Open

Keywords: image-guided proton therapy; emerging technologies; adaptive proton therapy; proton arc therapy; FLASH proton therapy; artificial intelligence; LET and RBE; biological optimization and robust optimization; precision radiation oncology; grand challenges

(This special issue belongs to the Section Cancer Therapy)

Technology for Tumor Biomarker Detection

edited by Gourav Kumar

submission deadline 31 May 2027 | Viewed by 151 | Submission Open

Keywords: early cancer detection; molecular imaging probes; liquid biopsy assays; advanced biosensors; microfluidic devices

(This special issue belongs to the Section Methods and Technologies Development)

Artificial Intelligence in Cancer Screening and Diagnostic Imaging

edited by

Lin-Ching Chang

Huiru Zheng

and

Zhaohui Liang

submission deadline 31 May 2027 | Viewed by 130 | Submission Open

Keywords: artificial intelligence; cancer screening; cancer diagnosis; medical image analysis; deep learning; large language models; multimodal and vision-language models; radiomics; computer-aided detection and diagnosis; explainable AI; precision oncology; AI-guided therapy planning

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

The New Era of ctDNA-Guided Precision Oncology: Escalation, De-Escalation, and Treatment Adaptation Across Solid and Hematologic Malignancies

edited by

Jad Chahoud

submission deadline 31 May 2027 | Viewed by 123 | Submission Open

Keywords: ctDNA; circulating tumor DNA; minimal residual disease; molecular residual disease; precision oncology; treatment escalation; treatment de-escalation; adaptive therapy; liquid biopsy; real-world evidence

(This special issue belongs to the Section Cancer Therapy)

Novel Surgical Treatment Approaches in Advanced Gastrointestinal Neoplasms, 2nd Edition

edited by Agostino Maria De Rose and Francesco Santullo

submission deadline 31 May 2027 | Viewed by 63 | Submission Open

Keywords: advanced gastrointestinal neoplasms; colon cancer; cytoreductive surgery; gastric cancer; liver metastases; peritoneal metastases; HIPEC (hyperthermic intraperitoneal chemotherapy); PIPAC (pressurized intraperitoneal aerosol chemotherapy); pancreatic cancer

(This special issue belongs to the Section Cancer Therapy)

Recent Advances in Precision Oncology: From Biomarkers and Early Detection to Prevention and Therapy

edited by

Nelson Yee

submission deadline 31 May 2027 | Viewed by 45 | Submission Open

Keywords: artificial intelligence; biomarker; cancer screening; clinical trials; digital twins; early detection; liquid biopsy; machine learning; multi-omics; precision oncology; targeted therapies; molecular targets; screening

Obesity and Metabolic Syndrome in Cancers

edited by Tseng Chin-Hsiao

submission deadline 31 May 2027 | Viewed by 15 | Submission Open

Keywords: obesity; metabolic syndrom; cancer; diabetes mellitus; insulin resistance; antidiabetic drugs; metformin

Photodynamic Therapy (PDT) and Proton Therapy (PT) of Cancer

edited by

Kave Moloudi

submission deadline 31 May 2027 | Viewed by 15 | Submission Open

Keywords: photo-dynamic therapy; photosensitizers; particle therapy; cancer resistance; immune response

(This special issue belongs to the Section Cancer Therapy)

Evidence-Based Care for Managing Oncologic Emergencies in Patients with Cancer

edited by

Aiham Qdaisat

and

Sai-Ching Jim Yeung

submission deadline 1 Jun 2027 | 1 articles | Viewed by 1635 | Submission Open

Keywords: oncologic emergencies; cancer; urgent; infections; adverse events; thrombosis; febrile neutropenia; pain; spinal cord compression; goals of care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Displaying special issue 951-1000 on page 20 of 22.

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