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Innovations in Pathological and Clinical Research in Colorectal Cancer

A Special Issue of Cancers (ISSN 2072-6694).

Deadline for manuscript submissions: 31 October 2026 | Viewed by 169

Editors


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Guest Editor
Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan
Interests: gastroenterology; colorectal surgery; experimental pathology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo, Japan
Interests: gastroenterology; oncology; experimental pathology; cell culture

Special Issue Information

Dear Colleagues,

Colorectal cancer (CRC) remains one of the leading causes of cancer-related morbidity and mortality worldwide. While advances in surgical and systemic therapies have improved patient outcomes, pathological examination continues to play a central role in diagnosis, prognostic stratification, and therapeutic decision-making. In addition, increasing attention has been directed toward early detection strategies and precision medicine approaches based on molecular profiling.

This Special Issue aims to highlight recent advances and showcase cutting-edge research in the pathological evaluation of colorectal cancer (CRC), integrating both basic and clinical insights. We welcome original papers, review articles, and systematic reviews focusing on innovative histopathological techniques, immunohistochemical and molecular markers, digital pathology, and artificial intelligence-assisted image analysis. Contributions exploring molecular biomarkers, morphofunctional analysis of CRC in 3D culture models, liquid biopsy-based pathological assessment, and genetic or molecular diagnostics are particularly encouraged. We also invite studies addressing pathological correlates of treatment response, tumor microenvironment characterization, tumor heterogeneity, and translational research that bridges bench and bedside to improve diagnostic precision and patient outcomes.

We invite contributions that advance pathological precision in CRC management. Your work will enrich interdisciplinary dialog and guide clinical practice.

We look forward to receiving your valuable contributions to this Special Issue.

Dr. Seiichi Shinji
Dr. Toshiyuki Ishiwata
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • colorectal cancer
  • clinicopathological prognostic biomarkers
  • pathology-guided therapeutic strategies

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Published Papers

This special issue is now open for submission.
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