Updates on Liver Cancer Management
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".
Deadline for manuscript submissions: 1 October 2025 | Viewed by 1155
Special Issue Editor
Interests: liver resection; laparoscopic liver resection; hepatocellular carcinoma; liver metastasis; chemotherapy (neoadjuvant, induction); liver venoocclusive disease; anus neoplasms; intensity modulated radiation therapy; chemoradiotherapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Hepatocellular carcinoma (HCC) remains a significant global health burden due to its high incidence and mortality. Over the past few decades, significant progress has been achieved in the management of HCC, with advanced surgeries, including minimally invasive and robot-assisted procedures, liver transplantation, and local ablation therapy potentially offering a cure. Trans-arterial treatment techniques and radiation therapies are being developed further, while the recent introduction of immunotherapy opened a new systemic treatment landscape. The introduction of several classification system for HCC (such as BCLC), clearly defining patient groups and assigning reasonable treatment options, has standardized treatment. Currently, a comprehensive and multidisciplinary approach is crucial for the effective management of this disease.
On the other hand, intrahepatic cholangiocarcinoma (ICC) is the second most frequent primary liver cancer after HCC, showing increasing incidence and mortality. It originates from intrahepatic bile ducts and has a silent presentation, with a highly aggressive nature. Upon diagnosis, less than 40% of ICC are suitable for curative surgical therapy, which is, so far, the only curative treatment. Although there have been attempts at early diagnoses and providing patient-personalized treatment by molecular characterization, these aims are not easily achieved because of the heterogeneity of this tumor. However, recent progress has been made in the molecular characterization, surgical treatment, and management of this disease.
In this SI on “Updates on Liver Cancer Management” (including metastatic cancers), a comprehensive overview of the evolving management landscape and challenges to its improvements will be provided.
Prof. Dr. Zenichi Morise
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- laparoscopic liver resection
- minimally invasive liver resection
- deteriorated liver function
- anatomical resection
- preoperative simulation
- intraoperative navigation
- liver metastasis
- hepatocellular carcinoma biliary tract cancers
- robot-assisted liver resection
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
