Metabolomics and Integrated Multi-Omics in Health and Disease

Dear Colleagues,

Metabolomics and the integration of multi-omics have emerged as key platforms for the understanding of healthy status and the association of metabolic disturbances with diseases. Much progress has been made in the last decade to obtain accurate metabolic profiles, and it is now standard practice. Both nuclear magnetic resonance and mass spectrometry are effective tools that analyze the molecular composition of a sample. Nevertheless, challenges remain in multiple clinical and methodological areas. There are virtually no fields in medicine in which the correct approaches do not result in possible new biologic insights based on adequate designs, instrumentation, and methods and, in particular, software for correct interpretation and data mining. Applications are not limited to “classical” metabolic diseases but also have a wide range of uses in drug discovery, cancer, cardiovascular health, aging, immunology, epigenetics or microbiome. Finding compounds, derived from natural sources, with the ability to interfere in a disease state and promote health is currently a hot topic. More recent analysis has provided evidence that some of the metabolome variation observed across individuals may be directly encoded in the genome, which might be valuable in personalized medicine. Therefore, this Topical Collection of Biomolecules welcomes all submissions of manuscripts, original research, comprehensive reviews, personal opinion focused on the fields and methods outlined. The following keywords describe the immediate interest and expertise from the Editors.

Prof. Jorge Joven
Dr. Fernández-Arroyo Salvador
Dr. Anna Hernández-Aguilera
Dr. Nuria Canela
Collection Editors

Manuscript Submission Information

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