Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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From Molecular Mechanisms to Therapeutics: Multidisciplinary Advances in Gene Expression Research
edited by Cristina Maracci
submission deadline 31 Aug 2026 | Viewed by 47 | Submission Open
Keywords: gene regulation; drug design; computational biology; AI modeling; protein synthesis; gene regulatory network; transcription; post-transcriptional regulation; molecular biology
(This special issue belongs to the Section Molecular Genetics)
State-of-the-Art of Myology: 3rd Edition submission deadline 31 Aug 2026 | Viewed by 44 | Submission Open
Keywords: embryonic myogenesis; adult myogenesis; exercise-induced muscle injury; muscular dystrophies and muscle diseases; sarcopenia; cachexia; rhabdomyosarcoma; muscle biophysics
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms of Antimicrobial Activity and Resistance in Pathogens
edited by
submission deadline 31 Aug 2026 | Viewed by 29 | Submission Open
Keywords: MDR profile in fungi; anti-fungal strategies; drug– target interactions; nanotechnology in antimicrobials; quorum-sensing molecular interactions; biofilm
(This special issue belongs to the Section Molecular Biology)
Physiological Responses and Biomolecular Adaptations to Environmental and Biotic Stress in Aquatic Species
edited by
submission deadline 31 Aug 2026 | Viewed by 1 | Submission Open
Keywords: aquaculture; fish pathogens; fish welfare; health protection
(This special issue belongs to the Section Molecular Biology)
Molecular Mechanisms and Microenvironmental Regulation in Bone-Related Diseases and Muscle Atrophy
edited by Haitao Wang
submission deadline 1 Sep 2026 | Viewed by 101 | Submission Open
Keywords: bone diseases; muscle atrophy; osteoporosis; osteoarthritis; osteosarcoma; sarcopenia; heterotopic ossification; molecular mechanisms; microenvironment; therapeutic targets
(This special issue belongs to the Section Molecular Medicine)
The Heme Oxygenase/Biliverdin Reductase System in Human Health and Disease: New Molecular Insights and Therapeutic Targets
edited by Cesare Mancuso
submission deadline 1 Sep 2026 | Viewed by 43 | Submission Open
Keywords: Alzheimer’ s disease; bilirubin; cancer; carbon monoxide; cardiovascular diseases; cerebral malaria; diabetes mellitus; drug research and development; inflammation; Parkinson’ s disease
(This special issue belongs to the Section Molecular Medicine)
Biotherapeutic Analysis: Precision Characterization and Quality Control
edited by
submission deadline 20 Sep 2026 | Viewed by 65 | Submission Open
Keywords: biotherapeutics; analytical characterization; quality control; mass spectrometry; cell therapy; gene therapy; biologics; process analytical technology; regulatory science
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Role of Lipids in Cellular Metabolism and Communication
edited by
submission deadline 30 Sep 2026 | Viewed by 114 | Submission Open
Keywords: sphingolipids; phospholipids; eicosanoids; steroids; extracellular vesicles; cancer; diabetes; obesity; atherosclerosis
(This special issue belongs to the Section Lipids)
Advances in Targeted At-211 Alpha Therapy
edited by Hsiaoju Sharon Lee and Yawen Li
submission deadline 30 Sep 2026 | Viewed by 101 | Submission Open
Keywords: Astatine-211; astatination; targeted alpha therapy; alpha radioimmunotherapy; radiotheranostics; radiopharmaceuticals
(This special issue belongs to the Section Chemical Biology)
Spatial and Single-Cell Phosphoproteomics: Emerging Methods and Applications
edited by Cinzia Franchin
submission deadline 30 Sep 2026 | Viewed by 70 | Submission Open
Keywords: phosphoproteomics; single-cell phosphoproteomics; cell signalling; spatial phosphoproteomics; phosphopeptides
(This special issue belongs to the Section Molecular Biology)
Deciphering Disease Progression Through Multi-Omics Integration
edited by Cinzia Franchin
submission deadline 30 Sep 2026 | Viewed by 63 | Submission Open
Keywords: multi-omics integration; systems biology; biomarkers; disease progression; precision medicine; computational modelling
(This special issue belongs to the Section Molecular Biology)
The Impact of Blood Pressure on Neurological Outcomes
edited by Phillip J. Tully
submission deadline 30 Sep 2026 | Viewed by 47 | Submission Open
Keywords: neurological disorders; neurodegenerative disorders; brain imaging; dementia; hypertension; blood pressure; cerebral blood flow
(This special issue belongs to the Section Molecular Medicine)
Feature Papers in 'Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates'
edited by
submission deadline 30 Sep 2026 | Viewed by 17 | Submission Open
Keywords: biomacromolecules; proteins; DNA; RNA; chromatin; epigenetics; gene regulation; genomics; proteomics; metabolomics; computational approaches; molecular biotechnology; molecular therapeutics
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
The Function of Stromal Cells in Gastrointestinal (GI) Diseases
edited by Li Chang
submission deadline 23 Oct 2026 | Viewed by 43 | Submission Open
Keywords: gastrointestinal (GI) diseases; intestinal stromal cells; intestinal homeostasis; cytokine; extracellular matrix; tissue repair
(This special issue belongs to the Section Molecular Medicine)
Molecular Research on Sarcoma: From Pathogenesis to Molecular Targets
edited by
submission deadline 30 Oct 2026 | Viewed by 120 | Submission Open
Keywords: sarcoma; molecular pathogenesis; genetic alterations; biomarkers; molecular targets; signal transduction
Computational Pharmacology: Advances in Computational Modeling of Drug–Receptor Interactions and Pharmacokinetics
edited by and
submission deadline 30 Oct 2026 | Viewed by 105 | Submission Open
Keywords: computational pharmacology; drug– receptor interactions; pharmacokinetics modeling; molecular dynamics simulations; molecular docking; QSAR analysis; ADME prediction; AI in drug design; machine learning for drug discovery; protein– ligand binding; bioactive peptide– protein interactions; drug– enzyme interactions; drug– nucleic acid interactions; protein– lipid interactions; peptoid-target interactions; therapeutic optimization; pharmacodynamic modeling
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Novel Molecular Targets for Beta Cell Regeneration and Diabetes Therapy
edited by Iraj Alipourfard
submission deadline 30 Oct 2026 | Viewed by 81 | Submission Open
Keywords: diabetes; pancreatic beta cells; regenerative therapy; molecular target
(This special issue belongs to the Section Molecular Medicine)
Multifunctional Enzymes and Proteins: New Insights into Structure and Function submission deadline 31 Oct 2026 | Viewed by 19 | Submission Open
Keywords: multifunctional enzymes; protein structure; protein function; catalytic activity; conformational dynamics; biochemistry; biophysics; drug discovery
(This special issue belongs to the Section Molecular Biology)
Feature Papers in Section Biological Factors, 2nd Edition
edited by
submission deadline 31 Oct 2026 | Submission Open
Keywords: neurotransmitters; cytokines; chemokines; hormones; connexins; androgen; estrogens; coagulation factors; hypoxia-inducible factors; transcription factors; signaling; receptors; interferon
(This special issue belongs to the Section Biological Factors)
Advances in Molecular Mechanisms and Predictive Biomarkers in Cancer Immunotherapy
edited by Fabrizio Nelli, and
submission deadline 30 Nov 2026 | Viewed by 39 | Submission Open
Keywords: immune checkpoint inhibitors; solid tumors; predictive biomarkers; resistance mechanisms; PD-1/PD-L1 pathway; efficacy; response; immune-related adverse events; real-world evidence
(This special issue belongs to the Section Molecular Biomarkers)
Molecular and Genetic Basis of Hormonal Signaling and Inter-Organ Crosstalk in Steatotic Liver Disease
edited by Karuna Rasineni and Sundararajan Mahalingam
submission deadline 30 Nov 2026 | Submission Open
Keywords: metabolic liver disease; organ crosstalk; hormones; gut– liver axis; adipose– liver axis; neuroendocrine control of liver function
(This special issue belongs to the Section Molecular Medicine)
Recent Molecular Research on Protein Structure and Function
edited by
submission deadline 15 Dec 2026 | 1 articles | Viewed by 1153 | Submission Open
Keywords: protein structure; protein function; molecular mechanisms; protein folding; structural biology
(This special issue belongs to the Section Molecular Biology)
Impact of Lifestyle Changes on Biomolecular Profiles Across the Lifespan submission deadline 30 Dec 2026 | Viewed by 42 | Submission Open
Keywords: lifestyle; microRNAs; disease
(This special issue belongs to the Section Chemical Biology)
Advances in Galectins
edited by Anu Paul and Diyoly Ayona
submission deadline 31 Dec 2026 | 2 articles | Viewed by 5651 | Submission Open
Keywords: galectins; carbohydrate-binding proteins; galectin– microbe
(This special issue belongs to the Section Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates)
Molecular, Cellular, and Blood Biomarkers in Diagnosis, Prognosis, Monitoring, and Treatment: 2nd Edition
edited by , Isabel Fort Gallifa and Xavier Gabaldó Barrios
submission deadline 31 Dec 2026 | 1 articles | Viewed by 256 | Submission Open
Keywords: biomarkers; infectious diseases; laboratory medicine; non-communicable diseases
(This special issue belongs to the Section Molecular Biology)
Molecular Insights into Quantum Biology
edited by Daniel R. Kattnig
submission deadline 31 Dec 2026 | Viewed by 123 | Submission Open
Keywords: quantum biology; molecular mechanisms; quantum coherence; quantum entanglement; magnetoreception; quantum cognition; photosynthetic energy transfer; biological qubits; quantum sensing; environment-assisted quantum effects
(This special issue belongs to the Section Molecular Biophysics: Structure, Dynamics, and Function)
Human ABC Transporters in Drug Disposition and Resistance: 50 Years of Progress and Future Perspectives
edited by
submission deadline 31 Dec 2026 | Viewed by 91 | Submission Open
Keywords: ABC transporters; drug disposition; drug resistance; pharmacokinetics; pharmacodynamics; pharmacogenetics; single nucleotide polymorphisms (SNPs)
(This special issue belongs to the Section Chemical Biology)
Cellular Regulation of Inflammatory Diseases
edited by
submission deadline 31 Dec 2026 | Viewed by 67 | Submission Open
Keywords: inflammatory diseases; inflammation; neutrophils; monocytes/macrophages; T cells; B cells; NK cells; dendritic cells
(This special issue belongs to the Section Cellular Biochemistry)
Biomolecules in Mycobacterial Pathogenesis, Host–Pathogen Interactions, and Antimicrobial and Therapeutic Approaches
edited by Cinzia Marianelli
submission deadline 31 Dec 2026 | Viewed by 67 | Submission Open
Keywords: mycobacterium; pathogenesis; host– pathogen interaction; antimicrobial action; therapeutic alternatives
(This special issue belongs to the Section Molecular Biology)
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