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Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gap Junctions and Connexins in Health and Disease, 2nd Edition

edited by

Béla Völgyi

and

Tamas Kovacs-Oller

submission deadline 20 Sep 2024 | 1 articles | Viewed by 2448 | Submission Open

Keywords: connexin; connexon; hemichannel; gap junction; electrical synapse; communication; bystander effect

(This special issue belongs to the Section Molecular Medicine)

Extracellular Vesicles as Biomarkers and Pathologic or Therapeutic Agents in Motor Neuron Diseases

edited by

Giambattista Bonanno

and

Marco Milanese

submission deadline 20 Sep 2024 | Viewed by 361 | Submission Open

(This special issue belongs to the Section Biological Factors)

The Role of Tau Protein in Neurodegenerative Diseases

edited by

Gernot Riedel

and Valeria Melis

submission deadline 20 Sep 2024 | Viewed by 329 | Submission Open

Keywords: tau biology; toxicity; utility as a biomarker and for diagnoses; cellular and molecular mechanisms of neuropathology; mechanisms of the aggregation and formation of filaments and tangles; all aspects of tau genetics; tau and the immune system; tau as a therapeutic target: current status and progress

(This special issue belongs to the Section Biomacromolecules: Proteins)

Novel Insights into the Role of Autoantibodies in Diseases—2nd Edition

edited by

Oscar J. Cordero

submission deadline 20 Sep 2024 | Viewed by 123 | Submission Open

Keywords: B cells; autoantibodies; peripheral blood; biomarkers; autoimmune diseases

(This special issue belongs to the Section Molecular Biomarkers)

Artificial Intelligence (AI) in Biomedicine

edited by

Le Nguyen Quoc Khanh

submission deadline 30 Sep 2024 | 10 articles | Viewed by 20841 | Submission Open

(This special issue belongs to the Section Bioinformatics and Systems Biology)

Neurological Disorders: From Molecular Mechanisms to Therapy Strategies

edited by

Oana Cioanca

Lucian Hritcu

and

Cornelia Mircea

submission deadline 30 Sep 2024 | 5 articles | Viewed by 20510 | Submission Open

Keywords: neurodegeneration; neuroprotection; novel therapies; natural molecules

(This special issue belongs to the Section Molecular Biology)

Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants

edited by

Daniela Grimm

submission deadline 30 Sep 2024 | 8 articles | Viewed by 16470 | Submission Open

Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems

(This special issue belongs to the Section Cellular Biochemistry)

Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives

edited by

Marion Korach-André

submission deadline 30 Sep 2024 | 7 articles | Viewed by 13651 | Submission Open

Keywords: diet; nutrients; obesity; inflammation; fat; glucose intolerance; insulin resistance; fatty liver disease; metabolic syndrome

(This special issue belongs to the Section Molecular Medicine)

Novel Molecules for Cancer Treatment (2nd Edition)

edited by

Javier Martínez Useros

submission deadline 30 Sep 2024 | 6 articles | Viewed by 13475 | Submission Open

Keywords: cancer; small molecules; antibody– drug-conjugated; tyrosine kinase inhibitors; target therapy; monoclonal antibodies; immunotherapy; natural compounds

(This special issue belongs to the Section Molecular Medicine)

Mitochondrial Quality Control in Aging and Neurodegeneration

edited by Sofie Lautrup

submission deadline 30 Sep 2024 | 5 articles | Viewed by 13142 | Submission Open

Keywords: mitochondria; quality control; mitochondrial biogenesis; mitochondrial dynamics; fission; fusion; mitophagy; mitochondrial degradation; cellular metabolism; aging; neurodegeneration; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease

(This special issue belongs to the Section Cellular Biochemistry)

Functional Peptides and Their Interactions

edited by

Mikhail Soloviev

and

Simon M. Cutting

submission deadline 30 Sep 2024 | 5 articles | Viewed by 8964 | Submission Open

Keywords: naturally occurring peptides; peptide engineering; peptide interactions; peptide self-assembly; peptide structure; small proteins; molecular therapeutics; biomaterials; biocatalysts

(This special issue belongs to the Section Molecular Structure and Dynamics)

Advances in β3-Adrenoceptor

edited by

Alessandro Pini

and

Luca Filippi

submission deadline 30 Sep 2024 | 4 articles | Viewed by 8225 | Submission Open

Keywords: β 3-adrenoceptor; cardiovascular diseases; cancer; prematurity; hypoxia/hyperoxia; neurodegenerative diseases; retinopathy

Novel Insights into Autoimmune/Autoinflammatory Skin Diseases

edited by

Angelo Valerio Marzano

Sergio Crovella

and

Chiara Moltrasio

submission deadline 30 Sep 2024 | 5 articles | Viewed by 6732 | Submission Open

Keywords: autoimmune/autoinflammatory skin diseases; omics; bioinformatics; pathogenesis; tailored medicine

(This special issue belongs to the Section Molecular Medicine)

Cellular and Molecular Mechanisms of Endometriosis

edited by

Luciana Bordin

, Alessandra Andrisani and Chiara Sabbadin

submission deadline 30 Sep 2024 | 4 articles | Viewed by 6731 | Submission Open

Keywords: endocrine dysfunction in endometriosis; glycosylphosphatidylinositols (GPIs) and GPI-anchored proteins; oxidative stress markers (glutathione; carbonic anhydrase; etc.); endometriosis and deep endometriosis; endometriosis-related immune system

(This special issue belongs to the Section Molecular Biology)

Interface of Aging and Biomaterials: 2nd Edition

edited by

Joshua T. Morgan

submission deadline 30 Sep 2024 | 3 articles | Viewed by 6341 | Submission Open

Keywords: aging; senescence; geroscience; biomolecules; biomaterials; biocompatibility; nanoparticles; hydrogels

(This special issue belongs to the Section Biological and Bio- Materials)

Biomarkers of Cardiovascular and Cerebrovascular Diseases

edited by

Ana Catarina Fonseca

submission deadline 30 Sep 2024 | 5 articles | Viewed by 4430 | Submission Open

Keywords: biomarkers; cardiovascular disease; cerebrovascular disease; cardiovascular therapy; diagnosis

(This special issue belongs to the Section Molecular Biomarkers)

Molecular Advances in Mechanism and Regulation of Lifespan and Aging

edited by Mark McCormick

submission deadline 30 Sep 2024 | 2 articles | Viewed by 4360 | Submission Open

Keywords: aging; lifespan; healthspan

(This special issue belongs to the Section Molecular Biology)

New Insights into Mechanisms and Therapeutics for Cardiovascular Disorders

edited by

Mohsin Saleet Jafri

Carola Yvette Förster

and Tarun W. Dasari

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2937 | Submission Open

Keywords: brain heart-axis; heart & stroke; stress-induced cardiomyopathy; cardiovascular disease

(This special issue belongs to the Section Molecular Medicine)

Molecular Profiling and Identification of Molecular Signatures Associated with Natural Products

edited by

Juei-Tang Cheng

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2645 | Submission Open

Keywords: natural product; molecular mechanisms; repurposed molecules; disease model; human health

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Programmed Cell Death (Apoptosis): Molecular Mechanisms and Implications for New Drug Discovery

edited by

Nunzia D’Onofrio

and

Elisa Martino

submission deadline 30 Sep 2024 | 1 articles | Viewed by 2471 | Submission Open

Keywords: programmed cell death; apoptosis; molecular aspects of apoptosis; apoptosis regulation; drug discovery; emerging therapeutic approaches

(This special issue belongs to the Section Cellular Biochemistry)

The Role of Cholinesterases in Alzheimer’s Disease and Other Neurodegenerative Disorders

edited by

Sultan Darvesh

submission deadline 30 Sep 2024 | 2 articles | Viewed by 2231 | Submission Open

Keywords: Alzheimer’ s disease; acetylcholinesterase; butyrylcholinesterase; enzymatic properties; non-enzymatic properties; neuroinflammation; drug development; neuroimaging

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Aptamer Therapeutics in Cancers: New Advances and Future Trends

edited by

Silvia Catuogno

and

Silvia Nuzzo

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1949 | Submission Open

Keywords: aptamers; cancer; targeted therapy; aptamer-based conjugates; aptamer-conjugated nanoparticles

(This special issue belongs to the Section Molecular Medicine)

Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders

edited by

Ana María Sánchez-Pérez

and

Sandra Sánchez-Sarasúa

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1523 | Submission Open

Keywords: insulin receptor substrates; microglia; degenerative diseases; psychiatric disorders; nutrition

(This special issue belongs to the Section Molecular Medicine)

Recent Trends in Kidney and Cardiovascular Diseases

edited by

Michele Provenzano

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1506 | Submission Open

Keywords: chronic kidney disease; cardiovascular risk; albuminuria; epidemiology; estimated glomerular filtration rate

(This special issue belongs to the Section Molecular Medicine)

The Role of Modulating Intracellular Signaling in Immune System

edited by

Jian Song

submission deadline 30 Sep 2024 | 1 articles | Viewed by 1001 | Submission Open

Keywords: signaling pathway; inflammation; autoimmune disease; treatment

(This special issue belongs to the Section Molecular Biology)

New Insights into the Membranes of Anoxygenic Phototrophic Bacteria

edited by

Robert A. Niederman

submission deadline 30 Sep 2024 | 1 articles | Viewed by 868 | Submission Open

Keywords: anoxygenic phototrophs; light harvesting; membrane dynamics; molecular evolution; reaction centers

(This special issue belongs to the Section Molecular Structure and Dynamics)

Genetic and Structural Analyses of SARS-CoV-2 and Its Variants

edited by

Stefano Pascarella

submission deadline 30 Sep 2024 | 1 articles | Viewed by 683 | Submission Open

Keywords: SARS-CoV-2 variants; protein variants; protein structure; virus evolution; mutations; structural bioinformatics; molecular phylogenesis; host– pathogen molecular interactions; molecular immunology; drug discovery

(This special issue belongs to the Section Molecular Structure and Dynamics)

Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples, Volume II

edited by

Maroula Kokotou

Petros Tarantilis

and

Christos Pappas

submission deadline 30 Sep 2024 | 1 articles | Viewed by 635 | Submission Open

Keywords: bioactive food ingredients (primary and secondary metabolites); secondary metabolites— natural products liquid chromatography-mass spectrometry; Fourier transform infrared (FTIR) and Raman spectroscopic analysis; gas chromatography-mass spectrometry; high-resolution mass spectrometry; lipids— amino acids— carbohydrates; polyphenols– terpenes

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Rare Diseases: From Molecular Pathways to Therapeutic Strategies 2.0

edited by

Saida Ortolano

submission deadline 30 Sep 2024 | Viewed by 614 | Submission Open

Keywords: adeno-associated virus ; gene editing ; metabolic diseases ; lysosomal disorders ; CRISPR ; inborn errors of metabolism ; neuromuscular disease

(This special issue belongs to the Section Molecular Medicine)

Insights into the Oral Microbiome and Its Modulation

edited by

Thuy Do

Dongmei Deng

and

Nailê Damé-Teixeira

submission deadline 30 Sep 2024 | Viewed by 513 | Submission Open

Keywords: oral microbiome; oral infectious diseases; systemic disease

(This special issue belongs to the Section Molecular Biology)

Glial Cross-Talk in Central Nervous System Health and Disease

edited by

Glória Queiroz

and

Clara Quintas

submission deadline 30 Sep 2024 | Viewed by 451 | Submission Open

Keywords: glial physiology; glial cross-talk in CNS homeostasis; glial cross-talk in neuroinflammation; glial cross-talk in CNS diseases

(This special issue belongs to the Section Molecular Biology)

Epigenetics in Parathyroid Tumors

edited by

Valentina Vaira

and

Sabrina Corbetta

submission deadline 30 Sep 2024 | Viewed by 333 | Submission Open

Keywords: parathyroid disorders; parathyroid adenomas; parathyroid cancers; epigenetics; LncRNAs; microRNAs; circular RNAs; DNA methylation; DNA acetylation

(This special issue belongs to the Section Molecular Medicine)

Plant-Microbe-Insect Interactions

edited by

Jinjie Cui

and Xueke Gao

submission deadline 30 Sep 2024 | Viewed by 258 | Submission Open

Keywords: plant– microbe– insect interactions; plant defense; insects; pest control; microbiology

(This special issue belongs to the Section Cellular Biochemistry)

Gene Mutations in Retinal Dystrophies

edited by Benedetto Falsini and

Emiliano Giardina

submission deadline 30 Sep 2024 | Viewed by 257 | Submission Open

Keywords: genes; retina; inherited retinal dystrophies; phenotype

Redox Balance and Proteostasis Surveillance in Neurodegenerative Disorders

edited by

Fabio Di Domenico

and

Antonella Tramutola

submission deadline 30 Sep 2024 | Viewed by 230 | Submission Open

Keywords: redox homeostasis; oxidative stress; antioxidant response; proteostasis; protein folding; protein oxidation; unfolded protein response; ubiquitin proteosome system; autophagy; neurodegeneration

(This special issue belongs to the Section Molecular Medicine)

Advanced Organometallic Syntheses for Biomedical Applications

edited by Bala Krishna Moku

submission deadline 30 Sep 2024 | Viewed by 219 | Submission Open

Keywords: advanced organometallic syntheses; biomedical applications; drug discovery; disease treatment; imaging; targeted therapy

(This special issue belongs to the Section Synthetic Biology and Bioengineering)

Biomolecules in Forensic Molecular Genetics

edited by

Erin K. Hanson

submission deadline 30 Sep 2024 | Viewed by 183 | Submission Open

Keywords: forensic; DNA; RNA; protein; mtDNA; epigenetics; microbiome

(This special issue belongs to the Section Molecular Genetics)

Recent Advances in the Structural and Functional Properties of Glutamate Dehydrogenase

edited by

Ioannis Zaganas

submission deadline 30 Sep 2024 | Viewed by 181 | Submission Open

Keywords: glutamate dehydrogenase; GLUD1; GLUD2; structure-function relationships; neurodegenerative disorders

(This special issue belongs to the Section Enzymology)

New Insights and Potential Therapeutic Options in Leukemia Metabolism Research

edited by

Alessio Biagioni

submission deadline 30 Sep 2024 | Viewed by 170 | Submission Open

Keywords: acute myeloid leukemia (AML); chronic myeloid leukemia (CML); acute lymphocytic leukemia (ALL); chronic lymphocytic leukemia (CLL); tumor metabolism; metabolic rewiring

(This special issue belongs to the Section Molecular Medicine)

New Insights into Kidney Disease Development and Therapy Strategies

edited by

José I. López

and

Claudia Manini

submission deadline 1 Oct 2024 | 3 articles | Viewed by 3434 | Submission Open

(This special issue belongs to the Section Molecular Medicine)

Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders

edited by

Floriana Della Ragione

and Salvatore Fioriniello

submission deadline 1 Oct 2024 | Viewed by 236 | Submission Open

Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders

(This special issue belongs to the Section Molecular Medicine)

Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases

edited by

Antonio Ferreras

submission deadline 15 Oct 2024 | 6 articles | Viewed by 17697 | Submission Open

Keywords: retina; macula; macular edema; inflammatory mediators; optical coherence tomography; retinal imaging; biochemical marker; biomarker; pharmacological targeting

(This special issue belongs to the Section Molecular Medicine)

Muscular Dystrophy: From Molecular Basis to Therapies

edited by

Francesca Sciandra

and

Kinga I. Gawlik

submission deadline 15 Oct 2024 | 5 articles | Viewed by 16709 | Submission Open

Keywords: muscular dystrophies; muscle regeneration; extracellular matrix; satellite cells; therapeutic approaches; animal models; clinical trials

(This special issue belongs to the Section Molecular Biology)

Mechanisms and Kinetics of Interactions of Biomolecules at Interfaces: 2nd Edition

edited by

Monika Wasilewska

Aneta Michna

and

Maria Morga

submission deadline 15 Oct 2024 | 4 articles | Viewed by 7898 | Submission Open

Keywords: biomolecule adsorption; kinetics of biomolecule adsorption; mechanisms of biomolecule deposition; interactions of biomolecules; techniques for the detection of biomolecules at solid substrates; interactions of proteins with biomolecules/biopolymers; protein and biomolecule systems; protein and biomolecule complexes

(This special issue belongs to the Section Biological and Bio- Materials)

Antibiotic Resistance Mechanisms and Their Potential Solutions

edited by Sung-Pin Tseng,

Cheng Yen Kao

and

Tsung-Ying Yang

submission deadline 15 Oct 2024 | 3 articles | Viewed by 5573 | Submission Open

Keywords: antibiotic resistance; antimicrobial development; molecular mechanism; priority for antibiotics; newly therapeutic approach

(This special issue belongs to the Section Molecular Biology)

TRP Channels in Cardiovascular and Inflammatory Disease

edited by

Susan D. Brain

and Soraia Katia Pereira Costa

submission deadline 15 Oct 2024 | 3 articles | Viewed by 4792 | Submission Open

(This special issue belongs to the Section Molecular Medicine)

New Insights into Cardiovascular Immunology

edited by Susanne Sattler, Pilar Martín and Stephen Malin

submission deadline 15 Oct 2024 | 1 articles | Viewed by 2547 | Submission Open

Keywords: inflammation; autoimmunity; atherosclerosis; myocarditis; heart failure

(This special issue belongs to the Section Molecular Medicine)

Role of Neuroactive Steroids in Health and Disease: 2nd Edition

edited by

Roberto Cosimo Melcangi

submission deadline 15 Oct 2024 | 3 articles | Viewed by 1654 | Submission Open

Keywords: neurosteroids; neurodegenerative disorders; psychiatric disorders; physiological effects

(This special issue belongs to the Section Molecular Biology)

Advances in Nano-Based Drug Delivery: Unveiling the Next Frontier

edited by

Yuping Bao

and

Jessica M. Larsen

submission deadline 15 Oct 2024 | 1 articles | Viewed by 1611 | Submission Open

Keywords: targeted drug delivery; smart nanoformulation; controlled drug release; biocompatible nanocarriers; extracellular vesicles; immunotherapy

(This special issue belongs to the Section Biological and Bio- Materials)

Molecular and Cell Biology in Endometriosis and Endometrial Cancer: 2nd Edition

edited by

Jacqueline F. Donoghue

submission deadline 15 Oct 2024 | 1 articles | Viewed by 846 | Submission Open

Keywords: endometriosis; endometrial cancer; ovarian cancer; molecular basis of endometriosis and endometrial cancer; single cell transcriptomics; spatial transcriptomics; multiomics; genomics; proteomics; epigenomics; metabolomics

(This special issue belongs to the Section Molecular Biology)

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