Special Issues

Biomolecules runs special issues to create collections of papers on specific topics. The aim is to build a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors who are experts in the subject and oversee the editorial process for papers. Papers published in a Special Issue will be collected together on a dedicated page of the journal website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Zinc in Health and Disease Conditions
edited by
submission deadline 15 May 2022 | 1 articles | Viewed by 612
Keywords: zinc; physiology; disease; regulation/modulation; function; pathology
(This special issue belongs to the Section Molecular Medicine)
Physiological Cell Culture submission deadline 15 May 2022 | Viewed by 194
(This special issue belongs to the Section Cellular Biochemistry)
Biomolecules in Development and Diseases of Urogenital System submission deadline 15 May 2022 | 4 articles | Viewed by 4468
Keywords: development; disease; urogenital system; morphology; biomolecules
(This special issue belongs to the Section Cellular Biochemistry)
State-of-the-Art in Antibiotics Resistance
edited by
submission deadline 15 May 2022 | Viewed by 466
Keywords: antibiotic resistance; antimicrobial resistance; multidrug resistance; extreme drug resistance; drug tolerance; bacterial infections; antibacterial treatment; antibiotic treatment strategy; infection control; resistome
(This special issue belongs to the Section Cellular Biochemistry)
Protein Modeling and Simulation: Selected articles from the Computational Structural Bioinformatics Workshop 2021 submission deadline 15 May 2022 | 1 articles | Viewed by 1108
Keywords: protein structure prediction; molecular simulation; computational biology; machine learning for protein modeling
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Postprandial Metabolism and Cardiovascular Risk
edited by Maryse Guérin
submission deadline 15 May 2022 | Viewed by 368
Keywords: Triglyceride rich lipoproteins; Atherosclerosis; Metabolic disorders; Genetics; Therapy; Diet; Liver; Intestine
(This special issue belongs to the Section Molecular Medicine)
Allosteric Regulation in Ubiquitin Proteasome System submission deadline 15 May 2022 | 2 articles | Viewed by 2453
Keywords: proteasome; ubiquitin proteasome system; allostery; allosteric regulators; proteostasis
(This special issue belongs to the Section Cellular Biochemistry)
Risk Prediction Tools and Biomarkers in Gynaecological Cancer
edited by and Iztok Takač
submission deadline 20 May 2022 | 3 articles | Viewed by 2992
Keywords: Gynaecological cancer; Biomarkers; Precision medicine; Risk prediction
(This special issue belongs to the Section Molecular Biomarkers)
Microglia in Neurodegeneration 2.0
edited by
submission deadline 20 May 2022 | Viewed by 104
Keywords: neuron– microglia communication systems; released molecules and exosomes; microglial phenotypes; molecular and epigenetic mechanisms; drug design
The Role of Angiotensin in Cardiovascular Disease
edited by Rosario Scalia and Tatsuo Kawai
submission deadline 20 May 2022 | 1 articles | Viewed by 1487
Keywords: Angiotensin II; RAAS; Cardiovascular diseases; AT1
(This special issue belongs to the Section Biological Factors)
New Insights into Myeloproliferative Neoplasms (MPNs)
edited by
submission deadline 20 May 2022 | Viewed by 201
Keywords: targeted inhibition; multisystem disease; clonal evolution; symptom control
(This special issue belongs to the Section Molecular Biology)
Potential Mechanism of Natural-Based Biomolecules for Disease Treatment
edited by
submission deadline 22 May 2022 | 7 articles | Viewed by 6527
Keywords: antibody therapy; peptide/protein drug; natural toxins; targeted therapy; immunotherapy; combinatorial treatment; mode of action
(This special issue belongs to the Section Natural and Bio-inspired Molecules)
Molecular Phase Transitions in Physiology and Pathology: Freezing and Precipitation in Biology submission deadline 25 May 2022 | 1 articles | Viewed by 766
Keywords: phase transitions; proteins; membranes; freezing; precipitation; liquid– liquid phase transition; liquid– gel phase transition
(This special issue belongs to the Section Biological Factors)
Prostate Cancer: From Models to Molecular Mechanisms and Precision Medicine
edited by
submission deadline 31 May 2022 | 6 articles | Viewed by 6242
Keywords: Prostate cancer; Models of disease; Cell signaling; Molecular mechanisms; Therapeutic resistance; Translational research; Precision medicine; Genetic drivers
(This special issue belongs to the Section Molecular Medicine)
In Silico Drug Design and Discovery: Big Data for Small Molecule Design submission deadline 31 May 2022 | 2 articles | Viewed by 2166
Keywords: drug discovery; molecular modeling; medicinal chemistry; chemoinformatics; data mining; machine learning
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Translational Biomarkers in Addictive Disorders
edited by , María S. García Gutiérrez and
submission deadline 31 May 2022 | 6 articles | Viewed by 5183
Keywords: addiction; biomarker; translational; diagnosis; therapy
(This special issue belongs to the Section Molecular Medicine)
Translational Approaches for the Detection and Treatment of Malaria
edited by Christiaan van Ooij
submission deadline 31 May 2022 | 1 articles | Viewed by 865
Keywords: Malaria; Antimalarial drug development; Rapid Diagnostic Testing; Plasmodium
(This special issue belongs to the Section Molecular Medicine)
Advances in Basic and Clinical Periodontal Research
edited by
submission deadline 31 May 2022 | 5 articles | Viewed by 4951
Keywords: Periodontal disease; Periodontal regeneration; biomolecules; biomaterials; Soft and hard tissue regeneration
(This special issue belongs to the Section Molecular Medicine)
Regulation and Mechanisms of Plant Biomass Degrading Enzymes from Fungi
edited by , and Paul Daly
submission deadline 31 May 2022 | 1 articles | Viewed by 2028
Keywords: fungi; gene regulation; plant biomass; CAZyme production; molecular tools
(This special issue belongs to the Section Enzymology)
Gaseous Transmitters and Cardiovascular System
edited by Sona Cacanyiova, and Andrea Berenyiova
submission deadline 31 May 2022 | 4 articles | Viewed by 3814
Keywords: Gaseous transmitters; Nitric oxide; Hydrogen sulfide; Carbon monoxide; Cardiovascular system
Metal Binding Proteins 2022 submission deadline 31 May 2022 | 8 articles | Viewed by 5781
Keywords: metal ions; metal binding proteins; regulation; enzymes; structure; function
(This special issue belongs to the Section Cellular Biochemistry)
Common Mechanisms in Alzheimer’s Disease and Other Neurodegenerative Disorders submission deadline 31 May 2022 | 13 articles | Viewed by 8584
Keywords: protein aggregation; amyloid toxicity; neurodegeneration; neuropharmacology
(This special issue belongs to the Section Molecular Medicine)
Functional Peptides and Their Interactions: From Molecules to Systems
edited by
submission deadline 31 May 2022 | 1 articles | Viewed by 755
Keywords: Peptides; Functional peptides; Peptide–peptide interactions; Peptide–protein interactions; Peptide engineering; Native peptides; Therapeutic peptides; Peptidomics; Proteomics
New Insights into Proteases and Chaperones in Pathogenic Microorganisms
edited by and Silja Wessler
submission deadline 31 May 2022 | 4 articles | Viewed by 3245
Keywords: Protease; Chaperone; Virulence factor; Virulence determinant; Protein maturation; Folding and secretion; Pathogen dissemination; Nutrient acquisition; Degradation of extracellular matrix; Cell junction damage; Protease inhibitors; Antimicrobials
New Insights into Prion and Prion-Like Diseases submission deadline 31 May 2022 | Viewed by 125
Keywords: prions; prion-like proteins; neurodegeneration; synaptic dysfunction; aggregation; propagation; structure– function relationship
Hsp90 Structure, Mechanism and Disease submission deadline 31 May 2022 | 1 articles | Viewed by 914
Keywords: Hsp90; heat shock proteins; chaperone; structure; mechanism; regulation; disease; cancer; neurological disease; drug development
Advances in Mesenchymal Stem Cells
edited by
submission deadline 31 May 2022 | 4 articles | Viewed by 3496
Keywords: MSCs; Secretome; Exosomes or EVs; Functional genomics; Nanotechnology; Biomolecules
(This special issue belongs to the Section Cellular Biochemistry)
Mechanoadaptation of Cell Structures, Signaling Pathways and Molecules
edited by
submission deadline 31 May 2022 | 1 articles | Viewed by 857
Keywords: Mechanosensitive molecules; Mechanotransduction pathways; Genome mechanoadaptation; Organelles and forces; Lipids and mechanoadaptation; Metabolism and mechanoadaptation
(This special issue belongs to the Section Molecular Structure and Dynamics)
New Insights into Cytochrome P450s
edited by
submission deadline 31 May 2022 | 2 articles | Viewed by 1741
Keywords: cytochrome P450 (P450); cytochrome b5; NADPH-P450 oxidoreductase (CPR); heme; flavin; P450 structure; P450 catalytic activities; prokaryotic P450; eukaryotic P450; viral P450; drug metabolism; detoxification; plant secondary metabolisms; membrane protein– protein complex; AlphaFold; AlphaFold2; regulation of P450 transcription; catalytic cavities; substrate access channels; prediction of protein– protein complex; P450 interaction on P450– CPR complex; tripartite P450– CPR– cytochrome b5 complex
(This special issue belongs to the Section Chemical Biology)
Molecular and Cellular Mechanisms of Optic Neuropathies
edited by
submission deadline 31 May 2022 | 1 articles | Viewed by 650
Keywords: optic neuropathies; cellular and molecular mechanisms of RGCs and/or axonal damage and repair; optic nerve regeneration
(This special issue belongs to the Section Molecular Medicine)
Signaling Biomolecules in the Central Nervous System (CNS)—At the Nexus of Neuropsychiatric and Neurodegenerative Disorders submission deadline 31 May 2022 | 4 articles | Viewed by 3071
Keywords: mood and anxiety disorders; Parkinson’ s disease; mechanisms of neurodegeneration; neuroprotection and brain repair; animal models; neurotransmitters; G protein-coupled receptors (GPCR); protein kinases; receptor– (RTK) and non– receptor tyrosine kinases; trophic factors; neuroplasticity
(This special issue belongs to the Section Molecular Biology)
Unveiling Protein Functions, Dynamics and Interactions in Health and Disease Using Experimental and Theoretical Approaches
edited by , Cristina Maracci, Alice Romagnoli and Stefano Motta
submission deadline 31 May 2022 | 6 articles | Viewed by 6329
Keywords: Protein’ s structure and dynamics; Protein-protein interactions; Point mutations; Molecular biology; Molecular modelling; Molecular dynamics; Biochemistry; Bioinformatics; Protein-ligand interaction; Protein-nucleic acids interaction; Protein’ s conformational changes
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Neutrophil Extracellular Traps Formation and Role in Inflammatory Diseases submission deadline 1 Jun 2022 | Viewed by 64
Keywords: neutrophil extracellular traps; extracellular traps; inflammation; infection; autoimmunity
Novel Imaging Biomarkers for Brain PET Imaging
edited by , and Nadja Van Camp
submission deadline 1 Jun 2022 | Viewed by 119
Keywords: positron emission tomography; neuroscience; drug development; neurology; biomarkers
(This special issue belongs to the Section Molecular Biomarkers)
Novel Advancements in Targeting Proteostasis in Human Diseases
edited by Aeid Igbaria
submission deadline 1 Jun 2022 | Viewed by 197
Keywords: proteostasis; chaperones; protein folding; aging; cancer
Selenocysteine: Synthesis, Function, and Evolution of the 21st Amino Acid
edited by
submission deadline 1 Jun 2022 | Viewed by 352
Keywords: selenocysteine; selenium; recoding
(This special issue belongs to the Section Biomacromolecules: Proteins)
Molecular Mechanisms of Skeletal Muscle Atrophy
edited by Tatiana L. Nemirovskaya and
submission deadline 15 Jun 2022 | Viewed by 167
Keywords: skeletal muscle; atrophy; unloading; denervation; aging; tenotomy; gene expression; signaling pathways
Advanced Researches in G-Protein-Coupled Receptors (GPCRs) and Their Closely Related Functional Proteins
edited by
submission deadline 15 Jun 2022 | 1 articles | Viewed by 954
Keywords: G-protein-coupled receptors; beta-arrestins; G-protein-coupled kinases (GRKs); heterodimerized GPCRs; signal biased GPCR ligands
Advances in DNA Methylation
edited by
submission deadline 15 Jun 2022 | Viewed by 42
Keywords: DNA methylation; Epigenetics; Signature; epigenetic editing; machine learning.
Chemistry, Biosynthesis and Biological Activity of Natural Substances: A Themed Issue Dedicated to Professor Evidente
edited by Alexander V Kornienko
submission deadline 15 Jun 2022 | 1 articles | Viewed by 845
Keywords: natural products; drug discovery; structure elucidation; synthesis; biosynthesis
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Biochemical Bases of TRP Channel Functions submission deadline 15 Jun 2022 | Viewed by 64
Keywords: TRP channels; TRP structure; TRP functional properties; TRP structure– function relationship; TRPs in pathophysiology
(This special issue belongs to the Section Cellular Biochemistry)
Intracerebral Hemorrhage: Advances in Preclinical Studies submission deadline 15 Jun 2022 | 6 articles | Viewed by 4519
Keywords: Neuroinflammation; Oxidative stress; Neurodegeneration; Neurological deficits; Blood– brain barrier damage
Effective Strategies for the Treatment of Alzheimer’s Disease
edited by Hyuck Jin Lee, and Ben A. Bahr
submission deadline 15 Jun 2022 | Viewed by 116
Keywords: alzheimer's disease  ; amyloid proteins  ; amyloid-beta  ; tau  ; acetylcholinesterase (AChE)   ; metal ions  ; reactive; oxygen species (ROS); neurodegeneration
Alterations in D-amino Acid Metabolism in Psychiatric and Neurological Disorders submission deadline 15 Jun 2022 | Viewed by 240
Keywords: neurological disorders; psychiatric disorders; NMDA receptors; D-aspartate; D-serine
(This special issue belongs to the Section Molecular Medicine)
Novel Insights into the Physiological and Pathological Role of Leptin and Leptin Receptor submission deadline 15 Jun 2022 | 3 articles | Viewed by 2207
Keywords: leptin; leptin receptor; metabolic disorders; obesity; cancer
(This special issue belongs to the Section Cellular Biochemistry)
Advances in Immunogenetic Markers of Human Multifactorial Diseases
edited by
submission deadline 15 Jun 2022 | Viewed by 94
Keywords: immunogenetic and genetic predictive markers in multifactorial diseases; immunogenetics of aging-associated diseases; immunogenetic markers of neoplastic diseases; immunogenetic markers of cardiovascular diseases; immunogenetic markers of metabolic diseases; immunogenetic markers of organ-specific diseases; genetic predictive markers in immune diseases; immunogenetics of infectious diseases
(This special issue belongs to the Section Molecular Genetics)
The Many Faces of Autophagy: Balancing Survival and Cell Death
edited by
submission deadline 15 Jun 2022 | 1 articles | Viewed by 597
Keywords: autophagy; apoptosis; survival and cell death; mitophagy; vesicular trafficking; cancer therapy; exocytosis; exosomes; viral infection
(This special issue belongs to the Section Cellular Biochemistry)
Gastrointestinal Hormones submission deadline 20 Jun 2022 | 1 articles | Viewed by 857
Keywords: gastrointestinal hormones; enteroendocrine cells; appetite control; obesity; gut microbiota; metabolic diseases; intestinal disorders
Aging and Aging-Related Diseases in China
edited by
submission deadline 20 Jun 2022 | 1 articles | Viewed by 1631
Keywords: Aging;aging-related disease;antiaging therapy;senescence;damaged biomolecules;homeostasis
(This special issue belongs to the Section Molecular Medicine)
Women in Vascular Disease: from Pathology to Regenerative Engineering submission deadline 20 Jun 2022 | Viewed by 252
(This special issue belongs to the Section Molecular Medicine)
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