Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gap Junctions and Connexins in Health and Disease, 2nd Edition submission deadline 20 Sep 2024 | 1 articles | Viewed by 2448 | Submission Open
Keywords: connexin; connexon; hemichannel; gap junction; electrical synapse; communication; bystander effect
(This special issue belongs to the Section Molecular Medicine)
Extracellular Vesicles as Biomarkers and Pathologic or Therapeutic Agents in Motor Neuron Diseases submission deadline 20 Sep 2024 | Viewed by 361 | Submission Open
(This special issue belongs to the Section Biological Factors)
The Role of Tau Protein in Neurodegenerative Diseases
edited by and Valeria Melis
submission deadline 20 Sep 2024 | Viewed by 329 | Submission Open
Keywords: tau biology; toxicity; utility as a biomarker and for diagnoses; cellular and molecular mechanisms of neuropathology; mechanisms of the aggregation and formation of filaments and tangles; all aspects of tau genetics; tau and the immune system; tau as a therapeutic target: current status and progress
(This special issue belongs to the Section Biomacromolecules: Proteins)
Novel Insights into the Role of Autoantibodies in Diseases—2nd Edition
edited by
submission deadline 20 Sep 2024 | Viewed by 123 | Submission Open
Keywords: B cells; autoantibodies; peripheral blood; biomarkers; autoimmune diseases
(This special issue belongs to the Section Molecular Biomarkers)
Artificial Intelligence (AI) in Biomedicine submission deadline 30 Sep 2024 | 10 articles | Viewed by 20841 | Submission Open
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Neurological Disorders: From Molecular Mechanisms to Therapy Strategies submission deadline 30 Sep 2024 | 5 articles | Viewed by 20510 | Submission Open
Keywords: neurodegeneration; neuroprotection; novel therapies; natural molecules
(This special issue belongs to the Section Molecular Biology)
Effects of Weightlessness on Molecular Changes in Cellular Organisms, Animals and Plants
edited by
submission deadline 30 Sep 2024 | 8 articles | Viewed by 16470 | Submission Open
Keywords: cells; humans; animals; plants; microorganisms; microgravity; weightlessness; cancer research; tissue engineering; space-related health problems
(This special issue belongs to the Section Cellular Biochemistry)
Nutrition, Metabolism, and Obesity: Novel Strategies and Molecular Mechanisms—Future Perspectives submission deadline 30 Sep 2024 | 7 articles | Viewed by 13651 | Submission Open
Keywords: diet; nutrients; obesity; inflammation; fat; glucose intolerance; insulin resistance; fatty liver disease; metabolic syndrome
(This special issue belongs to the Section Molecular Medicine)
Novel Molecules for Cancer Treatment (2nd Edition) submission deadline 30 Sep 2024 | 6 articles | Viewed by 13475 | Submission Open
Keywords: cancer; small molecules; antibody– drug-conjugated; tyrosine kinase inhibitors; target therapy; monoclonal antibodies; immunotherapy; natural compounds
(This special issue belongs to the Section Molecular Medicine)
Mitochondrial Quality Control in Aging and Neurodegeneration
edited by Sofie Lautrup
submission deadline 30 Sep 2024 | 5 articles | Viewed by 13142 | Submission Open
Keywords: mitochondria; quality control; mitochondrial biogenesis; mitochondrial dynamics; fission; fusion; mitophagy; mitochondrial degradation; cellular metabolism; aging; neurodegeneration; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease
(This special issue belongs to the Section Cellular Biochemistry)
Functional Peptides and Their Interactions submission deadline 30 Sep 2024 | 5 articles | Viewed by 8964 | Submission Open
Keywords: naturally occurring peptides; peptide engineering; peptide interactions; peptide self-assembly; peptide structure; small proteins; molecular therapeutics; biomaterials; biocatalysts
(This special issue belongs to the Section Molecular Structure and Dynamics)
Advances in β3-Adrenoceptor submission deadline 30 Sep 2024 | 4 articles | Viewed by 8225 | Submission Open
Keywords: β 3-adrenoceptor; cardiovascular diseases; cancer; prematurity; hypoxia/hyperoxia; neurodegenerative diseases; retinopathy
Novel Insights into Autoimmune/Autoinflammatory Skin Diseases submission deadline 30 Sep 2024 | 5 articles | Viewed by 6732 | Submission Open
Keywords: autoimmune/autoinflammatory skin diseases; omics; bioinformatics; pathogenesis; tailored medicine
(This special issue belongs to the Section Molecular Medicine)
Cellular and Molecular Mechanisms of Endometriosis
edited by , Alessandra Andrisani and Chiara Sabbadin
submission deadline 30 Sep 2024 | 4 articles | Viewed by 6731 | Submission Open
Keywords: endocrine dysfunction in endometriosis; glycosylphosphatidylinositols (GPIs) and GPI-anchored proteins; oxidative stress markers (glutathione; carbonic anhydrase; etc.); endometriosis and deep endometriosis; endometriosis-related immune system
(This special issue belongs to the Section Molecular Biology)
Interface of Aging and Biomaterials: 2nd Edition
edited by
submission deadline 30 Sep 2024 | 3 articles | Viewed by 6341 | Submission Open
Keywords: aging; senescence; geroscience; biomolecules; biomaterials; biocompatibility; nanoparticles; hydrogels
(This special issue belongs to the Section Biological and Bio- Materials)
Biomarkers of Cardiovascular and Cerebrovascular Diseases submission deadline 30 Sep 2024 | 5 articles | Viewed by 4430 | Submission Open
Keywords: biomarkers; cardiovascular disease; cerebrovascular disease; cardiovascular therapy; diagnosis
(This special issue belongs to the Section Molecular Biomarkers)
Molecular Advances in Mechanism and Regulation of Lifespan and Aging
edited by Mark McCormick
submission deadline 30 Sep 2024 | 2 articles | Viewed by 4360 | Submission Open
Keywords: aging; lifespan; healthspan
(This special issue belongs to the Section Molecular Biology)
New Insights into Mechanisms and Therapeutics for Cardiovascular Disorders
edited by , and Tarun W. Dasari
submission deadline 30 Sep 2024 | 2 articles | Viewed by 2937 | Submission Open
Keywords: brain heart-axis; heart & stroke; stress-induced cardiomyopathy; cardiovascular disease
(This special issue belongs to the Section Molecular Medicine)
Molecular Profiling and Identification of Molecular Signatures Associated with Natural Products
edited by
submission deadline 30 Sep 2024 | 2 articles | Viewed by 2645 | Submission Open
Keywords: natural product; molecular mechanisms; repurposed molecules; disease model; human health
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Programmed Cell Death (Apoptosis): Molecular Mechanisms and Implications for New Drug Discovery submission deadline 30 Sep 2024 | 1 articles | Viewed by 2471 | Submission Open
Keywords: programmed cell death; apoptosis; molecular aspects of apoptosis; apoptosis regulation; drug discovery; emerging therapeutic approaches
(This special issue belongs to the Section Cellular Biochemistry)
The Role of Cholinesterases in Alzheimer’s Disease and Other Neurodegenerative Disorders
edited by
submission deadline 30 Sep 2024 | 2 articles | Viewed by 2231 | Submission Open
Keywords: Alzheimer’ s disease; acetylcholinesterase; butyrylcholinesterase; enzymatic properties; non-enzymatic properties; neuroinflammation; drug development; neuroimaging
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Aptamer Therapeutics in Cancers: New Advances and Future Trends submission deadline 30 Sep 2024 | 1 articles | Viewed by 1949 | Submission Open
Keywords: aptamers; cancer; targeted therapy; aptamer-based conjugates; aptamer-conjugated nanoparticles
(This special issue belongs to the Section Molecular Medicine)
Targeting Neuroinflammation and Insulin Resistance for a Healthy Brain: Prevention and Treatment of Neurological and Psychiatric Disorders submission deadline 30 Sep 2024 | 1 articles | Viewed by 1523 | Submission Open
Keywords: insulin receptor substrates; microglia; degenerative diseases; psychiatric disorders; nutrition
(This special issue belongs to the Section Molecular Medicine)
Recent Trends in Kidney and Cardiovascular Diseases
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1506 | Submission Open
Keywords: chronic kidney disease; cardiovascular risk; albuminuria; epidemiology; estimated glomerular filtration rate
(This special issue belongs to the Section Molecular Medicine)
The Role of Modulating Intracellular Signaling in Immune System
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 1001 | Submission Open
Keywords: signaling pathway; inflammation; autoimmune disease; treatment
(This special issue belongs to the Section Molecular Biology)
New Insights into the Membranes of Anoxygenic Phototrophic Bacteria submission deadline 30 Sep 2024 | 1 articles | Viewed by 868 | Submission Open
Keywords: anoxygenic phototrophs; light harvesting; membrane dynamics; molecular evolution; reaction centers
(This special issue belongs to the Section Molecular Structure and Dynamics)
Genetic and Structural Analyses of SARS-CoV-2 and Its Variants
edited by
submission deadline 30 Sep 2024 | 1 articles | Viewed by 683 | Submission Open
Keywords: SARS-CoV-2 variants; protein variants; protein structure; virus evolution; mutations; structural bioinformatics; molecular phylogenesis; host– pathogen molecular interactions; molecular immunology; drug discovery
(This special issue belongs to the Section Molecular Structure and Dynamics)
Cutting-Edge Research on the Analysis of Small Biomolecules in Foods, Plants, and Biological Samples, Volume II submission deadline 30 Sep 2024 | 1 articles | Viewed by 635 | Submission Open
Keywords: bioactive food ingredients (primary and secondary metabolites); secondary metabolites— natural products liquid chromatography-mass spectrometry; Fourier transform infrared (FTIR) and Raman spectroscopic analysis; gas chromatography-mass spectrometry; high-resolution mass spectrometry; lipids— amino acids— carbohydrates; polyphenols– terpenes
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Rare Diseases: From Molecular Pathways to Therapeutic Strategies 2.0
edited by
submission deadline 30 Sep 2024 | Viewed by 614 | Submission Open
Keywords: adeno-associated virus  ; gene editing  ; metabolic diseases  ; lysosomal disorders  ; CRISPR  ; inborn errors of metabolism  ; neuromuscular disease
(This special issue belongs to the Section Molecular Medicine)
Insights into the Oral Microbiome and Its Modulation submission deadline 30 Sep 2024 | Viewed by 513 | Submission Open
Keywords: oral microbiome; oral infectious diseases; systemic disease
(This special issue belongs to the Section Molecular Biology)
Glial Cross-Talk in Central Nervous System Health and Disease submission deadline 30 Sep 2024 | Viewed by 451 | Submission Open
Keywords: glial physiology; glial cross-talk in CNS homeostasis; glial cross-talk in neuroinflammation; glial cross-talk in CNS diseases
(This special issue belongs to the Section Molecular Biology)
Epigenetics in Parathyroid Tumors submission deadline 30 Sep 2024 | Viewed by 333 | Submission Open
Keywords: parathyroid disorders; parathyroid adenomas; parathyroid cancers; epigenetics; LncRNAs; microRNAs; circular RNAs; DNA methylation; DNA acetylation
(This special issue belongs to the Section Molecular Medicine)
Plant-Microbe-Insect Interactions
edited by and Xueke Gao
submission deadline 30 Sep 2024 | Viewed by 258 | Submission Open
Keywords: plant– microbe– insect interactions; plant defense; insects; pest control; microbiology
(This special issue belongs to the Section Cellular Biochemistry)
Gene Mutations in Retinal Dystrophies
edited by Benedetto Falsini and
submission deadline 30 Sep 2024 | Viewed by 257 | Submission Open
Keywords: genes; retina; inherited retinal dystrophies; phenotype
Redox Balance and Proteostasis Surveillance in Neurodegenerative Disorders submission deadline 30 Sep 2024 | Viewed by 230 | Submission Open
Keywords: redox homeostasis; oxidative stress; antioxidant response; proteostasis; protein folding; protein oxidation; unfolded protein response; ubiquitin proteosome system; autophagy; neurodegeneration
(This special issue belongs to the Section Molecular Medicine)
Advanced Organometallic Syntheses for Biomedical Applications
edited by Bala Krishna Moku
submission deadline 30 Sep 2024 | Viewed by 219 | Submission Open
Keywords: advanced organometallic syntheses; biomedical applications; drug discovery; disease treatment; imaging; targeted therapy
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Biomolecules in Forensic Molecular Genetics
edited by
submission deadline 30 Sep 2024 | Viewed by 183 | Submission Open
Keywords: forensic; DNA; RNA; protein; mtDNA; epigenetics; microbiome
(This special issue belongs to the Section Molecular Genetics)
Recent Advances in the Structural and Functional Properties of Glutamate Dehydrogenase
edited by
submission deadline 30 Sep 2024 | Viewed by 181 | Submission Open
Keywords: glutamate dehydrogenase; GLUD1; GLUD2; structure-function relationships; neurodegenerative disorders
(This special issue belongs to the Section Enzymology)
New Insights and Potential Therapeutic Options in Leukemia Metabolism Research
edited by
submission deadline 30 Sep 2024 | Viewed by 170 | Submission Open
Keywords: acute myeloid leukemia (AML); chronic myeloid leukemia (CML); acute lymphocytic leukemia (ALL); chronic lymphocytic leukemia (CLL); tumor metabolism; metabolic rewiring
(This special issue belongs to the Section Molecular Medicine)
New Insights into Kidney Disease Development and Therapy Strategies submission deadline 1 Oct 2024 | 3 articles | Viewed by 3434 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Molecular Advances in Rett Syndrome and Other Chromatin Related Disorders
edited by and Salvatore Fioriniello
submission deadline 1 Oct 2024 | Viewed by 236 | Submission Open
Keywords: Rett syndrome and other chromatin disorders; epigenetic diseases; molecular alterations in Rett syndrome and other chromatin diseases; novel genes associated with chromatin disorders; MeCP2-mediated molecular mechanisms; roles of epigenetic modulators in chromatin-related diseases; preclinical studies for chromatin diseases; novel diagnostic; prognostic and therapeutic approaches for chromatin disorders
(This special issue belongs to the Section Molecular Medicine)
Molecular Pathology, Diagnostics and Therapeutics of Retinal Diseases
edited by
submission deadline 15 Oct 2024 | 6 articles | Viewed by 17697 | Submission Open
Keywords: retina; macula; macular edema; inflammatory mediators; optical coherence tomography; retinal imaging; biochemical marker; biomarker; pharmacological targeting
(This special issue belongs to the Section Molecular Medicine)
Muscular Dystrophy: From Molecular Basis to Therapies submission deadline 15 Oct 2024 | 5 articles | Viewed by 16709 | Submission Open
Keywords: muscular dystrophies; muscle regeneration; extracellular matrix; satellite cells; therapeutic approaches; animal models; clinical trials
(This special issue belongs to the Section Molecular Biology)
Mechanisms and Kinetics of Interactions of Biomolecules at Interfaces: 2nd Edition submission deadline 15 Oct 2024 | 4 articles | Viewed by 7898 | Submission Open
Keywords: biomolecule adsorption; kinetics of biomolecule adsorption; mechanisms of biomolecule deposition; interactions of biomolecules; techniques for the detection of biomolecules at solid substrates; interactions of proteins with biomolecules/biopolymers; protein and biomolecule systems; protein and biomolecule complexes
(This special issue belongs to the Section Biological and Bio- Materials)
Antibiotic Resistance Mechanisms and Their Potential Solutions
edited by Sung-Pin Tseng, and
submission deadline 15 Oct 2024 | 3 articles | Viewed by 5573 | Submission Open
Keywords: antibiotic resistance; antimicrobial development; molecular mechanism; priority for antibiotics; newly therapeutic approach
(This special issue belongs to the Section Molecular Biology)
TRP Channels in Cardiovascular and Inflammatory Disease
edited by and Soraia Katia Pereira Costa
submission deadline 15 Oct 2024 | 3 articles | Viewed by 4792 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
New Insights into Cardiovascular Immunology
edited by Susanne Sattler, Pilar Martín and Stephen Malin
submission deadline 15 Oct 2024 | 1 articles | Viewed by 2547 | Submission Open
Keywords: inflammation; autoimmunity; atherosclerosis; myocarditis; heart failure
(This special issue belongs to the Section Molecular Medicine)
Role of Neuroactive Steroids in Health and Disease: 2nd Edition submission deadline 15 Oct 2024 | 3 articles | Viewed by 1654 | Submission Open
Keywords: neurosteroids; neurodegenerative disorders; psychiatric disorders; physiological effects
(This special issue belongs to the Section Molecular Biology)
Advances in Nano-Based Drug Delivery: Unveiling the Next Frontier submission deadline 15 Oct 2024 | 1 articles | Viewed by 1611 | Submission Open
Keywords: targeted drug delivery; smart nanoformulation; controlled drug release; biocompatible nanocarriers; extracellular vesicles; immunotherapy
(This special issue belongs to the Section Biological and Bio- Materials)
Molecular and Cell Biology in Endometriosis and Endometrial Cancer: 2nd Edition submission deadline 15 Oct 2024 | 1 articles | Viewed by 846 | Submission Open
Keywords: endometriosis; endometrial cancer; ovarian cancer; molecular basis of endometriosis and endometrial cancer; single cell transcriptomics; spatial transcriptomics; multiomics; genomics; proteomics; epigenomics; metabolomics
(This special issue belongs to the Section Molecular Biology)
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