Synthetic Chemistry in Drug Discovery: Novel Compounds for Antimicrobial and Antioxidant Applications
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 16 October 2025 | Viewed by 54
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue focuses on recent advances in synthetic chemistry targeting the discovery of novel antimicrobial, antiproliferative, and antioxidant agents. The emergence of drug-resistant pathogens and oxidative stress-related disorders highlights the urgent need for innovative therapeutic strategies. Synthetic approaches enable the rational design and structural optimization of small molecules with improved efficacy, selectivity, and pharmacokinetic profiles. This Special Issue invites original research and review articles on the synthesis, characterization, and biological evaluation of active compounds with antimicrobial, antiproliferative, and antioxidant properties. Contributions exploring structure–activity relationships, natural product-inspired scaffolds, hybrid molecules, and mechanisms of action are encouraged. Studies employing in vitro, in vivo, or in silico methods to validate bioactivity are welcome. The goal is to provide a multidisciplinary platform integrating synthetic methodologies with pharmacological insights to accelerate the development of effective therapeutic candidates.
Dr. Hawraz Ibrahim M. Amin
Guest Editor
Manuscript Submission Information
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Keywords
- synthetic chemistry
- drug discovery
- essential oils
- antimicrobial activity
- antiproliferative agents
- antioxidant properties
- bioactive molecules
- structure–activity relationship
- natural product derivatives
- medicinal chemistry
- chemical synthesis
- pharmacological evaluation
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