Metabolic Syndrome and Type 2 Diabetes: From Molecular Pathogenesis to Novel Therapies
A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 59
Special Issue Editor
Interests: chronic kidney disease; fatty liver disease; herbal pharmacology; insulin resistance; lipid disorders; metabolic syndrome; obesity; pharmacokinetics and drug interactions; type 2 diabetes and its complications
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolic syndrome and type 2 diabetes are closely intertwined conditions that pose significant global health challenges. Metabolic syndrome is characterized by a cluster of factors including obesity, dyslipidaemia, hypertension, and insulin resistance, which collectively increase the risk of developing type 2 diabetes and cardiovascular diseases. The molecular pathogenesis of type 2 diabetes involves complex interplays between genetic predisposition, lifestyle factors, and metabolic dysregulation, leading to impaired insulin secretion and action. Recent advancements in omics technologies and molecular biology have shed light on the underlying mechanisms, such as gut dysbiosis, chronic inflammation, mitochondrial dysfunction, and altered adipokine signalling. However, effective therapies that address the multifaceted nature of these conditions remain limited.
This Special Issue aims to gather cutting-edge research and comprehensive reviews that elucidate the molecular pathogenesis of metabolic syndrome and type 2 diabetes, as well as explore its complications and novel therapeutic strategies. We welcome submissions focusing on basic research, translational studies, and clinical trials that contribute to a deeper understanding of these conditions and offer innovative solutions for their management.
Dr. Srinivas Nammi
Guest Editor
Manuscript Submission Information
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Keywords
- metabolic syndrome
- type 2 diabetes
- insulin resistance
- molecular pathogenesis
- novel therapies
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