Biomolecules | Highly Cited Papers in 2024–2025 in the “Molecular Biophysics: Structure, Dynamics, and Function” Section

All of the articles published in our journal are open access, granting our readers free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below:

1. “Phenotypic Heterogeneity, Bidirectionality, Universal Cues, Plasticity, Mechanics, and the Tumor Microenvironment Drive Cancer Metastasis”
by Claudia Tanja Mierke
Biomolecules 2024, 14(2), 184; https://doi.org/10.3390/biom14020184
Full text available online: https://www.mdpi.com/2218-273X/14/2/184

2. “Epigenetic Properties of Compounds Contained in Functional Foods Against Cancer”
by Giulia Casari, Brenda Romaldi, Andrea Scirè, Cristina Minnelli, Daniela Marzioni, Gianna Ferretti and Tatiana Armeni
Biomolecules 2025, 15(1), 15; https://doi.org/10.3390/biom15010015
Full text available online: https://www.mdpi.com/2218-273X/15/1/15

3. “Integrating Computational Design and Experimental Approaches for Next-Generation Biologics”
by Ahrum Son, Jongham Park, Woojin Kim, Wonseok Lee, Yoonki Yoon, Jaeho Ji and Hyunsoo Kim
Biomolecules 2024, 14(9), 1073; https://doi.org/10.3390/biom14091073
Full text available online: https://www.mdpi.com/2218-273X/14/9/1073

4. “Recent Advances in Metalloproteomics”
by James P. C. Coverdale, Sirilata Polepalli, Marco A. Z. Arruda, Ana B. Santos da Silva, Alan J. Stewart and Claudia A. Blindauer
Biomolecules 2024, 14(1), 104; https://doi.org/10.3390/biom14010104
Full text available online: https://www.mdpi.com/2218-273X/14/1/104

5. “Structure and Dynamics of the Bacterial Flagellar Motor Complex”
by Shuichi Nakamura and Tohru Minamino
Biomolecules 2024, 14(12), 1488; https://doi.org/10.3390/biom14121488
Full text available online: https://www.mdpi.com/2218-273X/14/12/1488

6. “Bacterial Decontamination of Water-Containing Objects Using Piezoelectric Direct Discharge Plasma and Plasma Jet”
by Evgeny M. Konchekov, Victoria V. Gudkova, Dmitriy E. Burmistrov, Aleksandra S. Konkova, Maria A. Zimina, Mariam D. Khatueva, Vlada A. Polyakova, Alexandra A. Stepanenko, Tatyana I. Pavlik, Valentin D. Borzosekov et al.
Biomolecules 2024, 14(2), 181; https://doi.org/10.3390/biom14020181
Full text available online: https://www.mdpi.com/2218-273X/14/2/181

7. “Ion Signaling in Cell Motility and Development in Dictyostelium discoideum”
by Yusuke V. Morimoto
Biomolecules 2024, 14(7), 830; https://doi.org/10.3390/biom14070830
Full text available online: https://www.mdpi.com/2218-273X/14/7/830

8. “Computational Methods to Predict Conformational B-Cell Epitopes”
by M. Carroll, E. Rosenbaum and R. Viswanathan
Biomolecules 2024, 14(8), 983; https://doi.org/10.3390/biom14080983
Full text available online: https://www.mdpi.com/2218-273X/14/8/983

9. “Chaga Mushroom Triterpenoids Inhibit Dihydrofolate Reductase and Act Synergistically with Conventional Therapies in Breast Cancer”
by Junbiao Wang, Daniela Beghelli, Augusto Amici, Stefania Sut, Stefano Dall’Acqua, Giulio Lupidi, Diego Dal Ben, Onelia Bistoni, Daniele Tomassoni, Barbara Belletti et al.
Biomolecules 2024, 14(11), 1454; https://doi.org/10.3390/biom14111454
Full text available online: https://www.mdpi.com/2218-273X/14/11/1454

10. “Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects”
by Mohamad Bakkar, Sara Khalil, Komal Bhayekar, Narva Deshwar Kushwaha, Amirreza Samarbakhsh, Sadaf Dorandish, Holly Edwards, Q. Ping Dou, Yubin Ge and Navnath S. Gavande
Biomolecules 2025, 15(2), 240; https://doi.org/10.3390/biom15020240
Full text available online: https://www.mdpi.com/2218-273X/15/2/240