Biomolecules | Highly Cited Papers in 2024–2025 in the “Molecular Reproduction” Section

All of the articles published in our journal are open access, granting our readers free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below:

1. “Current Status and Future Prospects of Stem Cell Therapy for Infertile Patients with Premature Ovarian Insufficiency”
by Hye Kyeong Kim and Tae Jin Kim
Biomolecules 2024, 14(2), 242; https://doi.org/10.3390/biom14020242
Full text available online: https://www.mdpi.com/2218-273X/14/2/242

2. “Adenomyosis and Abnormal Uterine Bleeding: Review of the Evidence”
by Marwan Habiba, Sun-Wei Guo and Giuseppe Benagiano
Biomolecules 2024, 14(6), 616; https://doi.org/10.3390/biom14060616
Full text available online: https://www.mdpi.com/2218-273X/14/6/616

3. “Potential Causal Association between Plasma Metabolites, Immunophenotypes, and Female Reproductive Disorders: A Two-Sample Mendelian Randomization Analysis”
by Hui-Hui Shen, Yang-Yang Zhang, Xuan-Yu Wang, Cheng-Jie Wang, Ying Wang, Jiang-Feng Ye and Ming-Qing Li
Biomolecules 2024, 14(1), 116; https://doi.org/10.3390/biom14010116
Full text available online: https://www.mdpi.com/2218-273X/14/1/116

4. “Endometrial Receptivity–Lessons from “Omics”
by Louie Ye and Evdokia Dimitriadis
Biomolecules 2025, 15(1), 106; https://doi.org/10.3390/biom15010106
Full text available online: https://www.mdpi.com/2218-273X/15/1/106

5. “Mechanisms of Hormonal, Genetic, and Temperature Regulation of Germ Cell Proliferation, Differentiation, and Death During Spermatogenesis”
by María Maroto, Sara N. Torvisco, Cristina García-Merino, Raúl Fernández-González and Eva Pericuesta
Biomolecules 2025, 15(4), 500; https://doi.org/10.3390/biom15040500
Full text available online: https://www.mdpi.com/2218-273X/15/4/500

6. “Investigation of Uterine Fluid Extracellular Vesicles’ Proteomic Profiles Provides Novel Diagnostic Biomarkers of Bovine Endometritis”
by Johanna Piibor, Andres Waldmann, Madhusha Prasadani, Ants Kavak, Aneta Andronowska, Claudia Klein, Suranga Kodithuwakku and Alireza Fazeli
Biomolecules 2024, 14(6), 626; https://doi.org/10.3390/biom14060626
Full text available online: https://www.mdpi.com/2218-273X/14/6/626

7. “Protective Role of Physical Activity and Antioxidant Systems During Spermatogenesis”
by Cristina Antinozzi, Luigi Di Luigi, Laura Sireno, Daniela Caporossi, Ivan Dimauro and Paolo Sgrò
Biomolecules 2025, 15(4), 478; https://doi.org/10.3390/biom15040478
Full text available online: https://www.mdpi.com/2218-273X/15/4/478

8. “Molecular Mechanism of Oocyte Activation in Mammals: Past, Present, and Future Directions”
by Hibiki Sugita, Shunsuke Takarabe, Atsuko Kageyama, Yui Kawata and Junya Ito
Biomolecules 2024, 14(3), 359; https://doi.org/10.3390/biom14030359
Full text available online: https://www.mdpi.com/2218-273X/14/3/359

9. “Single-Nucleus RNA-Seq Reveals Spermatogonial Stem Cell Developmental Pattern in Shaziling Pigs”
by Xiangwei Tang, Chujie Chen, Saina Yan, Anqi Yang, Yanhong Deng, Bin Chen and Jingjing Gu
Biomolecules 2024, 14(6), 607; https://doi.org/10.3390/biom14060607
Full text available online: https://www.mdpi.com/2218-273X/14/6/607

10. “Aflatoxin Exposure-Caused Male Reproductive Toxicity: Molecular Mechanisms, Detoxification, and Future Directions”
by Dongyun Ye, Zhihui Hao, Shusheng Tang, Tony Velkov and Chongshan Dai
Biomolecules 2024, 14(11), 1460; https://doi.org/10.3390/biom14111460
Full text available online: https://www.mdpi.com/2218-273X/14/11/1460