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Biomolecules
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28 July 2026
Biomolecules | Highly Cited Papers in 2025–2026 in the “Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates” Section


All of the articles published in Biomolecules (ISSN 2218-273X) are open access, meaning you have free and unlimited access to the full text. We invite you to read the most highly cited papers published in 2025 and 2026 in the section “Biomacromolecules: Proteins, Nucleic Acids and Carbohydrates”, which are listed below:

1. “Lactobacilli-Derived Microbe-Associated Molecular Patterns (MAMPs) in Host Immune Modulation”
by Salvatore Furnari, Ruben Ciantia, Adriana Garozzo, Pio Maria Furneri and Virginia Fuochi
Biomolecules 2025, 15(11), 1609; https://doi.org/10.3390/biom15111609
Full text available online: https://www.mdpi.com/2218-273X/15/11/1609

2. “Nav1.8 and Chronic Pain: From Laboratory Animals to Clinical Patients”
by Yu-Feng Xie
Biomolecules 2025, 15(5), 694; https://doi.org/10.3390/biom15050694
Full text available online: https://www.mdpi.com/2218-273X/15/5/694

3. “Hyaluronic Acid in Immune Response”
by Lech Chrostek and Bogdan Cylwik
Biomolecules 2025, 15(7), 1008; https://doi.org/10.3390/biom15071008
Full text available online: https://www.mdpi.com/2218-273X/15/7/1008

4. “The Versatility of Serine Proteases from Brazilian Bothrops Venom: Their Roles in Snakebites and Drug Discovery”
by Marcela Romanazzi, Eloise T. M. Filardi, Geovanna M. M. Pires, Marcos F. Cerveja, Guilherme Melo-dos-Santos, Isadora S. Oliveira, Isabela G. Ferreira, Felipe A. Cerni, Norival Alves Santos-Filho, Wuelton M. Monteiro et al.
Biomolecules 2025, 15(2), 154; https://doi.org/10.3390/biom15020154
Full text available online: https://www.mdpi.com/2218-273X/15/2/154

5. “The Role of Substance P in Corneal Homeostasis”
by Irmina Jastrzębska-Miazga, Bartosz Machna, Dorota Wyględowska-Promieńska and Adrian Smędowski
Biomolecules 2025, 15(5), 729; https://doi.org/10.3390/biom15050729
Full text available online: https://www.mdpi.com/2218-273X/15/5/729

6. “Heavy Chalcogen Properties of Sulfur and Selenium Enhance Nucleic Acid-Based Therapeutics”
by Stephen J. Dansereau and Jia Sheng
Biomolecules 2025, 15(2), 218; https://doi.org/10.3390/biom15020218
Full text available online: https://www.mdpi.com/2218-273X/15/2/218

7. “Electrostatic Effects on Tau Nanocondensates”
by Phoebe S. Tsoi, Lathan Lucas, Derek Rhoades, Josephine C. Ferreon and Allan Chris M. Ferreon
Biomolecules 2025, 15(3), 406; https://doi.org/10.3390/biom15030406
Full text available online: https://www.mdpi.com/2218-273X/15/3/406

8. “Scanning Tunneling Microscope Measurement of Proteasome Conductance”
by Sepideh Afsari, Eathen Ryan, Brian Ashcroft, Xu Wang and Stuart Lindsay
Biomolecules 2025, 15(4), 496; https://doi.org/10.3390/biom15040496
Full text available online: https://www.mdpi.com/2218-273X/15/4/496

9. “Presenilin-1 Familial Alzheimer Mutations Impair γ-Secretase Cleavage of APP Through Stabilized Enzyme–Substrate Complex Formation”
by Sujan Devkota, Masato Maesako and Michael S. Wolfe
Biomolecules 2025, 15(7), 955; https://doi.org/10.3390/biom15070955
Full text available online: https://www.mdpi.com/2218-273X/15/7/955

10. “Insights into Membrane Damage by α-Helical and β-Sheet Peptides”
by Warin Rangubpit, Hannah E. Distaffen, Bradley L. Nilsson and Cristiano L. Dias
Biomolecules 2025, 15(7), 973; https://doi.org/10.3390/biom15070973
Full text available online: https://www.mdpi.com/2218-273X/15/7/973

11. “Class IIa HDACs Are Important Signal Transducers with Unclear Enzymatic Activities”
by Claudio Brancolini
Biomolecules 2025, 15(8), 1061; https://doi.org/10.3390/biom15081061
Full text available online: https://www.mdpi.com/2218-273X/15/8/1061

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