Cancer Signaling Pathways, Crosstalk and Therapeutics
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cancer Biology".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 38536
Special Issue Editors
Interests: cancer cells; tumor microenvironment; cancer biology; cell culture; tumor biology; tumor cell culture, anti-microbial, anti-inflammation, host-microbe interaction
Special Issues, Collections and Topics in MDPI journals
Interests: inflammation and cancer biology; immunology and bacterial pathogenesis; mitochondrial metabolism; post-translational modification; dietary agents; drug discovery; protein structure biology; life-style and environmental cancer; risk factors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cancer is a major problem of disease worldwide and, each year, many millions of people are diagnosed with cancer around the world, and more than half of them die. Cancer ranks second, next to cardiovascular diseases, for causing the greatest number of deaths. Therefore, it is important to study cancer in depth. Cell death is an essential biological process in maintaining homeostasis, as well as in removing dead cells. Both cell growth and cell death are important mechanisms for cancer proliferation, development and for chemoresistance. Both mechanisms are complex, however, apoptosis, autophagy, necrosis, or necroptosis signaling cascade plays a crucial role. Moreover, tumor microenvironment has a significant impact on cell proliferation, death, metabolism and chemotherapy. Therefore, it is vital to consider all of these factors for chemotherapy. This Special Issue focuses on “Cancer Signaling Pathways, Crosstalk and Therapeutics”. The main objectives are not restricted to apoptosis, necrosis, autophagy, ferroptosis or lysosomal signaling cascade but also target various pathways for tumor annihilation, cell death for intrinsic and extrinsic apoptosis, novel plants, chemical drugs, nanomedicine or strategies targeting cancer promoting proteins (BH3, SMAC mimetics, cFLIP, XIAP).
This Special Issue welcomes the submission of original research and review articles focusing on cancer signaling pathways and therapeutics; however, research on new technologies employed for studying cancer biomarker identification, tracing cancer pathways, that will help us to understand cancer biology in depth is also welcome. This Special Issue will enlighten readers about new discoveries, advances, and development in cancer therapeutics.
Dr. Imran Khan
Dr. Faisal Aziz
Guest Editors
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Keywords
- cancer biology
- anticancer study
- signaling pathway
- apoptosis
- autophagy
- necrosis
- necroptosis
- nanomedicine
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