Gene Therapies for Regenerative Medicine

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Cellular and Molecular Bioengineering".

Deadline for manuscript submissions: 31 March 2026

Special Issue Editors


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Guest Editor
Centre of Regulatory Excellence, Duke-NUS Medical School, National University of Singapore, Singapore 169857, Singapore
Interests: cell & gene therapy; regenerative medicine; good manufacturing practices; regulatory science; policy innovation; quality management systems

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Guest Editor
Critical Analytics for Manufacturing Personalized-Medicine (CAMP), Singapore-MIT Alliance for Research and Technology Centre (SMART), Singapore, Singapore
Interests: bioanalytics; biocharacterization; cell therapy manufacturing; adventitious agent metabolism and detection; translation and innovation
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Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute to an exciting Special Issue of Bioengineering (in the Cellular and Molecular Bioengineering section) titled "Gene Therapies for Regenerative Medicine."

The field of regenerative medicine is experiencing unprecedented transformation through advancements in cell and gene therapy technologies. This Special Issue provides a unique opportunity to showcase cutting-edge research that harnesses cellular and genetic engineering approaches to regenerative medicine applications.

We cordially invite submissions of original research articles, comprehensive reviews, and technological reports that explore the following areas:

  • Stem and progenitor cell engineering for regenerative applications;
  • Genetic engineering techniques including gene editing, silencing, and activation for enhanced tissue healing;
  • Innovative delivery systems encompassing both viral and non-viral vector technologies;
  • Tissue-specific differentiation, targeting strategies and integration with biomaterial scaffolds;
  • Translational advances from preclinical studies to clinical applications.

We are interested in research addressing critical challenges in the field, including delivery efficiency, cellular targeting specificity, safety profiles, engraftment and dosage optimization, therapy product consistency and long-term therapeutic efficacy. Studies focusing on applications in bone, cardiovascular, cartilage, eye, endocrine and metabolism, neural, reproductive system, skin, or organ regeneration are encouraged.

This Special Issue aims to create a multidisciplinary forum for researchers to further advance the translation of cell and gene therapies toward meaningful clinical impact in regenerative medicine.

We look forward to receiving your high-quality contributions and to facilitating scientific dialogue that will shape the future of this rapidly evolving field.

Yours Sincerely,

Dr. Eddie Han Pin Tan
Dr. Yie Hou Lee
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cell therapy
  • gene therapy
  • regenerative medicine
  • gene delivery
  • stem cell engineering
  • tissue engineering
  • biomaterials
  • cell reprogramming
  • viral vectors

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Published Papers

This special issue is now open for submission.
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