Electromechanical Effects in Biomedical Science: Mechanisms, Materials, and Medical Applications

Dear Colleagues,

Electromechanical effects have emerged as a crucial concept bridging materials science and biomedical research. While traditionally studied in engineered materials, recent discoveries have illuminated their significant role in biological behaviors particularly in bone remodeling and mechanotransduction, and their use in electroactive scaffolds for tissue engineering, medical equipment such as wearable and implantable sensors, cardiac and muscular pacing systems as well as ultrasound-mediated therapies. This interdisciplinary field is now expanding rapidly, offering transformative insights into regenerative medicine, bioelectronic interfaces, smart biomaterials, ultrasound technologies, and drug delivery systems. This special issue aims to explore the multifaceted roles of electromechanical effects in biology and medicine and bring together cutting-edge research and perspectives exploring the fundamental mechanisms, technological applications, and therapeutic potentials of electromechanical phenomena in biological contexts. We invite authors to submit original research articles and review articles that focus on (but are not limited to) the following topics:

• Mechanisms of electromechanical effects in biological tissues
• Flexoelectricity vs. piezoelectricity: comparative roles in mechanobiology
• Theoretical/computational models of biological tissues including electromechanical effects
• Multiscale modeling of biological systems with electromechanical properties
• Advanced multiphasic systems in biomechanics and mechanobiology
• Development of smart biomaterials for tissue engineering
• Piezoelectric/flexoelectric polymers and composites in biomedical devices
• Tissue regeneration via electromechanical cues
• Smart materials in wearable health monitors
• Implantable smart devices for neuromodulation
• The role of electromechanical components in soft robotics and haptics
• Smart drug delivery and diagnostics
• Measurement techniques for electromechanical properties in biological samples
• Potential of electrical stimulation-based therapies
• AI and Machine Learning integration in electromechanically-induced biomedical simulation

Dr. Melika Mohammadkhah
Dr. Dragan Zoran Marinkovic
Dr. Paula Pascoal-Faria
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.