Engineering Intervertebral Disc Models: From Basic Science to Clinical Practice
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".
Deadline for manuscript submissions: 10 September 2026 | Viewed by 3060
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cell isolation techniques, experimental in vitro cell models, and biomaterial science are becoming increasingly important to modern medicine. Disc degeneration is a key research focus, combined with the development of materials that are biocompatible with natural tissue and can serve as artificial, implantable disc replacements. Advances in in vitro cell models are crucial in disc applications, not only in the study of degenerative processes but also in the refinement of research and development in suitable biomaterials, tissue engineering in discs, and the in vitro evaluation of cell–material interactions and treatment options. We aim to cover some of the most important areas of preclinical and clinical medicine. These include basic science and preclinical research, such as cell isolation techniques, biomaterial development, in vitro cell modelling, the assessment of cell–material interactions and mechanisms of disc degeneration, clinical approaches, and treatment strategies. We hope that this Special Issue will enhance our understanding of the scientific basis of disc regeneration and provide knowledge on clinical management to assist clinicians and researchers in this field.
Dr. Lidija Gradišnik
Guest Editor
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Keywords
- intervertebral disc
- disc degeneration
- cell isolation
- cell cultures
- in vitro cell models
- 3D bioprinting
- treatment
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