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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Joint Biomechanics and Implant Design

edited by Ryan Willing and

Ryan Chapman

submission deadline 31 May 2026 | 13 articles | Viewed by 28469

Keywords: orthopedics; sports medicine; arthroplasty; prosthesis design; finite element analysis; joint motion simulators; imaging; contact mechanics; instability; loosening

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Measuring Outcomes and Impact Related to Assistive Technology and Accessibility for Disability

edited by Rochelle Mendonca, Qussai Obiedat and Roger O. Smith

submission deadline 31 May 2026 | 8 articles | Viewed by 17524

Keywords: assistive technology; disability; accessibility; measurement; outcomes; universal design

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Artificial Intelligence Revolution in Biomedical Image and Signal Processing: Innovations and Applications

edited by

Shih-Lun Chen

Liang-Hung Wang

and Tsung-Yi Chen

submission deadline 31 May 2026 | 8 articles | Viewed by 16630

Keywords: artificial intelligence techniques for biomedical signal and image processing; medical image processing; deep learning; AI-based diagnostic imaging; multimodal image fusion; early disease detection; image-guided surgery

(This special issue belongs to the Section Biosignal Processing)

Computer Vision and Machine Learning in Medical Applications, 2nd Edition

edited by

Chunhung Richard Lin

submission deadline 31 May 2026 | 9 articles | Viewed by 13654

Keywords: computer vision; machine learning; medical applications

(This special issue belongs to the Section Biosignal Processing)

Machine Learning, Artificial Intelligence and Medicine: The Interface of Medicine, Computer Science and Engineering

edited by Simon W. Rabkin

submission deadline 31 May 2026 | 6 articles | Viewed by 12543

Keywords: medical informatics; healthcare analytics; predictive modeling; digital health; precision medicine; machine learning; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Advancements in Biocompatible Materials for Implantable Medical Devices

edited by

Tarun Goswami

and

Farah Hamandi

submission deadline 31 May 2026 | 6 articles | Viewed by 11314

Keywords: biomaterials; clinical engineering; biomedical devices; cardiovascular engineering; biomedical instrumentation; biomechanical engineering; biomedical modeling; biomedical technology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Intelligent Health Management and Rehabilitation Technology: Integrating Large Language Models and AI Solutions

edited by Ning Deng

submission deadline 31 May 2026 | 6 articles | Viewed by 10278

Keywords: intelligent rehabilitation technology; health monitoring systems; machine learning in healthcare; intelligent nursing technology; proactive health management; large language models in healthcare; AI-assisted clinical decision-making; personalized rehabilitation strategies

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Biomedical Imaging, Biosignals and Healthcare

edited by

Ioannis Kakkos

George K. Matsopoulos

and

Athanasios Anastasiou

submission deadline 31 May 2026 | 4 articles | Viewed by 9803

Keywords: biomedical data processing; artificial intelligence in healthcare; medical image segmentation; predictive modeling in medicine; machine learning in diagnostics; personalized treatment planning; quantitative image analysis; AI-driven medical imaging; computational modeling in healthcare; real-time AI applications in medicine

(This special issue belongs to the Section Biosignal Processing)

Pathology–Therapeutics–Medicine of Vascular and Respiratory Diseases: Recent Progress Using CFD and AI

edited by

Hang Yi

and

Jianan Zhao

submission deadline 31 May 2026 | 4 articles | Viewed by 9739

Keywords: biofluids; biomechanics; drug delivery; medical device; pathophysiology; intervention; therapeutics; medicine; hemodynamics; neurovascular and cardiovascular diseases; respiratory airway diseases; computational fluid dynamics; multiphase/multispecies flow modeling; physiologically based pharmacokinetic/toxicokinetic models; machine learning and deep learning in healthcare

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Machine Learning and Deep Learning Applications in Healthcare, 2nd Edition

edited by

Jorge Mateo

and

Ana María Torres Aranda

submission deadline 31 May 2026 | 5 articles | Viewed by 6263

Keywords: machine learning; deep learning; big-data enabled healthcare systems; biomedical diagnostic techniques; diagnostic imaging; medical decision making; digital pathology; digital radiology; artificial neural networks; artificial intelligence; smart health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Diagnostic Imaging and Radiation Therapy in Biomedical Engineering

edited by

Carlo A. Mallio

submission deadline 31 May 2026 | 3 articles | Viewed by 5771

Keywords: diseases diagnostic; radiation therapy; biomedical engineering; imaging technology

(This special issue belongs to the Section Biosignal Processing)

Preclinical Evaluation of Biomaterials and Medical Devices for the Musculoskeletal System

edited by

Silvia Brogini

and Matilde Tschon

submission deadline 31 May 2026 | 1 articles | Viewed by 5338

Keywords: biomaterials and medical devices; preclinical testing; humanized advanced in vitro models; orthopaedic applications

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Three-Dimensional Culture Systems: Bridging Biology and Medicine

edited by

Fatima A. Merchant

submission deadline 31 May 2026 | 1 articles | Viewed by 4265

Keywords: 3D culture platforms; microengineered 3D systems; biomaterials for 3D culture; engineering complex 3D microenvironments; 3D systems for modeling disease and physiological processes; 3D culture-based therapies and diagnostic tools; translation of 3D systems for clinical applications

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Bioengineered Approaches to Oral-Systemic Disease Diagnostics and Therapeutics

edited by

João Miguel Marques dos Santos

submission deadline 31 May 2026 | 2 articles | Viewed by 4149

Keywords: bioengineering; oral health; systemic diseases; diagnostics; therapeutics; biomarkers

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Development of Biocatalytic Processes and Green Energy Technologies

edited by

Federico Zappaterra

Pier Paolo Giovannini

and

Lindomar Alberto Lerin

submission deadline 31 May 2026 | 2 articles | Viewed by 3663

Keywords: sustainable biocatalysis; enzymatic process and scale up; bio-based polymers; hybrid chemo-biotechnologies; green energy conversion

(This special issue belongs to the Section Biochemical Engineering)

Anaerobic Biotechnologies for Energy and Resource Recovery from Waste

edited by

Abid Hussain

and Kaushik Venkiteshwaran

submission deadline 31 May 2026 | 3 articles | Viewed by 3285

Keywords: anaerobic digestion; bioelectrochemical systems; solid-state fermentation; waste-to-energy conversion; resource recovery; biogas; SCFAs; microbial electrosynthesis; circular bioeconomy; organic waste valorization

(This special issue belongs to the Section Biochemical Engineering)

Engineering Human Performance: Advanced Monitoring and Intervention Technologies in Sports Science

edited by

Jorge Morais

submission deadline 31 May 2026 | 1 articles | Viewed by 2544

Keywords: sports technology; athlete development; wearable sensors; performance analysis; biomechanics; artificial intelligence; machine learning; data analytics; virtual reality; training optimization

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Applications of Transcranial Stimulation and EEG-Based Feedback Systems in Bioengineering

edited by Milan Pantovic and

Brach Poston

submission deadline 31 May 2026 | 1 articles | Viewed by 2507

Keywords: non-invasive brain stimulation; performance optimization; EEG-based feedback systems; wearable neuromodulation; virtual reality integration

(This special issue belongs to the Section Biosignal Processing)

New Sights of Data Analysis and Digital Model in Biomedicine

edited by

Robert Karpiński

submission deadline 31 May 2026 | 2 articles | Viewed by 2081

Keywords: artificial intelligence in medicine; machine learning for diagnosis; deep learning in medical imaging; predictive analytics in healthcare; AI-powered clinical decision support; natural language processing in biomedicine; data-driven disease diagnosis; digital twins in healthcare; big data in biomedical diagnostics; AI-enhanced biomarker discovery

(This special issue belongs to the Section Biosignal Processing)

Applied Biomechanics in Rehabilitation and Ergonomics

edited by Márcio Goethel

submission deadline 31 May 2026 | 2 articles | Viewed by 2040

Keywords: musculoskeletal; biomechanics; rehabilitation; ergonomics

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Artificial Intelligence in Bioengineering: Innovations, Challenges, and Future Directions

edited by

Daniele Giansanti

submission deadline 31 May 2026 | 1 articles | Viewed by 1426

Keywords: artificial intelligence; bioengineering; machine learning; biomedical imaging; precision medicine; digital twins; biomedical devices; explainable AI; drug discovery; multi-omics integration

(This special issue belongs to the Section Biosignal Processing)

Advancing Spinal Instability Diagnosis with Artificial Intelligence

edited by

John Hipp

submission deadline 31 May 2026 | 1 articles | Viewed by 1414

Keywords: spine; lumbar; cervical; thoracic; instability; stability; diagnosis; medical imaging; degenerative; trauma; intervertebral motion; spinal alignment; loss of motion segment integrity

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence and Machine Learning in Spine Research, 2nd Edition

edited by

Min Cheol Chang

submission deadline 31 May 2026 | 1 articles | Viewed by 1212

Keywords: pain; research; artificial intelligence; deep learning; machine learning

(This special issue belongs to the Section Biosignal Processing)

Advances in Wound Healing and Regenerative Medicine

edited by Sik Namgoong and

Shang-You Yang

submission deadline 31 May 2026 | 1 articles | Viewed by 1166

Keywords: wound healing; regenerative medicine; stem cells; tissue engineering; ECM; diabetic ulcers; microsurgical reconstruction; bioactive materials; cell-based therapy; translational models; DNA methylation; CRISPR technology; nanomedicine

(This special issue belongs to the Section Regenerative Engineering)

Bioengineering Intelligent Systems: From Robotic Manipulation to AI-Driven Healthcare Solutions

edited by

Tae-Seong Kim

submission deadline 31 May 2026 | 1 articles | Viewed by 1152

Keywords: intelligent robotics; medical AI; robotic manipulation; healthcare automation; machine learning in biomedicine; surgical robotics; Bio-inspired systems; AI-driven diagnostics.

(This special issue belongs to the Section Biosignal Processing)

Three-Dimensional Printing in Modern Dentistry: State of the Art, Benefits and Future Prospects

edited by

Saverio Capodiferro

Massimo Corsalini

and

Giuseppe D'Albis

submission deadline 31 May 2026 | 1 articles | Viewed by 911

Keywords: additive manufacturing; 3D printing; dentistry; CAD/CAM systems; biocompatible materials; clinical applications; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancing Theranostics Through Photodynamic Therapy

edited by Taokun Luo and Wenyao Zhen

submission deadline 31 May 2026 | Viewed by 592

Keywords: photodynamic therapy (PDT); theranostics; photosensitizers; light delivery systems; real-time imaging; targeted therapy; personalized medicine; translational research

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Therapeutic Solutions for Pain

edited by Farah Deba and

Olga Kopach

submission deadline 31 May 2026 | Viewed by 561

Keywords: tissue engineering; cell therapy; drug discovery; chronic pain; biomaterials; drug delivery; nanotechnology; pain signaling

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Generative AI for Biosignal and Medical Imaging Analysis

edited by Wei Peng, Tian Xia, Haoyu Chen and

Yante Li

submission deadline 31 May 2026 | Viewed by 457

Keywords: generative AI; AI for biomedicine; LLM in healthcare; digital health

(This special issue belongs to the Section Biosignal Processing)

Multimodal Neuroimaging Techniques: Progress and Application, Second Edition

edited by Frédéric Grouiller

submission deadline 31 May 2026 | Viewed by 375

Keywords: multimodal neuroimaging; MRI; MEG; EEG; fNIRS; PET; TMS; VR technology; imaging setups; brain function; multimodal signals processing; deep learning algorithms; artificial intelligence; brain computer interface

(This special issue belongs to the Section Biosignal Processing)

Advances in Catheter Ablation of Atrial Fibrillation

edited by

Alexandru Bejinariu

and Obaida Rana

submission deadline 31 May 2026 | Viewed by 332

Keywords: complex arrhythmias; pulmonary vein isolation; pulsed field ablation; electroanatomical mapping

(This special issue belongs to the Section Biosignal Processing)

Multiscale Computational Biomechanics and AI

edited by

Ramana Pidaparti

Jinxiang Xi

and

Israr Ibrahim

submission deadline 31 May 2026 | Viewed by 275

Keywords: multiscale biomechanics; computational modeling; machine learning in bioengineering; tissue mechanics; finite element analysis; AI in biomechanics; physics-informed neural networks (PINNs); markerless motion capture; generative AI; digital twin; biomechanical simulation; biofluid dynamics; mechanobiology; personalized medicine; biomedical applications

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Harnessing Microbes for Bioproduction: From Synthetic Biology to Bioprocess Scale-Up

edited by

Edmar Oliveira-Filho

Linda Guaman

Carlos Barba-Ostria

and Luiziana Ferreira Da Silva

submission deadline 31 May 2026 | Viewed by 246

Keywords: synthetic biology; metabolic engineering; enzyme engineering; bioproducts; biomanufacturing; bioprocess engineering; chemical engineering

(This special issue belongs to the Section Biochemical Engineering)

Advances in Additive Manufacturing Technologies in the Clinical, Pharmaceutical and Biomedical Sectors—Second Edition

edited by

Karthik K. Tappa

submission deadline 31 May 2026 | Viewed by 185

Keywords: 3D printing; bioprinting; bioactive materials; bioink; anatomical models; surgical guides; patient-specific implants; 3D-printed drug delivery systems; 3D-printed biomedical devices

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advanced Physical Techniques in Tissue Engineering and Regenerative Medicine

edited by

Alessandra Giuliani

Michele Furlani

and

Nicole Riberti

submission deadline 10 Jun 2026 | 7 articles | Viewed by 11198 | Submission Open

Keywords: tissue engineering; regenerative medicine; advanced imaging modalities; high-resolution microscopy; magnetic resonance imaging (MRI); computed tomography (CT); artificial intelligence (AI)

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics of Human Motion

edited by Meizi Wang and Xiaoling Hu

submission deadline 25 Jun 2026 | Viewed by 490 | Submission Open

Keywords: human movement analysis; gait analysis; sport performance; musculoskeletal biomechanics; injury prevention; wearable biomechanics sensors; motion capture techniques

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Resorption to Regeneration: Advanced Therapeutic Approaches in Contemporary Endodontics

edited by

Mohammad A. Sabeti

submission deadline 25 Jun 2026 | Viewed by 251 | Submission Open

Keywords: endodontic microsurgery; apico-marginal defects; regenerative endodontics; root resorption; surgical root repair; external resorption management; scaffold-based regenerative strategies

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics of Physical Exercise

edited by

Andrea Biscarini

submission deadline 30 Jun 2026 | 10 articles | Viewed by 22496 | Submission Open

Keywords: biomechanics; kinematics; kinetics; muscle activation; joint loads; proprioception; postural control and balance; neuromotor control; human movement; physical exercise; athletic training; athletic performance; sport; injury prevention; rehabilitation; exercise equipment; equipment design; ergonomics; motion analysis; force plates; electromyography; EMG; musculoskeletal modelling; simulation; sensors; imaging; magnetic resonance; MRI; artificial intelligence; robotics; new technologies

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Advancements in Biomechanical Gait Analysis: Implications for Footwear Biomechanics and Sports Injury Prevention

edited by

Yang Song

Dong Sun

and

Xuanzhen Cen

submission deadline 30 Jun 2026 | 4 articles | Viewed by 16595 | Submission Open

Keywords: human locomotion; motion capture technology; wearable sensors; biomechanical modeling; injury risk assessment; personalized footwear design; machine learning in biomechanics; sports science integration

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Anaerobic Digestion Advances in Biomass and Waste Treatment

edited by

Tina Kegl

and Breda Kegl

submission deadline 30 Jun 2026 | 12 articles | Viewed by 16077 | Submission Open

Keywords: waste management; biomass and waste pre-treatments; anaerobic digestion; modeling and optimization; biogas plants; biogas production; digestate treatment; microbial fuel cells; electricity production

(This special issue belongs to the Section Biochemical Engineering)

Advances in Medical 3D Vision: Voxels and Beyond

edited by Jiancheng Yang, Hongwei Li and Hieu Le

submission deadline 30 Jun 2026 | 3 articles | Viewed by 14155 | Submission Open

Keywords: medical 3D vision; artificial intelligence for health; 3D medical image analysis; voxel-based imaging; point clouds; mesh-based analysis; graph neural networks; implicit representations; deep geometric learning; interventional imaging; healthcare applications; digital twins

(This special issue belongs to the Section Biosignal Processing)

AI and Data Science in Bioengineering: Innovations and Applications

edited by

Muneer Ahmad

submission deadline 30 Jun 2026 | 9 articles | Viewed by 13797 | Submission Open

Keywords: AI; data science; bioengineering; biomedical engineering; predictive modeling; machine learning; smart biomaterials; tissue engineering

(This special issue belongs to the Section Biosignal Processing)

Biomedical Application of Big Data and Artificial Intelligence—Second Edition

edited by

Yan Pei

and

Jijiang Yang

submission deadline 30 Jun 2026 | 4 articles | Viewed by 11641 | Submission Open

Keywords: artificial intelligence; big data; image processing; data mining; soft computing; bioinformatics; bioengineering; healthcare

(This special issue belongs to the Section Biosignal Processing)

Label-Free Cancer Detection

edited by

Raphaël Canadas

submission deadline 30 Jun 2026 | 5 articles | Viewed by 11203 | Submission Open

Keywords: label-free; microfluidics; biomarkers; cancer; non-invasive; biosensors; nanotechnology

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

3D Cell Culture Systems: Current Technologies and Applications

edited by

Peggy Stock

submission deadline 30 Jun 2026 | 5 articles | Viewed by 10651 | Submission Open

Keywords: 3D cell culture; tissue engineering; biomaterials; drug discovery; cancer research; regenerative medicine; scaffold technology; high-throughput screening; organoids; in vitro models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Tissue Engineering and Regenerative Medicine Strategies for Biomedical Engineering

edited by Hun-Jin Jeong and

Solaiman Tarafder

submission deadline 30 Jun 2026 | 3 articles | Viewed by 10088 | Submission Open

Keywords: tissue engineering; regenerative medicine; bioprinting; microfluidics; tissues on chip

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Integrative Bioengineering in Orthopedic Surgery: From Regenerative Constructs to Precision Arthroplasty

edited by Man Soo Kim

submission deadline 30 Jun 2026 | 2 articles | Viewed by 9778 | Submission Open

Keywords: orthopedic bioengineering; tissue-engineered constructs; stem cell therapy; robotic surgery; AI-guided arthroplasty; smart implants; biomechanical modeling; scaffold-implant hybrid systems; regenerative surgery; precision orthopedics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Computational Imaging and Artificial Intelligence for Biomedical and Clinical Applications

edited by Nan Meng,

Jason Pui Yin Cheung

and Junming Shao

submission deadline 30 Jun 2026 | 7 articles | Viewed by 9746 | Submission Open

Keywords: computational imaging; artificial intelligence; deep learning; medical image analysis; medical diagnosis

(This special issue belongs to the Section Biosignal Processing)

Next-Generation Diagnostic and Therapy Systems for Neurodegenerative Diseases

edited by

Raji Sundararajan

and

Miad Faezipour

submission deadline 30 Jun 2026 | 3 articles | Viewed by 9067 | Submission Open

Keywords: Alzheimer's disease; Parkinson's disease; machine learning; deep learning; neurostimulation; neuromodulation; artificial intelligence models

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

New Sights of Deep Learning and Digital Model in Biomedicine

edited by

John A. St. Cyr

submission deadline 30 Jun 2026 | 5 articles | Viewed by 8706 | Submission Open

Keywords: deep learning; digital model; biomedicine

(This special issue belongs to the Section Biosignal Processing)

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