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  • Article
  • Open Access

Knockouts of Yeast Plasma Membrane Phosphate Transporters Alter Resistance to Heavy Metals

  • Larisa Ledova,
  • Lubov Ryazanova,
  • Ludmila Trilisenko,
  • Vladimir Ostroumov and
  • Tatiana Kulakovskaya
Appl. Microbiol.2025, 5(4), 109;https://doi.org/10.3390/applmicrobiol5040109 
(registering DOI)

11 October 2025

Mutant yeast strains with altered sensitivity to heavy metals are crucial for revealing the mechanisms of metal absorption and detoxification, as well as for bioremediation of these pollutants. Here, we show that a knockout of the PHO87 gene encoding...

  • Article
  • Open Access
218 Views
25 Pages

Survey of Thirteen Novel Pseudomonas putida Bacteriophages

  • Simon Anderson,
  • Rachel Persinger,
  • Akaash Patel,
  • Easton Rupe,
  • Johnathan Osu,
  • Katherine I. Cooper,
  • Susan M. Lehman,
  • Rohit Kongari,
  • James D. Jaryenneh and
  • Catherine M. Mageeney
  • + 2 authors

Bacteriophages have been widely investigated as a promising treatment of food, medical equipment, and humans colonized by antibiotic-resistant bacteria. Phages pose particular interest in combating those bacteria which form biofilms, such as the medi...

  • Opinion
  • Open Access
294 Views
8 Pages

The prevalence of probiotic-labeled products with no evidence of improved health outcomes associated with their consumption has perturbed both the trust of clinicians and the public perception of microbial therapeutics. While probiotics are clearly d...

  • Article
  • Open Access
212 Views
15 Pages

US food regulatory agencies have adopted a preference for researchers and testing labs to use ‘acid-adapted challenge cultures’ when performing inoculated validation studies of food processes that involve acidic treatments to accustom the...

  • Article
  • Open Access
236 Views
21 Pages

BioLumCity: 3D-Printed Bioluminescent Urban Tiles Employing Aliivibrio fischeri Bioink as Passive Urban Light

  • Yomna K. Abdallah,
  • Alberto T. Estévez,
  • Aranzazu Balfagón Martin and
  • Marta Serra Soriano

Integrating bioluminescent organisms as passive lighting sources in the built environment is currently a hot topic. However, there are several limitations facing the implementation and up-scaling of these naturally bioluminescent organisms in the bui...

  • Communication
  • Open Access
249 Views
8 Pages

Brucella Diagnostics in Endemic Areas: Evaluation of Point-of-Care Kits and the Need for Alternative Diagnostic Tests

  • Aggrey Keya,
  • Pauline Gitonga,
  • Daniel Wanjohi,
  • Esther Lemarkoko,
  • Joseph Sankok,
  • Brian Ogoti,
  • Angela Bosco-Lauth,
  • Marybeth Maritim,
  • George Gitao and
  • Joshua Onono
  • + 2 authors

Brucellosis is a significant public health challenge in Kenya, particularly in pastoralist communities where the disease is endemic. Reliable and accurate point-of-care diagnostics are essential for timely case identification and effective disease ma...

  • Editorial
  • Open Access
464 Views
6 Pages

While pathogenic microbes, such as Yersinia pestis, Mycobacterium tuberculosis, Clostridium tetani, influenza A virus, and many others, have historically been the focus of scientific attention due to their role in causing severe diseases, beneficial...

  • Article
  • Open Access
322 Views
23 Pages

Development and Evaluation of an Exogenous Bioaugmentation Framework Using an Immobilized Mixed Bacterial Consortium for the Remediation of Hydrocarbon-Contaminated Soils

  • Emerance Jessica Claire D’Assise Goma-Tchimbakala,
  • Ilaria Pietrini,
  • Alessandro Conte,
  • Neria Costa and
  • Stefano Paolo Corgnati

Improving the quality of oil-contaminated soils remains a critical challenge, and bioaugmentation using allochthonous bacteria offers promising perspectives. This study proposes a framework for exogenous bioaugmentation using a bacterial consortium,...

  • Review
  • Open Access
835 Views
23 Pages

Streptococcus thermophilus is a Gram-positive, homofermentative lactic acid bacterium classified within the Firmicutes phylum, recognized for its probiotic properties and significant role in promoting human health. This review consolidates existing u...

  • Article
  • Open Access
357 Views
13 Pages

Asparaginase (ASNase) is an important enzyme used to treat acute lymphoblastic leukemia. However, the clinical use of the currently available ASNases is limited because of their associated side effects. One of the major reasons for these adverse effe...