Special Issue "Actinomycetes: The Antibiotics Producers"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (28 February 2018).
Interests: antibiotics; glycopeptides; genome mining; metabolic engineering; precursor supply; self-resistance; chelating agent; Amycolatopsis
Interests: antibiotics; Streptomycetes; biosynthesis; silent gene cluster; genome mining; genetic engineering; synthetic biology; regulation; overproduction; streptogramins
Special Issues and Collections in MDPI journals
Actinomycetes are well-known as an inexhaustible source for antibiotics. Most of the identified antimicrobials today have been isolated from the genus Streptomyces, however, not the least, next-generation sequencing techniques, together with genome mining analyses, revealed that there are far more potential antibiotic producers out in nature, also belonging to other genera of the order of Actinomycetales. Some of them have just not been identified because they live in extreme or rare habitats, others have not been made accessible so far due to the impossibility of cultivating them in a lab. Today, around 75 years after Selman Waksman introduced the genus of Streptomyces for the first time, these bacteria still are a treasure chest for the identification of novel antibiotics. This is even more important since new antimicrobials are urgently needed, as resistances of live-threatening pathogenic bacteria are rising. Novel cultivation strategies, elaborated screening techniques, new genetic manipulation tools, more insights in physiological aspects of actinobacterial life style but also knowledge on new secondary metabolite biosynthetic pathways may open up a new era of antibiotic drug discovery. In the Special Issue of “Actinomycetes: The Antibiotics Producers” we will highlight the latest research findings in the field.
Dr. Evi Stegmann
Dr. Yvonne Mast
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- secondary metabolites
- natural products
- genetic engineering
- genome mining
- extreme habitats