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Special Issue "Drugs for Superbugs: Antibiotic Discovery, Modes of Action and Mechanisms of Resistance"
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: 31 May 2023 | Viewed by 9627
Special Issue Editors
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Interests: antimicrobial agents; emerging antimicrobial strategies; antimicrobial resistance; biofilms; plant secondary metabolites
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Interests: mycotoxins; fungal metabolites; antimicrobial; anticancer; antinflammatory; antioxidant
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Topical Collection in Toxins: Leading Opinions (Closed)
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Topical Collection in Toxins: Editorial Board Members’ Collection Series: Fungal Metabolites: From Toxins to Therapeutics
Special Issue in Antibiotics: Editorial Board Members' Collection Series: Structural Aspects of AMPs and Antimicrobials
Special Issue Information
Antibiotics have proven to be powerful drugs for the control of infectious diseases caused by bacteria and remain one of the most significant discoveries in modern medicine. The development of antibiotic resistance is the consequence of decades of constant selective pressure via the underuse, overuse and misuse of therapeutic molecules, which highly benefit the extraordinary genetic capacities of bacteria. The remarkable plasticity of microorganism genomes in addition to the capacity to acquire and transmit genetic determinants of resistance are conserved evolution strategies and have exacerbated the worldwide resistance problem.
The quest for new antibacterials to overcome resistance problems has long been a top research priority. However, scientific difficulties and low financial returns have led to the withdrawal of many pharmaceutical companies from antibiotic R&D. On the other hand, academia is still highly prolific in R&D on antibiotics discovery from the most diverse sources, their modes of action and mechanisms of resistance.
It is our aim that this event can provide an opportunity to representatives of academia, industry and health services to discuss and advance our current knowledge on how to control microorganisms.
We welcome discussions of the following topics at the event:
- Drug discovery and development—from natural sources to (bio)synthesis;
- Drug repurposing for antibacterial therapy;
- Antibiotics recycling and resistance modifiers;
- Virtual screening;
- Susceptibility testing;
- Mechanisms of action;
- Pharmacological parameters, including in vitro or in vivo modelling studies;
- Novel delivery systems for antibacterials;
- Mechanisms of resistance—from natural to acquired;
- Omics in antibacterial action and resistance;
- Epidemiology and the emergence of antibiotic resistant pathogens;
- Clinical trials and clinical cases of antibiotic resistance;
- Antibacterials and interfaces.
This Special Issue welcomes both selected papers from the ECA 2022 and the papers that promote and advance the exciting and rapidly changing field.
Submitted contributions will be subjected to peer review and, upon acceptance, will be published with the aim of rapidly and widely disseminating research results, developments, and applications.
We look forward to receiving your contributions.
Dr. Manuel Simões
Dr. Marc Maresca
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.