We are pleased to invite you to read the following 15 most highly cited papers published on the topic of disease biomarkers in the Journal of Personalized Medicine (JPM, ISSN: 2075-4426) in 2022.

1. “Emerging Biomarkers for Early Detection of Chronic Kidney Disease”
by Maja Mizdrak, Marko Kumrić, Tina Tičinović Kurir and Joško Božić
J. Pers. Med. 2022, 12(4), 548; https://doi.org/10.3390/jpm12040548
Available online: https://www.mdpi.com/2075-4426/12/4/548

2. “Sensory Ion Channel Candidates Inform on the Clinical Course of Pancreatic Cancer and Present Potential Targets for Repurposing of FDA-Approved Agents”
by Wenjie Shi, Chen Li, Thomas Wartmann, Christoph Kahlert, Renfei Du, Aristotelis Perrakis, Thomas Brunner, Roland S. Croner and Ulf D. Kahlert
J. Pers. Med. 2022, 12(3), 478; https://doi.org/10.3390/jpm12030478
Available online: https://www.mdpi.com/2075-4426/12/3/478

3. “Multi-Omics Profiling Approach to Asthma: An Evolving Paradigm”
by Yadu Gautam, Elisabet Johansson and Tesfaye B. Mersha
J. Pers. Med. 2022, 12(1), 66; https://doi.org/10.3390/jpm12010066
Available online: https://www.mdpi.com/2075-4426/12/1/66

4. “Deep Learning-Based Diagnosis of Alzheimer’s Disease”
by Tausifa Jan Saleem, Syed Rameem Zahra, Fan Wu, Ahmed Alwakeel, Mohammed Alwakeel, Fathe Jeribi and Mohammad Hijji
J. Pers. Med. 2022, 12(5), 815; https://doi.org/10.3390/jpm12050815
Available online: https://www.mdpi.com/2075-4426/12/5/815

5. “The Importance of SNPs at miRNA Binding Sites as Biomarkers of Gastric and Colorectal Cancers: A Systematic Review”
by Fatemeh Hajibabaie, Navid Abedpoor, Nazanin Assareh, Mohammad Amin Tabatabaiefar, Laleh Shariati and Ali Zarrabi
J. Pers. Med. 2022, 12(3), 456; https://doi.org/10.3390/jpm12030456
Available online: https://www.mdpi.com/2075-4426/12/3/456

6. “Dysregulated miRNAs as Biomarkers and Therapeutical Targets in Neurodegenerative Diseases”
by Giulia Gentile, Giovanna Morello, Valentina La Cognata, Maria Guarnaccia, Francesca Luisa Conforti and Sebastiano Cavallaro
J. Pers. Med. 2022, 12(5), 770; https://doi.org/10.3390/jpm12050770
Available online: https://www.mdpi.com/2075-4426/12/5/770

7. “Machine Learning-Assisted FTIR Analysis of Circulating Extracellular Vesicles for Cancer Liquid Biopsy”
by Riccardo Di Santo, Maria Vaccaro, Sabrina Romanò, Flavio Di Giacinto, Massimiliano Papi, Gian Ludovico Rapaccini, Marco De Spirito, Luca Miele, Umberto Basile and Gabriele Ciasca
J. Pers. Med. 2022, 12(6), 949; https://doi.org/10.3390/jpm12060949
Available online: https://www.mdpi.com/2075-4426/12/6/949

8. “CDK1 and HSP90AA1 Appear as the Novel Regulatory Genes in Non-Small Cell Lung Cancer: A Bioinformatics Approach”
by Nirjhar Bhattacharyya, Samriddhi Gupta, Shubham Sharma, Aman Soni, Sali Abubaker Bagabir, Malini Bhattacharyya, Atreyee Mukherjee, Atiah H. Almalki, Mustfa F. Alkhanani, Shafiul Haque et al.
J. Pers. Med. 2022, 12(3), 393; https://doi.org/10.3390/jpm12030393
Available online: https://www.mdpi.com/2075-4426/12/3/393

9. “Current Status, Issues and Future Prospects of Personalized Medicine for Each Disease”
by Yuichi Yamamoto, Norihiro Kanayama, Yusuke Nakayama and Nobuko Matsushima
J. Pers. Med. 2022, 12(3), 444; https://doi.org/10.3390/jpm12030444
Available online: https://www.mdpi.com/2075-4426/12/3/444

10. “miR-155: A Potential Biomarker for Predicting Mortality in COVID-19 Patients”
by Reut Kassif-Lerner, Keren Zloto, Nadav Rubin, Keren Asraf, Ram Doolman, Gidi Paret and Yael Nevo-Caspi
J. Pers. Med. 2022, 12(2), 324; https://doi.org/10.3390/jpm12020324
Available online: https://www.mdpi.com/2075-4426/12/2/324

11. “Olfaction Recovery following Dupilumab Is Independent of Nasal Polyp Reduction in CRSwNP”
by Elena Cantone, Eugenio De Corso, Filippo Ricciardiello, Claudio Di Nola, Giusi Grimaldi, Viviana Allocca and Gaetano Motta
J. Pers. Med. 2022, 12(8), 1215; https://doi.org/10.3390/jpm12081215
Available online: https://www.mdpi.com/2075-4426/12/8/1215

12. “Use of Circulating Tumour DNA (ctDNA) for Measurement of Therapy Predictive Biomarkers in Patients with Cancer”
by Michael J. Duffy and John Crown
J. Pers. Med. 2022, 12(1), 99; https://doi.org/10.3390/jpm12010099
Available online: https://www.mdpi.com/2075-4426/12/1/99

13. “Theratyping of the Rare CFTR Variants E193K and R334W in Rectal Organoid-Derived Epithelial Monolayers”
by Fabiana Ciciriello, Marcel J. C. Bijvelds, Federico Alghisi, Kelly F. Meijsen, Luca Cristiani, Claudio Sorio, Paola Melotti, Alessandro G. Fiocchi, Vincenzina Lucidi and Hugo R. De Jonge
J. Pers. Med. 2022, 12(4), 632; https://doi.org/10.3390/jpm12040632
Available online: https://www.mdpi.com/2075-4426/12/4/632

14. “Personalized Management of Myocarditis and Inflammatory Cardiomyopathy in Clinical Practice”
by Agata Tymińska, Krzysztof Ozierański, Aleksandra Skwarek, Agnieszka Kapłon-Cieślicka, Anna Baritussio, Marcin Grabowski, Renzo Marcolongo and Alida LP Caforio
J. Pers. Med. 2022, 12(2), 183; https://doi.org/10.3390/jpm12020183
Available online: https://www.mdpi.com/2075-4426/12/2/183

15. “From Skin Barrier Dysfunction to Systemic Impact of Atopic Dermatitis: Implications for a Precision Approach in Dermocosmetics and Medicine”
by Laura Maintz, Thomas Bieber, Helen D. Simpson and Anne-Laure Demessant-Flavigny
J. Pers. Med. 2022, 12(6), 893; https://doi.org/10.3390/jpm12060893
Available online: https://www.mdpi.com/2075-4426/12/6/893