Cells | Explore Papers and Special Issues on Pluripotent Stem Cells

We are delighted to share a collection of papers on pluripotent stem cells published from 2024 to 2025 in Cells (ISSN 2073-4409).

In addition, we would like to highlight several Special Issues related to this topic that are currently open for submission.

1. “Brain Organoids and Assembloids—From Disease Modeling to Drug Discovery”
by Aderonke O. Ajongbolo and Sigrid A. Langhans
Cells 2025, 14(11), 842; https://doi.org/10.3390/cells14110842
Available online: https://www.mdpi.com/2073-4409/14/11/842

2. “Induced Pluripotent Stem Cells-Based Regenerative Therapies in Treating Human Aging-Related Functional Decline and Diseases”
by Peijie Yu, Bin Liu, Cheng Dong and Yun Chang
Cells 2025, 14(8), 619; https://doi.org/10.3390/cells14080619
Available online: https://www.mdpi.com/2073-4409/14/8/619

3. “Interconversion of Cancer Cells and Induced Pluripotent Stem Cells”
by Drishty B. Sarker, Yu Xue, Faiza Mahmud, Jonathan A. Jocelyn and Qing-Xiang Amy Sang
Cells 2024, 13(2), 125; https://doi.org/10.3390/cells13020125
Available online: https://www.mdpi.com/2073-4409/13/2/125

4. “Current Advances and Future Directions of Pluripotent Stem Cells-Derived Engineered Heart Tissue for Treatment of Cardiovascular Diseases”
by Xingyu He, Angela Good, Wael Kalou, Waqas Ahmad, Suchandrima Dutta, Sophie Chen, Charles Noah Lin, Karthickeyan Chella Krishnan, Yanbo Fan, Wei Huang et al.
Cells 2024, 13(24), 2098; https://doi.org/10.3390/cells13242098
Available online: https://www.mdpi.com/2073-4409/13/24/2098

5. “Human-Induced Pluripotent Stem Cells (iPSCs) for Disease Modeling and Insulin Target Cell Regeneration in the Treatment of Insulin Resistance: A Review”
by Sama Thiab, Juberiya M. Azeez, Alekya Anala, Moksha Nanda, Somieya Khan, Alexandra E. Butler and Manjula Nandakumar
Cells 2025, 14(15), 1188; https://doi.org/10.3390/cells14151188
Available online: https://www.mdpi.com/2073-4409/14/15/1188

6. “Age-Related Neurodegenerative Diseases: A Stem Cell’s Perspective”
by Belén Calvo, Pierre Schembri-Wismayer and María Beatriz Durán-Alons
Cells 2025, 14(5), 347; https://doi.org/10.3390/cells14050347
Available online: https://www.mdpi.com/2073-4409/14/5/347

7. “Hypoimmunogenic Human iPSCs for Repair and Regeneration in the CNS”
by Haiwei Zhang, Hongxia Zhou, Xugang Xia, Qilin Cao and Ying Liu
Cells 2025, 14(16), 1248; https://doi.org/10.3390/cells14161248
Available online: https://www.mdpi.com/2073-4409/14/16/1248

8. “Updated Applications of Stem Cells in Hypoplastic Left Heart Syndrome”
by Rui Xiao, Haleema Darr, Zarif Khan and Qingzhong Xiao
Cells 2025, 14(17), 1396; https://doi.org/10.3390/cells14171396
Available online: https://www.mdpi.com/2073-4409/14/17/1396

9. “Neonicotinoid Pesticides Affect Developing Neurons in Experimental Mouse Models and in Human Induced Pluripotent Stem Cell (iPSC)-Derived Neural Cultures and Organoids”
by Alessandro Mariani, Davide Comolli, Roberto Fanelli, Gianluigi Forloni and Massimiliano De Paola
Cells 2024, 13(15), 1295; https://doi.org/10.3390/cells13151295
Available online: https://www.mdpi.com/2073-4409/13/15/1295

10. “Induced Pluripotent Stem Cell-Derived Exosomes Promote Peripheral Nerve Regeneration in a Rat Sciatic Nerve Crush Injury Model: A Safety and Efficacy Study”
by Fatima Aldali, Yujie Yang, Chunchu Deng, Xiangling Li, Xiaojian Cao, Jia Xu, Yajie Li, Jianlin Ding and Hong Chen
Cells 2025, 14(7), 529; https://doi.org/10.3390/cells14070529
Available online: https://www.mdpi.com/2073-4409/14/7/529

11. “Human-Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Showed Neuronal Differentiation, Neurite Extension, and Formation of Synaptic Structures in Rodent Ischemic Stroke Brains”
by Yonehiro Kanemura, Atsuyo Yamamoto, Asako Katsuma, Hayato Fukusumi, Tomoko Shofuda, Daisuke Kanematsu, Yukako Handa, Miho Sumida, Ema Yoshioka, Yutaka Mine et al.
Cells 2024, 13(8), 671; https://doi.org/10.3390/cells13080671
Available online: https://www.mdpi.com/2073-4409/13/8/671

12. “Enhancing Maturation and Translatability of Human Pluripotent Stem Cell-Derived Cardiomyocytes through a Novel Medium Containing Acetyl-CoA Carboxylase 2 Inhibitor”
by Cláudia Correia, Jonas Christoffersson, Sandra Tejedor, Saïd El-Haou, Meztli Matadamas-Guzman, Syam Nair, Pierre Dönnes, Gentian Musa, Mattias Rohman, Monika Sundqvist et al.
Cells 2024, 13(16), 1339; https://doi.org/10.3390/cells13161339
Available online: https://www.mdpi.com/2073-4409/13/16/1339

13. “Generation of Individualized, Standardized, and Electrically Synchronized Human Midbrain Organoids”
by Sanae El Harane, Bahareh Nazari, Nadia El Harane, Manon Locatelli, Bochra Zidi, Stéphane Durual, Abderrahim Karmime, Florence Ravier, Adrien Roux, Luc Stoppini et al.
Cells 2025, 14(15), 1211; https://doi.org/10.3390/cells14151211
Available online: https://www.mdpi.com/2073-4409/14/15/1211

14. “Electrophysiological Phenotyping of hiPSC-Derived Atrial Cardiomyocytes Using Automated Patch-Clamp: A Platform for Studying Atrial Inherited Arrhythmias”
by Verónica Jiménez-Sábado, Hosna Babini, Peter C. Ruben, Eric A. Accili, Thomas W. Claydon, Leif Hove-Madsen and Glen F. Tibbits
Cells 2025, 14(24), 1941; https://doi.org/10.3390/cells14241941
Available online: https://www.mdpi.com/2073-4409/14/24/1941

15. “Transcriptomic Profiling of iPS Cell-Derived Hepatocyte-like Cells Reveals Their Close Similarity to Primary Liver Hepatocytes”
by Saqlain Suleman, Sharmin Alhaque, Andrew Guo, Aaron Zhang, Serena Fawaz, Stefany Perera, Mohammad S. Khalifa, Hassan Rashidi, David C. Hay and Michael Themis
Cells 2025, 14(12), 925; https://doi.org/10.3390/cells14120925
Available online: https://www.mdpi.com/2073-4409/14/12/925

16. “Targeting Diabetic Retinopathy with Human iPSC-Derived Vascular Reparative Cells in a Type 2 Diabetes Model”
by Sergio Li Calzi, Dibyendu Chakraborty, Ping Hu, Ram Prasad, Yvonne Adu-Rutledge, Cristiano Vieira, Fadeela Sheini, Michael E. Boulton, Mervin C. Yoder, Changde Cheng et al.
Cells 2025, 14(17), 1352; https://doi.org/10.3390/cells14171352
Available online: https://www.mdpi.com/2073-4409/14/17/1352

Relevant Special Issues:

“Recent Advances in Novel Cell and Gene Therapies for the Treatment of Immune Diseases”
Guest Editor: Dr. Qingdong Guan
Deadline for manuscript submissions: 15 November 2026

“Advances in Human Pluripotent Stem Cells”
Guest Editors: Dr. Peggy Arthur, Dr. Sangeetha Kandoi, and Dr. Nagavendra Kommineni
Deadline for manuscript submissions: 25 January 2027