
Cancers | Highly Cited Papers Published in 2024–2025 in Web of Science (IV)
Cancers (ISSN 2072-6694) is a peer-reviewed, open access oncology journal published semimonthly online, with 17 Sections open for submissions. We are pleased to recommend a selection of highly cited papers published in the journal in 2024–2025, which have earned Highly Cited Paper recognition from Web of Science. These papers also demonstrate strong view and download metrics, reflecting their broad impact in the field of oncology. We extend our sincere gratitude to all the authors for their outstanding contributions, innovative research, and continued efforts to advance cancer research. We hope these papers, covering a wide range of topics, will offer you valuable insights and inspiration.
“Molecular Subtypes and Mechanisms of Breast Cancer: Precision Medicine Approaches for Targeted Therapies”
by Eduarda Carvalho, Sule Canberk, Fernando Schmitt and Nuno Vale
Cancers 2025, 17(7), 1102; https://doi.org/10.3390/cancers17071102
Available online: https://www.mdpi.com/2072-6694/17/7/1102
“From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial Cancer”
by Thulo Molefi, Lloyd Mabonga, Rodney Hull, Motshedisi Sebitloane and Zodwa Dlamini
Cancers 2025, 17(2), 320; https://doi.org/10.3390/cancers17020320
Available online: https://www.mdpi.com/2072-6694/17/2/320
“The Role of KRAS Mutations in Colorectal Cancer: Biological Insights, Clinical Implications, and Future Therapeutic Perspectives”
by Mitsunobu Takeda, Shoma Yoshida, Takuya Inoue, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, Takayuki Ogino, Norikatsu Miyoshi, Mamoru Uemura, Hirofumi Yamamoto et al.
Cancers 2025, 17(3), 428; https://doi.org/10.3390/cancers17030428
Available online: https://www.mdpi.com/2072-6694/17/3/428
“Claudin 18.2 as a New Biomarker in Gastric Cancer—What Should We Know?”
by Maria Cecília Mathias-Machado, Victor Hugo Fonseca de Jesus, Alexandre Jácome, Mauro Daniel Donadio, Marcelo Porfirio Sunagua Aruquipa, João Fogacci, Renato Guerino Cunha, Leonard Medeiros da Silva and Renata D’Alpino Peixoto
Cancers 2024, 16(3), 679; https://doi.org/10.3390/cancers16030679
Available online: https://www.mdpi.com/2072-6694/16/3/679
“The Role of Circulating Tumor Cells as a Liquid Biopsy for Cancer: Advances, Biology, Technical Challenges, and Clinical Relevance”
by Tyler A. Allen
Cancers 2024, 16(7), 1377; https://doi.org/10.3390/cancers16071377
Available online: https://www.mdpi.com/2072-6694/16/7/1377
“Exosomes in Precision Oncology and Beyond: From Bench to Bedside in Diagnostics and Therapeutics”
by Emile Youssef, Dannelle Palmer, Brandon Fletcher and Renee Vaughn
Cancers 2025, 17(6), 940; https://doi.org/10.3390/cancers17060940
Available online: https://www.mdpi.com/2072-6694/17/6/940
“AI Model for Predicting Anti-PD1 Response in Melanoma Using Multi-Omics Biomarkers”
by Axel Gschwind and Stephan Ossowski
Cancers 2025, 17(5), 714; https://doi.org/10.3390/cancers17050714
Available online: https://www.mdpi.com/2072-6694/17/5/714
“Prognostic Value of PLR, SIRI, PIV, SII, and NLR in Non-Muscle Invasive Bladder Cancer: Can Inflammatory Factors Influence Pathogenesis and Outcomes?”
by Francesco Pio Bizzarri, Marco Campetella, Pierluigi Russo, Giuseppe Palermo, Seyed Koosha Moosavi, Francesco Rossi, Lorenzo D’Amico, Antonio Cretì, Filippo Gavi, Enrico Panio et al.
Cancers 2025, 17(13), 2189; https://doi.org/10.3390/cancers17132189
Available online: https://www.mdpi.com/2072-6694/17/13/2189
“Prognostic Value of Neutrophil-to-Eosinophil Ratio (NER) in Cancer: A Systematic Review and Meta-Analysis”
by Taha Koray Sahin, Ruveyda Ayasun, Alessandro Rizzo and Deniz Can Guven
Cancers 2024, 16(21), 3689; https://doi.org/10.3390/cancers16213689
Available online: https://www.mdpi.com/2072-6694/16/21/3689
“Prognostic Significance of the Royal Marsden Hospital (RMH) Score in Patients with Cancer: A Systematic Review and Meta-Analysis”
by Taha Koray Sahin, Alessandro Rizzo, Sercan Aksoy and Deniz Can Guven
Cancers 2024, 16(10), 1835; https://doi.org/10.3390/cancers16101835
Available online: https://www.mdpi.com/2072-6694/16/10/1835
“Harnessing Artificial Intelligence to Enhance Global Breast Cancer Care: A Scoping Review of Applications, Outcomes, and Challenges”
by Jolene Li Ling Chia, George Shiyao He, Kee Yuen Ngiam, Mikael Hartman, Qin Xiang Ng and Serene Si Ning Goh
Cancers 2025, 17(2), 197; https://doi.org/10.3390/cancers17020197
Available online: https://www.mdpi.com/2072-6694/17/2/197
“Exploring Artificial Intelligence Biases in Predictive Models for Cancer Diagnosis”
by Aref Smiley, C. Mahony Reategui-Rivera, David Villarreal-Zegarra, Stefan Escobar-Agreda and Joseph Finkelstein
Cancers 2025, 17(3), 407; https://doi.org/10.3390/cancers17030407
Available online: https://www.mdpi.com/2072-6694/17/3/407
“Artificial Intelligence for Neuroimaging in Pediatric Cancer”
by Josue Luiz Dalboni da Rocha, Jesyin Lai, Pankaj Pandey, Phyu Sin M. Myat, Zachary Loschinskey, Asim K. Bag and Ranganatha Sitaram
Cancers 2025, 17(4), 622; https://doi.org/10.3390/cancers17040622
Available online: https://www.mdpi.com/2072-6694/17/4/622
“Advanced Brain Tumor Classification in MR Images Using Transfer Learning and Pre-Trained Deep CNN Models”
by Rukiye Disci, Fatih Gurcan and Ahmet Soylu
Cancers 2025, 17(1), 121; https://doi.org/10.3390/cancers17010121
Available online: https://www.mdpi.com/2072-6694/17/1/121
“Clinical Applications of Artificial Intelligence in Medical Imaging and Image Processing—A Review”
by Rafał Obuchowicz, Michał Strzelecki and Adam Piórkowski
Cancers 2024, 16(10), 1870; https://doi.org/10.3390/cancers16101870
Available online: https://www.mdpi.com/2072-6694/16/10/1870
“Exploring Experimental Models of Colorectal Cancer: A Critical Appraisal from 2D Cell Systems to Organoids, Humanized Mouse Avatars, Organ-on-Chip, CRISPR Engineering, and AI-Driven Platforms—Challenges and Opportunities for Translational Precision Oncology”
by Ahad Al-Kabani, Bintul Huda, Jewel Haddad, Maryam Yousuf, Farida Bhurka, Faika Ajaz, Rajashree Patnaik, Shirin Jannati and Yajnavalka Banerjee
Cancers 2025, 17(13), 2163; https://doi.org/10.3390/cancers17132163
Available online: https://www.mdpi.com/2072-6694/17/13/2163
“Multimodal Imaging of Osteosarcoma: From First Diagnosis to Radiomics”
by Maurizio Cè, Michaela Cellina, Thirapapha Ueanukul, Gianpaolo Carrafiello, Rawee Manatrakul, Phatthawit Tangkittithaworn, Suphaneewan Jaovisidha, Praman Fuangfa and Donald Resnick
Cancers 2025, 17(4), 599; https://doi.org/10.3390/cancers17040599
Available online: https://www.mdpi.com/2072-6694/17/4/599
“Adaptive Radiotherapy: Next-Generation Radiotherapy”
by Olga Maria Dona Lemus, Minsong Cao, Bin Cai, Michael Cummings and Dandan Zheng
Cancers 2024, 16(6), 1206; https://doi.org/10.3390/cancers16061206
Available online: https://www.mdpi.com/2072-6694/16/6/1206
You can browse more high-impact research by visiting our Most Cited & Viewed section, where all full-text articles are freely accessible.
We invite you to read these papers and consider Cancers for your next manuscript submission. To learn more about our journal and submit your research, please visit: https://www.mdpi.com/journal/cancers.
Cancers Editorial Office