Myeloma and Leukemia—Challenges and Current Treatment Options: 2nd Edition

Dear Colleagues,

This Topic is the second edition of the collection “Myeloma and Leukemia—Challenges and Current Treatment Options”, available at https://www.mdpi.com/topics/LCACTO.

After years of stagnation in the field, in recent years, we have entered into a new era in multiple myeloma and acute leukemia therapy with the discovery of many novel agents. This was due to better knowledge of the biology of the diseases, and of the pathogenesis-related pathways, with the advent of new combinations of drugs and new therapy development, together with an improved understanding of the immune system, resulting in great progress in the development of immune therapies for the treatment of patients, including monoclonal and bispecific antibodies, and CAR-T cell approaches. The numerous ongoing trials evaluating these new opportunities, also considering real-life experiences, are helping to confirm the efficacy and tolerability of these drugs in daily clinical practice. This Topic aims to focus on novel agents and their combinations. Focus will be placed on the efficacy of novel drugs and promising combination approaches to further improve outcomes in the treatment of patients with multiple myeloma and acute leukemia. 

We welcome the submission of original research articles, reviews, interesting case reports, and interim data of clinical trials.

Dr. Giovanni Martinelli
Dr. Claudio Cerchione
Topic Editors