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Journal of Respiration, Volume 6, Issue 3

2026 September - 12 articles

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Articles (12)

  • Article
  • Open Access
789 Views
18 Pages

10 September 2026

Background: Chronic cough is a major determinant of impaired quality of life and recurrent exacerbations in bronchiectasis. The BEAT-COUGH Study evaluated the effectiveness of adjunctive oral erdosteine plus nebulized amikacin during acute exacerbati...

(This article belongs to the Special Issue Bronchiectasis: Advancing into the Future)
  • Article
  • Open Access
524 Views
21 Pages

Incremental PEEP Increases Peak Inspiratory Flow Disproportionately to Inspiratory Pressure Swing Across Respiratory Exposure Groups in Spontaneously Breathing Volunteers

  • Gaetano Gazzè,
  • Martina Caronna,
  • Emanuele Rollo,
  • Valentina Ceccarelli and ,
  • Sara Orlando,
  • Marco Covotta and
  • Giulia Torregiani
  • + 2 authors+ 0 author

7 September 2026

Background: How spontaneously breathing individuals modulate inspiratory pressure and peak inspiratory flow (PIF) during incremental positive end-expiratory pressure (PEEP) loading, and whether this differs across respiratory exposure groups, are inc...

  • Review
  • Open Access
1,591 Views
22 Pages

2 September 2026

Interstitial lung disease (ILD) is a frequent manifestation and a leading cause of morbidity and mortality in idiopathic inflammatory myopathies (IIM), particularly in antisynthetase syndrome (ASyS) and anti-melanoma differentiation-associated protei...

(This article belongs to the Special Issue Advances in Interstitial Lung Diseases: From Diagnosis to Treatment)
  • Review
  • Open Access
1,259 Views
36 Pages

19 August 2026

Cellular senescence is one of the major risk factors for the onset and progression of chronic pulmonary diseases. Cellular senescence can be induced by diverse stressors, including genotoxic damage, oncogenic signaling, and therapeutic interventions....

(This article belongs to the Collection Feature Papers in Journal of Respiration)
  • Case Report
  • Open Access
925 Views
14 Pages

15 August 2026

Background: Acute bronchiolitis is among the most common causes of lower-respiratory-tract infection in infancy and remains a clinically heterogeneous syndrome. Current international guidelines recommend supportive management and generally discourage...

  • Review
  • Open Access
847 Views
22 Pages

Pulmonary Involvement in Primary Sjögren’s Syndrome: Interstitial Lung Disease Phenotypes and Diagnostic Challenges

  • Ivanna N. Ferrín Yépez,
  • Killen H. Briones-Claudett,
  • Anahi D. Briones-Zamora and
  • Killen H. Briones-Zamora

6 August 2026

Pulmonary involvement in primary Sjögren’s syndrome (pSS) is common and exhibits significant clinical heterogeneity, particularly in cases where interstitial lung disease (pSS-ILD) develops. Reported variability in prevalence, radiologic p...

  • Systematic Review
  • Open Access
660 Views
19 Pages

Pulmonary Vasodilators in COPD-Associated Pulmonary Hypertension: An Updated Meta-Analysis of Randomized Evidence

  • Micah Nnabuko Okwah,
  • Ihesiulo Alozie,
  • Jeremiah Adepoju,
  • Itua Abhulimen and ,
  • Obinna Adolalom,
  • Oluwasegun Oladeji,
  • Olaitan Akinrele,
  • Ihesiulo Chigozie,
  • Anim Asif and
  • Ismaila Ajayi Yusuf
  • + 9 authors+ 4 authors

6 August 2026

Background: Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease (COPD), termed COPD-associated pulmonary hypertension (COPD-PH), and is associated with worse clinical outcomes. The efficacy and safety of pulm...

(This article belongs to the Special Issue Pulmonary Hypertension: New Insights and Recent Advances)
  • Case Report
  • Open Access
853 Views
9 Pages

Rituximab-Induced Lung Disease Presenting as Organizing Pneumonia in a Patient with Stable Rheumatoid Arthritis

  • Sikandar Khan,
  • Ofek Raviv,
  • Brian Foster,
  • Ana Suarez-Gonzalez and
  • Roger A Alvarez

1 August 2026

Rituximab-induced lung disease (R-ILD) is a rare but potentially serious complication most commonly reported in patients receiving rituximab as part of combination chemotherapy for hematologic malignancies. Pulmonary toxicity associated with rituxima...

  • Article
  • Open Access
1,031 Views
10 Pages

The Impact of Breathing Pattern (Nasal vs. Oral) on the Severity of Obstructive Sleep Apnea

  • Mirjana Grebenar Čerkez,
  • Darija Birtić,
  • Anamarija Šestak,
  • Jelena Šarić Jurić and ,
  • Stjepan Jurić,
  • Marta Petek Vinković,
  • Mirjana Čubra and
  • Jelena Kovačević
  • + 3 authors+ 0 author

21 July 2026

Background: Nasal obstruction has been implicated in the pathophysiology of obstructive sleep apnoea (OSA), potentially contributing to upper airway instability and impaired breathing during sleep. However, its precise role in determining disease sev...

  • Article
  • Open Access
690 Views
21 Pages

Exploring New Therapeutic Targets in NSCLC: Unraveling the Interplay Between NTRK and PD-L1 Expression

  • Jair Gutierrez-Herrera,
  • Maria Angeles Montero-Fernandez,
  • Georgia Kokaraki,
  • Luigi De Petris and ,
  • Raul Maia Falcão,
  • Ricardo Guijarro,
  • Simon Ekman and
  • Cristian Ortiz-Villalón
  • + 3 authors+ 0 author

15 July 2026

Background: Precision medicine has introduced immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) as key therapies for lung cancer. However, the interaction between PD-L1 expression and NTRK rearrangements in non-small cell lung...

(This article belongs to the Collection Feature Papers in Journal of Respiration)
  • Review
  • Open Access
1,576 Views
42 Pages

10 July 2026

Background: Obstructive sleep apnoea (OSA) is increasingly associated with earlier onset and accelerated trajectories of neurodegenerative change. Mechanistically, this relationship is thought to reflect convergent pathways spanning intermittent hypo...

  • Guidelines
  • Open Access
2,357 Views
35 Pages

S2k Guideline: Breathing, Respiratory Support and Ventilation in Acute and Chronic Spinal Cord Injury

  • Anja M. Raab,
  • Oswald Marcus,
  • Sören Tiedemann,
  • Marc Landscheid and ,
  • Sven Hirschfeld,
  • Guido Ketter,
  • Maria-Cristina Hallwachs and
  • Franz Michel
  • + 3 authors+ 0 author

Background/Objectives: Spinal cord injury (SCI) frequently leads to impaired respiratory function and increased pneumonia risk due to reduced respiratory muscle strength, altered thoracic compliance, autonomic dysregulation, and diaphragm displacemen...

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J. Respir. - ISSN 2673-527X