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Diabetology, Volume 6, Issue 10

2025 October - 21 articles

Cover Story: Type 2 diabetes mellitus (T2DM) is a chronic non-communicable disease that has reached epidemic proportions and is projected to surpass 850 million by 2050. T2DM is a major risk for cardiovascular disease (CVD), which is the leading cause of death in this population. Traditional stepwise management often leads to therapeutic inertia, where the disease progresses faster than the management. However, emerging evidence shows that early intensive intervention can achieve diabetes remission and significantly reduce CVD risk. This review summarizes data on lifestyle, surgical, and pharmacologic pathways to remission and illustrates that early remission confers a durable “legacy effect,” improving long-term cardiovascular outcomes and survival. View this paper
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Articles (21)

  • Article
  • Open Access
1,848 Views
25 Pages

Prevalence of Alcohol Use Disorder Among Hospital Admissions with Type 2 Diabetes in Spain: Trends from 2016 to 2023 and Predictors of Hospitalization and In-Hospital Mortality

  • Lucia Jiménez-Sierra,
  • Ana López-de-Andres,
  • Valentín Hernández-Barrera,
  • Rodrigo Jiménez-Garcia,
  • David Carabantes-Alarcon,
  • Andrés Bodas-Pinedo,
  • Hikaru Kobayashi-García and
  • José J. Zamorano-León

Background/Objectives: Alcohol consumption is a major public health concern, particularly among individuals with type 2 diabetes (T2D), due to its impact on morbidity and mortality. However, alcohol use disorder (AUD) among hospitalized T2D patients...

  • Review
  • Open Access
1 Citations
3,702 Views
10 Pages

Type 2 diabetes is a chronic non-communicable disease that has reached epidemic levels. While there is ample evidence that type 2 diabetes can, for many, be prevented or at least well managed, this disease progresses in most people with type 2 diabet...

(This article belongs to the Special Issue Early Intervention and Treatment Strategies for Diabetes)
  • Article
  • Open Access
1 Citations
3,664 Views
35 Pages

A Study on Risk Factors Associated with Gestational Diabetes Mellitus

  • Isabel Salas Lorenzo,
  • Jair J. Pineda-Pineda,
  • Ernesto Parra Inza,
  • Saylé Sigarreta Ricardo and
  • Sergio José Torralbas Fitz

Background/Objectives: Gestational Diabetes Mellitus (GDM) is a global health issue with immediate and long-term maternal–fetal complications. Current diagnostic approaches, such as the Oral Glucose Tolerance Test (OGTT), have limitations in ac...

(This article belongs to the Special Issue Advances in Diabetes: Prevalence, Risk Factors, Complications, Costs and Disparities)
  • Article
  • Open Access
3 Citations
3,162 Views
13 Pages

Background/Objectives: Adults with type 1 diabetes (T1D) experience disproportionately high rates of depression, anxiety, and psychological distress, yet integration of behavioral health into diabetes care remains limited. The objective of this study...

  • Review
  • Open Access
8 Citations
12,615 Views
12 Pages

Ocular Effects of GLP-1 Receptor Agonists: A Review of Current Evidence and Safety Concerns

  • Giuseppe Maria Albanese,
  • Giacomo Visioli,
  • Ludovico Alisi,
  • Francesca Giovannetti,
  • Luca Lucchino,
  • Marta Armentano,
  • Fiammetta Catania,
  • Marco Marenco and
  • Magda Gharbiya

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as cornerstone therapies for type 2 diabetes mellitus and obesity, offering significant cardiovascular and renal protection. However, recent evidence has sparked interest and concern r...

  • Article
  • Open Access
2,158 Views
15 Pages

Background/Objectives: Peer support offers a promising approach for improving psychosocial outcomes among adults with type 1 diabetes (T1D). However, research has focused largely on the recipients of peer support rather than the individuals who provi...

(This article belongs to the Special Issue Lifestyle Behavior Intervention for Diabetes Prevention and Management: 2nd Edition)
  • Article
  • Open Access
3 Citations
3,571 Views
12 Pages

Background/Objectives: Accurate blood glucose forecasting is critical for closed-loop insulin delivery systems to support effective disease management in people with type 1 diabetes (T1D). While long short-term memory (LSTM) neural networks have show...

  • Review
  • Open Access
1 Citations
4,725 Views
31 Pages

Factors Influencing the Prescription of First-Line Treatment for Type 2 Diabetes Mellitus: A Systematic Review

  • Helena Silva-Moreira,
  • Fernando Moreira,
  • Ângelo Jesus,
  • Matilde Monteiro-Soares and
  • Paulo Santos

Background/Objectives: Understanding prescribing patterns for type 2 diabetes mellitus, a complex condition affecting over 10% of the global adult population, can optimise prescribing practices, guide policymakers in promoting evidence-based medicine...

(This article belongs to the Special Issue Early Intervention and Treatment Strategies for Diabetes)
  • Article
  • Open Access
1 Citations
1,986 Views
16 Pages

Background/Objectives: Early detection of undiagnosed prediabetes (PD) and type 2 diabetes (T2D) could prevent or delay the onset of diabetes and its complications. The dental setting has been suggested as a location for expanding diabetes screening...

  • Article
  • Open Access
1 Citations
2,350 Views
22 Pages

Background/Objectives: Diabetes mellitus, a prevalent metabolic disorder, causes severe complications and economic burden, requiring effective therapeutic strategies. While triglycerides and low-density lipoproteins (LDLs) have been widely studied in...

  • Review
  • Open Access
5 Citations
2,608 Views
15 Pages

Oxidative stress and chronic low-grade inflammation are recognized key drivers of diabetic complications. Lysosomal dysfunction, cellular senescence, and inter-organ stress signaling further aggravate the Redox–Inflammation–Organ Stress A...

  • Article
  • Open Access
1 Citations
2,361 Views
13 Pages

Development and Content Validation of the Insulin Pump Infusion Sets Satisfaction Scale (IPISS): A Self-Reported Questionnaire for Patients with Type 1 Diabetes and Caregivers

  • Marco Del Monte,
  • Giordano Spacco,
  • Andrea Pintabona,
  • Giulia Siri,
  • Stefano Parodi,
  • Filippo Gambarelli,
  • Elena Poirè,
  • Nicola Minuto and
  • Marta Bassi

Background: Patient satisfaction with diabetes technology is increasingly recognized as a key factor in therapeutic success. Patient-reported outcomes (PROs) are gaining importance in diabetes care and in the evaluation of advanced insulin delivery s...

  • Article
  • Open Access
2,197 Views
14 Pages

Validated Diabetes Risk Scores and Their Associations with Lifestyle and Quality of Life in Spanish Workers

  • María Dolores Marzoa Jansana,
  • Pedro Juan Tárraga López,
  • Juan José Guarro Miquel,
  • Ángel Arturo López-González,
  • Pere Riutord Sbert,
  • Carla Busquets-Cortés and
  • José Ignacio Ramírez-Manent

Background: Type 2 diabetes mellitus (T2DM) is a global health concern driven by aging, lifestyle, and socio-economic disparities. Early detection is key, with tools like FINDRISC, QDScore, and CANRISK providing non-invasive screening. Yet, the combi...

  • Article
  • Open Access
2,782 Views
13 Pages

Impact of Diabetes Mellitus, Its Duration, and Associated Complications on Nutritional Intake in Patients at Risk of Malnutrition: A Focused Nutritional Assessment

  • Paloma Pérez López,
  • Jaime González Gutiérrez,
  • Lucía Estévez Asensio,
  • Olatz Izaola Jauregui,
  • David Primo Martín,
  • Beatriz Ramos Bachiller,
  • Eva López Andrés,
  • Daniel De Luis Román and
  • Juan José López Gómez

Background/Objectives: Diabetes mellitus (DM) is a disorder which affects carbohydrate metabolism and has been associated with other conditions such as disease-related malnutrition (DRM), leading to specific challenges in its management. This study a...

  • Article
  • Open Access
1,050 Views
12 Pages

Evaluation of Cardiovascular Risk Factor Control Among People with Diabetes in the Community Pharmacy Setting—A Descriptive Observational Study

  • Marian Zaki,
  • Claire O’Sullivan,
  • Ellen Barrett,
  • Nasim Mirzai,
  • Hazel Thornton,
  • Yazid N. Al Hamarneh and
  • Margaret Bermingham

Background: In some countries, community pharmacists provide advanced services to people with diabetes that improve glycaemic control and cardiovascular risk. This study aims to describe the cardiovascular risk profile of people with diabetes attendi...

  • Article
  • Open Access
1,765 Views
12 Pages

Association Between Hypoglycaemia at the 24–28th-Week OGTT and Obstetric and Neonatal Outcomes in Women with Gestational Diabetes

  • Maria Luís Mazeda,
  • Bruna Silva,
  • Catarina Cidade-Rodrigues,
  • Filipa Moreira,
  • Vânia Benido-Silva,
  • Vânia Gomes,
  • Catarina Chaves,
  • Catarina A. Pereira,
  • Cláudia Machado and
  • Filipe M. Cunha
  • + 8 authors

Introduction: Women with gestational diabetes mellitus (GDM) can present with hypoglycaemia during the oral glucose tolerance test (OGTT), which has been associated with adverse perinatal outcomes. Objectives: We studied whether the presence of hypog...

  • Article
  • Open Access
1 Citations
2,616 Views
13 Pages

Program Evaluation of Do Well, Be Well with Diabetes: Promoting Healthy Living in Adults with Type 2 Diabetes

  • Sumathi Venkatesh,
  • Katelin M. Alfaro Hudak,
  • Morium B. Bably,
  • Stephanie M. Rogus,
  • Danielle Krueger,
  • Heidi Fowler and
  • Michael Laguros

Background/Objectives: Type 2 diabetes (T2D) is a pressing public health challenge in the United States (U.S.). Community-based diabetes education programs equip individuals with T2D with the knowledge and skills to improve dietary behaviors, build c...

  • Article
  • Open Access
2 Citations
2,707 Views
23 Pages

Dietary Behaviors and Psychosocial Factors of People Managing Diabetes During Fasting: A Qualitative Study from Five US Muslim Communities

  • Asma Mahd Ali,
  • Olayinka O. Shiyanbola,
  • Ejura Salihu,
  • Salma Abdelwahab,
  • James E. Bailey and
  • Betty Chewning

Objectives: This study sought to understand dietary behaviors among US Muslim people with Type 2 diabetes while managing diabetes and fasting during Ramadan, identify key psychosocial factors influencing behaviors, and examine how identified factors...

(This article belongs to the Special Issue Lifestyle Behavior Intervention for Diabetes Prevention and Management: 2nd Edition)
  • Article
  • Open Access
1,847 Views
11 Pages

Increased Insulin Resistance in Roma Pregnancies

  • Christina Pagkaki,
  • Ourania Christou,
  • Dimitra Oikonomopoulou,
  • Zoe Siateli,
  • Sofia Kalantaridou,
  • Emmanouil Zoumakis,
  • Georgios Petrakos and
  • Panagiotis Halvatsiotis

30 September 2025

Background: Reduced tissue sensitivity to insulin, as well as the associated increased risk of gestational diabetes mellitus is genetically controlled and often varies racially and geographically. Roma populations constitute a genetically autonomous...

  • Article
  • Open Access
3,866 Views
11 Pages

A Real-World Study of Electronic Prescriptions and Medication Adherence in Bulgaria

  • Nikol Georgieva,
  • Nikolay Gerasimov,
  • Vasil Madzharov and
  • Guenka Petrova

29 September 2025

Background: The implementation of electronic prescriptions in Bulgaria since 2023 provides new opportunities for real-world data analysis of prescribing practices and medication adherence particularly for chronic diseases such as diabetes. Objective:...

  • Case Report
  • Open Access
1 Citations
9,338 Views
9 Pages

A Case of Paradoxical Appetite Increase During Semaglutide Therapy

  • Edin Karisik,
  • Zorica Stanojevic-Ristic,
  • Slobodan Jankovic,
  • Bojana Bozic Cvijan,
  • Marija Djukanovic,
  • Esin Halo and
  • Mersiha Mulic

25 September 2025

Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, is widely used to reduce appetite and promote weight loss in patients with type 2 diabetes. However, individual variability may lead to paradoxical responses. We describe a 60-year-old...

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Diabetology - ISSN 2673-4540