Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma †
1
Department of Advanced Technology, Ahi Evran University, Kırsehir 40000, Turkey
2
Department of Molecular Biology and Genetics, Ahi Evran University, Kırsehir 40000, Turkey
*
Author to whom correspondence should be addressed.
†
Presented at the 2nd International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8–11 November 2017.
Proceedings 2017, 1(10), 1037; https://doi.org/10.3390/proceedings1101037
Published: 10 November 2017
(This article belongs to the Proceedings of Proceedings of the 2nd International Conference on Natural Products for Cancer Prevention and Therapy)
Abstract
:St. John’s wort (Hypericum perforatum L.) is a medicinal plant used for many diseases. Hypericum perforatum has strong historical background about the therapeutic potential. In the present study, we have investigated the cytotoxic activity of the Hypericum perforatum against cultured cervix adenocarcinoma (HeLa) cell line. Antiproliferative effects of Hypericum perforatum on HeLa cells were evaluated by means of the XTT Cell Proliferation Kit (Biological Industries, Israel) according to manufacturer’s instructions, and then the IC50 value was calculated. IC50 value of Hypericum perforatum was found as 120 μg/mL. Therefore, this plant may be a potential natural antitumor drug for cervix adenocarcinoma.
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MDPI and ACS Style
Kavurmacı, R.; Yalcin, S. Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma. Proceedings 2017, 1, 1037. https://doi.org/10.3390/proceedings1101037
AMA Style
Kavurmacı R, Yalcin S. Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma. Proceedings. 2017; 1(10):1037. https://doi.org/10.3390/proceedings1101037
Chicago/Turabian StyleKavurmacı, Rana, and Serap Yalcin. 2017. "Evaluation of In Vitro Anti-Proliferative Activity of St. John’s Wort (Hypericum perforatum Linn.) Plant Extract on Cervix Adenocarcinoma" Proceedings 1, no. 10: 1037. https://doi.org/10.3390/proceedings1101037
