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Tropical Medicine and Infectious Disease, Volume 9, Issue 3

2024 March - 16 articles

Cover Story: Antimicrobial stewardship (AS) is feasible in very-low-birth-weight (VLBW) preterm infants. AS interventions in neonatal intensive care units (NICUs) can be sustained over time with periodic clinical audits and daily discussions of antimicrobial therapies among staff members. This is a single-centre observational study carried out in Italy. Our safe restriction in antibiotic use was mostly directed at shortening antibiotic regimens in uninfected infants, with a policy of 48 h rule-out sepsis. View this paper
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Articles (16)

  • Article
  • Open Access
5 Citations
4,064 Views
15 Pages

A Contribution towards Sustainable Development in the Amazon Based on a Socioeconomic and Environmental Analysis of Visceral Leishmaniasis in the State of Pará, Brazil

  • Claudia do Socorro Carvalho Miranda,
  • Bruna Costa de Souza,
  • Eric Renato Lima Figueiredo,
  • João Simão de Melo Neto,
  • Hilton Pereira da Silva,
  • Marcos Valerio Santos da Silva,
  • Sérgio Luiz Althoff,
  • Tainara Carvalho Garcia Miranda Filgueiras,
  • Debora do Socorro Carvalho Miranda and
  • Nelson Veiga Gonçalves

Human Visceral Leishmaniasis is an endemic public health problem in the Amazon. This article analyzed the spatial distribution of this disease and its relationship with socioeconomic, environmental and public health policy variables in four mesoregio...

  • Article
  • Open Access
10 Citations
5,684 Views
15 Pages

Characteristics of Pathogenic Escherichia coli Associated with Diarrhea in Children under Five Years in Northwestern Ethiopia

  • Berihun Mossie Mulu,
  • Mequanint Addisu Belete,
  • Tiliksew Bialfew Demlie,
  • Habtamu Tassew and
  • Tesfaye Sisay Tessema

Diarrheagenic Escherichia coli (DEC) are the leading cause of infectious diarrhea and pose a significant global, regional, and national burden of disease. This study aimed to investigate the prevalence of six DEC pathotypes in children with diarrhea...

  • Article
  • Open Access
14 Citations
3,967 Views
12 Pages

Multiple-Drug Resistant Shiga Toxin-Producing E. coli in Raw Milk of Dairy Bovine

  • Safir Ullah,
  • Saeed Ul Hassan Khan,
  • Muhammad Jamil Khan,
  • Baharullah Khattak,
  • Fozia Fozia,
  • Ijaz Ahmad,
  • Mohammad Ahmad Wadaan,
  • Muhammad Farooq Khan,
  • Almohannad Baabbad and
  • Sagar M. Goyal

Introduction: Raw milk may contain pathogenic microorganisms harmful to humans, e.g., multidrug-resistant Escherichia coli non-O157:H7, which can cause severe colitis, hemolytic uremia, and meningitis in children. No studies are available on the prev...

  • Review
  • Open Access
13 Citations
9,994 Views
17 Pages

Stop in Time: How to Reduce Unnecessary Antibiotics in Newborns with Late-Onset Sepsis in Neonatal Intensive Care

  • Domenico Umberto De Rose,
  • Maria Paola Ronchetti,
  • Alessandra Santisi,
  • Paola Bernaschi,
  • Ludovica Martini,
  • Ottavia Porzio,
  • Andrea Dotta and
  • Cinzia Auriti

The fear of missing sepsis episodes in neonates frequently leads to indiscriminate use of antibiotics, and prescription program optimization is suggested for reducing this inappropriate usage. While different authors have studied how to reduce antibi...

  • Article
  • Open Access
2,908 Views
18 Pages

A Longitudinal Study in Tunisia to Assess the Anti-RBD IgG and IgA Responses Induced by Three Different COVID-19 Vaccine Platforms

  • Wafa Ben Hamouda,
  • Mariem Hanachi,
  • Sonia Ben Hamouda,
  • Wafa Kammoun Rebai,
  • Adel Gharbi,
  • Amor Baccouche,
  • Jihene Bettaieb,
  • Oussema Souiai,
  • Mohamed Ridha Barbouche and
  • Chaouki Benabdessalem
  • + 2 authors

Background: Vaccination constitutes the best strategy against COVID-19. In Tunisia, seven vaccines standing for the three main platforms, namely RNA, viral vector, and inactivated vaccines, have been used to vaccinate the population at a large scale....

  • Review
  • Open Access
8 Citations
5,776 Views
15 Pages

The burden of dengue has emerged as a serious public health issue due to its impact on morbidity, mortality, and economic burden. Existing surveillance systems are inadequate to provide the necessary data for the prompt and efficient control of dengu...

  • Article
  • Open Access
7 Citations
2,919 Views
14 Pages

Sustaining the Continued Effectiveness of an Antimicrobial Stewardship Program in Preterm Infants

  • Tommaso Zini,
  • Francesca Miselli,
  • Chiara D’Esposito,
  • Lucia Fidanza,
  • Riccardo Cuoghi Costantini,
  • Lucia Corso,
  • Sofia Mazzotti,
  • Cecilia Rossi,
  • Eugenio Spaggiari and
  • Alberto Berardi
  • + 3 authors

Background: There are wide variations in antibiotic use in neonatal intensive care units (NICUs). Limited data are available on antimicrobial stewardship (AS) programs and long-term maintenance of AS interventions in preterm very-low-birth-weight (VL...

  • Article
  • Open Access
4 Citations
4,259 Views
11 Pages

Single-Dose Rifampicin Leprosy Chemoprophylaxis for Household Contacts in Kiribati: An Audit of a Combined Retrospective and Prospective Approach

  • Patrick O. Campbell,
  • Temea Bauro,
  • Erei Rimon,
  • Eretii Timeon,
  • Caitlin Bland,
  • Nabura Ioteba,
  • Nicholas M. Douglas,
  • Arturo Cunanan and
  • Stephen T. Chambers

Kiribati is a Pacific Island nation with a widely dispersed population and one of the highest rates of leprosy worldwide. Single-dose rifampicin post-exposure prophylaxis (SDR-PEP) of leprosy contacts has reduced new case detection rates in controlle...

  • Article
  • Open Access
4 Citations
2,725 Views
11 Pages

Vaccine Hesitancy, Knowledge, and COVID-19 Vaccination in a Sample of Italian and Albanian Healthcare Students Attending an University in Albania

  • Ersilia Buonomo,
  • Fabian Cenko,
  • Gaia Piunno,
  • Daniele Di Giovanni,
  • Enkeleda Gjini,
  • Bora Kërpi,
  • Mariachiara Carestia,
  • Stefania Moramarco,
  • Cristiana Ferrari and
  • Luca Coppeta

Background: Vaccine hesitancy (VH) has increased over the past decade with large geographical variations between countries, posing a threat to global public health. This phenomenon is growing in the general population as well as among healthcare work...

  • Article
  • Open Access
1 Citations
3,034 Views
15 Pages

Operational Differences between Product Development Partnership, Pharmaceutical Industry, and Investigator Initiated Clinical Trials

  • Eric I Nebie,
  • Peter van Eeuwijk,
  • Hélène N. Sawadogo,
  • Elisabeth Reus,
  • Jürg Utzinger and
  • Christian Burri

Medicine development is a lengthy endeavour. Increasing regulatory stringency and trial complexity might lead to reduced efficiency, dwindled output, and elevated costs. However, alternative models are possible. We compared the operational difference...

  • Article
  • Open Access
2 Citations
2,471 Views
15 Pages

What Does a KAP Survey Reveal about the Awareness Regarding Leishmaniasis among the Community of an Endemic Area in Sri Lanka?

  • Mayumi Manamperi,
  • P. Kandegedara,
  • G. I. C. L. De Zoysa,
  • J. M. A. I. K. Jayamanna,
  • E. G. Perera and
  • N. D. Asha Dilrukshi Wijegunawardana

Leishmaniasis is one of the neglected tropical diseases. Studies show that the poor knowledge about epidemiological aspects of leishmaniasis within communities causes the collapse of existing disease control programs. Therefore, the present study foc...

  • Article
  • Open Access
3 Citations
4,102 Views
13 Pages

The aim of this study was to identify factors associated with non-adherence to tuberculosis (TB) preventive treatment among contacts with latent TB infection for new cases of pulmonary TB cases reported in Catalonia in 2019–2021. All contacts a...

  • Article
  • Open Access
3 Citations
3,641 Views
18 Pages

Integrated Strategies for Aedes aegypti Control Applied to Individual Houses: An Approach to Mitigate Vectorial Arbovirus Transmission

  • Danielle Cristina Tenório Varjal de Melo,
  • Eloína Maria de Mendonça Santos,
  • Morgana Nascimento Xavier,
  • Josimara do Nascimento,
  • Victor Araújo Barbosa,
  • André Luiz de Sá Oliveira,
  • Marcos Vinícius Meiado,
  • Maria Alice Varjal de Melo-Santos,
  • Marcelo Henrique Santos Paiva and
  • Cláudia Maria Fontes de Oliveira
  • + 1 author

Aedes aegypti and Culex quinquefasciatus mosquitoes are vectors of different arboviruses that cause a large burden of disease in humans worldwide. A key step towards reducing the impact of arboviruses on humans can be achieved through integrated mosq...

  • Article
  • Open Access
4 Citations
3,789 Views
12 Pages

Training and Active Case Detection to Prevent Leprosy: Effect on Knowledge, Attitude and Skills of Health Workers on Early Diagnosis of Leprosy in a Leprosy Hotspot District in Ethiopia

  • Ephrem Mamo,
  • Dareskedar Tsehay,
  • Seid Hassen,
  • Solomon Getahun,
  • Addis Mengiste,
  • Beletshachew Tadesse,
  • Tesfaye Tadesse,
  • Mengestu Legesse and
  • Kidist Bobosha

Background: Despite all of the efforts, leprosy continues to affect hundreds of thousands of people every year, including children, showing the ongoing transmission of the disease within the population. The transmission of leprosy can be interrupted...

  • Article
  • Open Access
2 Citations
3,417 Views
11 Pages

Ecology and Infection Status of Sand Flies in Rural and Urban Cutaneous Leishmaniasis Endemic Areas in Northwest Ethiopia

  • Wondmeneh Jemberie,
  • Abebe Animut,
  • Sisay Dugassa,
  • Araya Gebresilassie,
  • Roma Melkamu,
  • Esayas Aklilu,
  • Mulugeta Aemero,
  • Johan van Griensven and
  • Myrthe Pareyn

Cutaneous leishmaniasis (CL) caused by Leishmania aethiopica is transmitted by Phlebotomus longipes in northern Ethiopia. No studies have been conducted to investigate the transmission dynamics of CL, despite its high endemicity in both rural and urb...

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Trop. Med. Infect. Dis. - ISSN 2414-6366