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Biomimetics, Volume 9, Issue 5

2024 May - 52 articles

Cover Story: Neuroblastoma is a pediatric tumor that accounts for 15% of childhood cancer deaths. Research has demonstrated that all-trans-retinoic acid (ATRA) inhibits cell growth and promotes differentiation. The substantial chemical and photo instability of ATRA is a significant aspect of its therapeutic value. One known method of shielding retinoids against destabilizing events is to encapsulate them in nanocarriers, such as liposomes. In this study, free ATRA and anionic-liposome-encapsulated ATRA were compared for their effects on human neuroblastoma cell growth and differentiation. The new anionic liposomal formulation improved ATRA’s differentiation efficiency, as evidenced by an increase in neurite-bearing cells. This work, which creates and tests a novel nanocarrier, is an example of the first stage in developing new therapeutic settings. View this paper
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Articles (52)

  • Review
  • Open Access
10 Citations
4,698 Views
30 Pages

Advancement in Cancer Vasculogenesis Modeling through 3D Bioprinting Technology

  • Arvind Kumar Shukla,
  • Sik Yoon,
  • Sae-Ock Oh,
  • Dongjun Lee,
  • Minjun Ahn and
  • Byoung Soo Kim

Cancer vasculogenesis is a pivotal focus of cancer research and treatment given its critical role in tumor development, metastasis, and the formation of vasculogenic microenvironments. Traditional approaches to investigating cancer vasculogenesis fac...

  • Case Report
  • Open Access
1 Citations
2,133 Views
9 Pages

An efficient treatment plan using a temporary anchorage device should be built following the principle of reducing the number of tads to obtain a multiple biomechanical advantage. The following case report concerns the Biga system, a strategy that su...

  • Article
  • Open Access
3 Citations
2,368 Views
20 Pages

The prediction of patient survival is crucial for guiding the treatment process in healthcare. Healthcare professionals rely on analyzing patients’ clinical characteristics and findings to determine treatment plans, making accurate predictions...

  • Article
  • Open Access
5 Citations
3,028 Views
29 Pages

Development of a New Aggregation Method to Remove Nanoplastics from the Ocean: Proof of Concept Using Mussel Exposure Tests

  • Antonio Cid-Samamed,
  • Catarina S. E. Nunes,
  • Cristina Lomas Martínez and
  • Mário S. Diniz

The overproduction and mismanagement of plastics has led to the accumulation of these materials in the environment, particularly in the marine ecosystem. Once in the environment, plastics break down and can acquire microscopic or even nanoscopic size...

  • Feature Paper
  • Article
  • Open Access
11 Citations
2,727 Views
22 Pages

As IoT metering devices become increasingly prevalent, the smart energy grid encounters challenges associated with the transmission of large volumes of data affecting the latency of control services and the secure delivery of energy. Offloading compu...

  • Article
  • Open Access
4 Citations
2,271 Views
16 Pages

The pectoral fin propulsion of a bionic robotic fish always consists of two phases: propulsion and recovery. The robotic fish moves in a burst-and-coast swimming manner. This study aims to analyze a pair of bionic robotic fish with rigid pectoral fin...

  • Case Report
  • Open Access
3 Citations
3,499 Views
7 Pages

Anterior Esthetic Restorations with the Stratified Stamp Technique: A Case Report

  • Camillo D’Arcangelo,
  • Matteo Buonvivere and
  • Francesco De Angelis

Anterior teeth restoration represents a challenge for dentists, who often rely on the dental technician’s wax-up. The proposed Stratified Stamp Technique (SST) allows for clinically reproducing the wax-up in a quick and easy way. A patient with...

  • Article
  • Open Access
1 Citations
2,423 Views
16 Pages

Modeling the Electrical Activity of the Heart via Transfer Functions and Genetic Algorithms

  • Omar Rodríguez-Abreo,
  • Mayra Cruz-Fernandez,
  • Carlos Fuentes-Silva,
  • Mario A. Quiroz-Juárez and
  • José L. Aragón

Although healthcare and medical technology have advanced significantly over the past few decades, heart disease continues to be a major cause of mortality globally. Electrocardiography (ECG) is one of the most widely used tools for the detection of h...

  • Article
  • Open Access
23 Citations
2,728 Views
28 Pages

In recent years, swarm intelligence optimization methods have been increasingly applied in many fields such as mechanical design, microgrid scheduling, drone technology, neural network training, and multi-objective optimization. In this paper, a mult...

  • Review
  • Open Access
30 Citations
8,137 Views
58 Pages

Insects, renowned for their abundant and renewable biomass, stand at the forefront of biomimicry-inspired research and offer promising alternatives for chitin and chitosan production considering mounting environmental concerns and the inherent limita...

  • Article
  • Open Access
8 Citations
2,044 Views
16 Pages

A Biologically Inspired Movement Recognition System with Spiking Neural Networks for Ambient Assisted Living Applications

  • Athanasios Passias,
  • Karolos-Alexandros Tsakalos,
  • Ioannis Kansizoglou,
  • Archontissa Maria Kanavaki,
  • Athanasios Gkrekidis,
  • Dimitrios Menychtas,
  • Nikolaos Aggelousis,
  • Maria Michalopoulou,
  • Antonios Gasteratos and
  • Georgios Ch. Sirakoulis

This study presents a novel solution for ambient assisted living (AAL) applications that utilizes spiking neural networks (SNNs) and reconfigurable neuromorphic processors. As demographic shifts result in an increased need for eldercare, due to a lar...

  • Review
  • Open Access
12 Citations
4,714 Views
11 Pages

In order to reduce the toxicological impact on healthy cells and to improve the therapeutic response, many drug delivery systems have been fabricated and analysed, involving the use of different natural and synthetic materials at macro-, micro- and n...

  • Review
  • Open Access
4 Citations
2,960 Views
12 Pages

Clinical Application of Unidirectional Porous Hydroxyapatite to Bone Tumor Surgery and Other Orthopedic Surgery

  • Toshiyuki Kunisada,
  • Eiji Nakata,
  • Tomohiro Fujiwara,
  • Toshiaki Hata,
  • Kohei Sato,
  • Haruyoshi Katayama,
  • Ayana Kondo and
  • Toshifumi Ozaki

Unidirectional porous hydroxyapatite (UDPHAp) was developed as a remarkable scaffold characterized by a distinct structure with unidirectional pores oriented in the horizontal direction and connected through interposes. We evaluated the radiographic...

  • Article
  • Open Access
6 Citations
2,852 Views
22 Pages

According to the Magnus principle, a rotating cylinder experiences a lateral force perpendicular to the incoming flow direction. This phenomenon can be harnessed to boost the lift of an airfoil by positioning a rotating cylinder at the leading edge....

  • Article
  • Open Access
5 Citations
3,104 Views
28 Pages

Intelligent Learning-Based Methods for Determining the Ideal Team Size in Agile Practices

  • Rodrigo Olivares,
  • Rene Noel,
  • Sebastián M. Guzmán,
  • Diego Miranda and
  • Roberto Munoz

One of the significant challenges in scaling agile software development is organizing software development teams to ensure effective communication among members while equipping them with the capabilities to deliver business value independently. A for...

  • Article
  • Open Access
43 Citations
5,435 Views
30 Pages

Multi-Strategy Improved Dung Beetle Optimization Algorithm and Its Applications

  • Mingjun Ye ,
  • Heng Zhou,
  • Haoyu Yang,
  • Bin Hu and
  • Xiong Wang

The dung beetle optimization (DBO) algorithm, a swarm intelligence-based metaheuristic, is renowned for its robust optimization capability and fast convergence speed. However, it also suffers from low population diversity, susceptibility to local opt...

  • Article
  • Open Access
3 Citations
4,000 Views
21 Pages

This paper explores if plants are capable of responding to human movement by changes in their electrical signals. Toward that goal, we conducted a series of experiments, where humans over a period of 6 months were performing different types of euryth...

  • Article
  • Open Access
6 Citations
5,067 Views
14 Pages

Placental trophoblast invasion is critical for establishing the maternal–fetal interface, yet the mechanisms driving trophoblast-induced maternal arterial remodeling remain elusive. To address this gap, we developed a three-dimensional microflu...

  • Article
  • Open Access
3,011 Views
21 Pages

Due to their advantages of good stability, adaptability, and flexibility, multi-legged robots are increasingly important in fields such as rescue, military, and healthcare. This study focuses on the millipede, a multi-segmented organism, and designs...

  • Article
  • Open Access
2,286 Views
16 Pages

In this paper, we describe a sheet-shaped throwable transforming robot. Sheet-type robots can change their shape to perform tasks according to the situation. Therefore, they are expected to be useful in places with many restrictions, such as disaster...

  • Review
  • Open Access
5 Citations
3,776 Views
12 Pages

Redefining Surgical Materials: Applications of Silk Fibroin in Osteofixation and Fracture Repair

  • Jose A. Foppiani,
  • Iulianna C. Taritsa,
  • Lacey Foster,
  • Armaan Patel,
  • Angelica Hernandez Alvarez,
  • Daniela Lee,
  • Gavin J. Lin,
  • Theodore C. Lee,
  • Dominika Gavlasova and
  • Samuel J. Lin
  • + 2 authors

Silk and silk derivatives have emerged as a possible alternative in surgical device development, offering mechanical strength, biocompatibility, and environmental sustainability. Through a systematic review following PRISMA guidelines, this study eva...

  • Review
  • Open Access
14 Citations
3,819 Views
17 Pages

Crystal-Inspired Cellular Metamaterials and Triply Periodic Minimal Surfaces

  • Maxim Arsentev,
  • Eduard Topalov,
  • Sergey Balabanov,
  • Evgenii Sysoev,
  • Igor Shulga,
  • Marsel Akhmatnabiev,
  • Maxim Sychov,
  • Ekaterina Skorb and
  • Michael Nosonovsky

Triply periodic minimal surfaces (TPMSs) are found in many natural objects including butterfly wings, sea urchins, and biological membranes. They simultaneously have zero mean curvature at every point and a crystallographic group symmetry. A metamate...

  • Article
  • Open Access
4 Citations
2,079 Views
18 Pages

Combination of a Synthetic Bioceramic Associated with a Polydioxanone-Based Membrane as an Alternative to Autogenous Bone Grafting

  • Paula Buzo Frigério,
  • Juliana de Moura,
  • Letícia Pitol-Palin,
  • Naara Gabriela Monteiro,
  • Carlos Fernando Mourão,
  • Jamil Awad Shibli and
  • Roberta Okamoto

The purpose of this study was to evaluate the repair process in rat calvaria filled with synthetic biphasic bioceramics (Plenum® Osshp-70:30, HA:βTCP) or autogenous bone, covered with a polydioxanone membrane (PDO). A total of 48 rats were d...

  • Article
  • Open Access
7 Citations
2,860 Views
33 Pages

A Novel Approach to Combinatorial Problems: Binary Growth Optimizer Algorithm

  • Dante Leiva,
  • Benjamín Ramos-Tapia,
  • Broderick Crawford,
  • Ricardo Soto and
  • Felipe Cisternas-Caneo

The set-covering problem aims to find the smallest possible set of subsets that cover all the elements of a larger set. The difficulty of solving the set-covering problem increases as the number of elements and sets grows, making it a complex problem...

  • Article
  • Open Access
2 Citations
2,881 Views
12 Pages

Clap-and-Fling Mechanism of Climbing-Flight Coccinella Septempunctata

  • Lili Yang,
  • Huichao Deng,
  • Kai Hu and
  • Xilun Ding

Previous studies on the clap–fling mechanism have predominantly focused on the initial downward and forward phases of flight in miniature insects, either during hovering or forward flight. However, this study presents the first comprehensive ki...

  • Article
  • Open Access
5 Citations
2,392 Views
14 Pages

A Microactuator Array Based on Ionic Electroactive Artificial Muscles for Cell Mechanical Stimulation

  • Jing Gu,
  • Zixing Zhou,
  • Yang Xie,
  • Xiaobin Zhu,
  • Guoyou Huang and
  • Zuoqi Zhang

Mechanical stimulation is prevalent within organisms, and appropriate regulation of such stimulation can significantly enhance cellular functions. Consequently, the in vitro construction and simulation of mechanical stimulation have emerged as a rese...

  • Article
  • Open Access
14 Citations
2,523 Views
39 Pages

The sand cat swarm optimization algorithm (SCSO) is a novel metaheuristic algorithm that has been proposed in recent years. The algorithm optimizes the search ability of individuals by mimicking the hunting behavior of sand cat groups in nature, ther...

  • Review
  • Open Access
24 Citations
11,126 Views
35 Pages

Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin

  • Sol Youn,
  • Mi-Ran Ki,
  • Mohamed A. A. Abdelhamid and
  • Seung-Pil Pack

Biomimetic materials have become a promising alternative in the field of tissue engineering and regenerative medicine to address critical challenges in wound healing and skin regeneration. Skin-mimetic materials have enormous potential to improve wou...

  • Article
  • Open Access
8 Citations
2,320 Views
18 Pages

This paper presents an improved pelican optimization algorithm (IPOA) to solve the economic load dispatch problem. The vertical crossover operator in the crisscross optimization algorithm is integrated to expand the diversity of the population in the...

  • Review
  • Open Access
6 Citations
3,739 Views
26 Pages

Chronic wounds such as diabetic ulcers are a major complication in diabetes caused by hyperglycemia, prolonged inflammation, high oxidative stress, and bacterial bioburden. Bioactive biopolymers have been found to have a biological response in wound...

  • Article
  • Open Access
4 Citations
3,690 Views
15 Pages

Radiographic Study of Transcrestal Sinus Floor Elevation Using Osseodensification Technique with Graft Material: A Pilot Study

  • Khrystyna Sulyhan-Sulyhan,
  • Javier Barberá-Millán,
  • Carolina Larrazábal-Morón,
  • Julián Espinosa-Giménez and
  • María Dolores Gómez-Adrián

This pilot study aimed to evaluate the level of implant success after transcrestal sinus floor elevation (tSFE) using the osseodensification technique (OD) combined with beta-tricalcium phosphate (β-TCP) by analyzing clinical and radiographic re...

  • Article
  • Open Access
2 Citations
2,859 Views
17 Pages

High vertical jumping motion, which enables a humanoid robot to leap over obstacles, is a direct reflection of its extreme motion capabilities. This article proposes a single sequential kino-dynamic trajectory optimization method to solve the whole-b...

  • Review
  • Open Access
16 Citations
10,669 Views
18 Pages

Recent advancements in biomimetics have spurred significant innovations in prosthetic limb development by leveraging the intricate designs and mechanisms found in nature. Biomimetics, also known as “nature-inspired engineering”, involves...

  • Article
  • Open Access
1 Citations
1,749 Views
41 Pages

To inhibit the deep conversion of partial oxidation products (POX-products) in C-H bonds’ functionalization utilizing O2, 5-(4-(chloromethyl)phenyl)-10,15,20-tris(perfluorophenyl)porphyrin cobalt(II) and 5-(4-(chloromethyl)phenyl)-10,15,20-tris...

  • Article
  • Open Access
20 Citations
3,737 Views
30 Pages

A Sinh–Cosh-Enhanced DBO Algorithm Applied to Global Optimization Problems

  • Xiong Wang,
  • Yaxin Wei,
  • Zihao Guo,
  • Jihong Wang,
  • Hui Yu and
  • Bin Hu

The Dung beetle optimization (DBO) algorithm, devised by Jiankai Xue in 2022, is known for its strong optimization capabilities and fast convergence. However, it does have certain limitations, including insufficiently random population initialization...

  • Article
  • Open Access
24 Citations
3,649 Views
27 Pages

The traditional golden jackal optimization algorithm (GJO) has slow convergence speed, insufficient accuracy, and weakened optimization ability in the process of finding the optimal solution. At the same time, it is easy to fall into local extremes a...

  • Article
  • Open Access
2 Citations
2,630 Views
16 Pages

Preclinical testing of medical devices is an essential step in the product life cycle, whereas testing of cardiovascular implants requires specialised testbeds or numerical simulations using computer software Ansys 2016. Existing test setups used to...

  • Article
  • Open Access
1 Citations
2,337 Views
20 Pages

Poly lactic acid (PLA) is one of the most commonly used bio-derived thermoplastic polymers in 3D and 4D printing applications. The determination of PLA surface properties is of capital importance in 3D/4D printing technology. The surface thermodynami...

  • Systematic Review
  • Open Access
7 Citations
6,128 Views
17 Pages

Influence of Immediate Dentin Sealing on Bond Strength of Resin-Based CAD/CAM Restoratives to Dentin: A Systematic Review of In Vitro Studies

  • Iliana Antoniou,
  • Petros Mourouzis,
  • Dimitrios Dionysopoulos,
  • Panagiotis Pandoleon and
  • Kosmas Tolidis

Immediate dentin sealing (IDS) is a method of improving the bond strength of indirect dental restorative materials to dentin and belongs to the biomimetic protocols of contemporary dentistry. The purpose of this systematic review was to evaluate the...

  • Article
  • Open Access
1,874 Views
16 Pages

Objective: The prediction of upcoming circular walking during linear walking is important for the usability and safety of the interaction between a lower limb assistive device and the wearer. This study aims to build a bilateral elimination rule-base...

  • Article
  • Open Access
12 Citations
4,170 Views
16 Pages

Seahorse-Tail-Inspired Soft Pneumatic Actuator: Development and Experimental Characterization

  • Michele Gabrio Antonelli,
  • Pierluigi Beomonte Zobel,
  • Muhammad Aziz Sarwar and
  • Nicola Stampone

The study of bio-inspired structures and their reproduction has always fascinated humans. The advent of soft robotics, thanks to soft materials, has enabled considerable progress in this field. Over the years, polyps, worms, cockroaches, jellyfish, a...

  • Article
  • Open Access
2 Citations
2,415 Views
16 Pages

Biped Gait Stability Classification Based on the Predicted Step Viability

  • Pedro Parik-Americano,
  • Jorge Igual,
  • Larissa Driemeier,
  • Eric Cito Becman and
  • Arturo Forner-Cordero

In this paper, we address the challenge of ensuring stability in bipedal walking robots and exoskeletons. We explore the feasibility of real-time implementation for the Predicted Step Viability algorithm (PSV), a complex multi-step optimization crite...

  • Article
  • Open Access
5 Citations
2,539 Views
19 Pages

An incremental deep deterministic policy gradient (IDDPG) algorithm is devised for the trajectory tracking control of a four-wing variable sweep (FWVS) aircraft with uncertainty. The IDDPG algorithm employs the line-of-sight (LOS) method for path tra...

  • Article
  • Open Access
4 Citations
2,487 Views
19 Pages

Reducing Inert Materials for Optimal Cell–Cell and Cell–Matrix Interactions within Microphysiological Systems

  • Claudia Olaizola-Rodrigo,
  • Héctor Castro-Abril,
  • Ismael Perisé-Badía,
  • Lara Pancorbo,
  • Ignacio Ochoa,
  • Rosa Monge and
  • Sara Oliván

In the pursuit of achieving a more realistic in vitro simulation of human biological tissues, microfluidics has emerged as a promising technology. Organ-on-a-chip (OoC) devices, a product of this technology, contain miniature tissues within microflui...

  • Article
  • Open Access
2 Citations
2,469 Views
20 Pages

In addition to water repellency, superhydrophobic leaves of plants such as Salvinia molesta adsorb oil and separate it from water surfaces. This phenomenon has been the inspiration for a new method of oil–water separation, the bionic oil adsorb...

  • Article
  • Open Access
2 Citations
3,481 Views
16 Pages

Design of Bionic Foot Inspired by the Anti-Slip Cushioning Mechanism of Yak Feet

  • Weijun Tian,
  • Kuiyue Zhou,
  • Zhu Chen,
  • Ziteng Shen,
  • Zhirui Wang,
  • Lei Jiang and
  • Qian Cong

In recent years, legged robots have been more and more widely used on non-structured terrain, and their foot structure has an important impact on the robot’s motion performance and stability. The structural characteristics of the yak foot sole...

  • Article
  • Open Access
3 Citations
3,281 Views
27 Pages

Dynamic 3D Point-Cloud-Driven Autonomous Hierarchical Path Planning for Quadruped Robots

  • Qi Zhang,
  • Ruiya Li,
  • Jubiao Sun,
  • Li Wei,
  • Jun Huang and
  • Yuegang Tan

Aiming at effectively generating safe and reliable motion paths for quadruped robots, a hierarchical path planning approach driven by dynamic 3D point clouds is proposed in this article. The developed path planning model is essentially constituted of...

  • Review
  • Open Access
2 Citations
4,118 Views
14 Pages

Analysis of the Prognostic Factors That Influence the Outcome of Periapical Surgery, including Biomimetic Membranes for Tissue Regeneration: A Review

  • Antonio J. Saiz-Pardo-Pinos,
  • Francisco J. Manzano-Moreno,
  • Esther Muñoz-Soto,
  • María Paloma González-Rodríguez,
  • Nuria Romero-Olid and
  • María Victoria Olmedo-Gaya

The objective of this study was to analyze the prognostic factors that influence the outcome of periapical surgery. A systematic search of the literature was carried out using PubMed and Scopus databases between January 2000 and December 2023 with no...

  • Article
  • Open Access
3 Citations
2,840 Views
13 Pages

Effects of Anionic Liposome Delivery of All–Trans–Retinoic Acid on Neuroblastoma Cell Differentiation

  • Antonio Minò,
  • Francesco Lopez,
  • Roberto Barbaro,
  • Maria Barile,
  • Luigi Ambrosone and
  • Matilde Colella

All–trans–retinoic acid (ATRA) has long been known to affect cell growth and differentiation. To improve ATRA’s therapeutic efficacy and pharmacodynamics, several delivery systems have been used. In this study, free ATRA and anionic...

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Biomimetics - ISSN 2313-7673