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Journal of Fungi, Volume 8, Issue 4

April 2022 - 93 articles

Cover Story: Mucormycosis is a life-threatening disease caused by Mucoromycota species such as Rhizopus delemar. Mucormycosis is most effectively treated with amphotericin B (AmB) and particularly with AmB-loaded liposomes (AmB-LLs). However, even after treatment, there is still a 50% mortality rate. We used the pathogen receptor Dectin-1 to target AmB-LLs to R. delemar. DEC1-AmB-LLs bound with great efficiency to exopolysaccharide matrices associated with sporangiospores, germlings, and mature hyphae. DEC1-AmB-LLs delivering sub-micromolar concentrations of AmB were an order of magnitude more efficient at inhibiting or killing R. delemar than AmB-LLs. The cover image shows rhodamine B-tagged DEC1-AmB-LLs (red) that are bound to calcofluor white-stained R. delemar germlings (green). View this paper
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Articles (93)

  • Review
  • Open Access
14 Citations
5,366 Views
17 Pages

Invasive Respiratory Fungal Infections in COVID-19 Critically Ill Patients

  • Francesca Raffaelli,
  • Eloisa Sofia Tanzarella,
  • Gennaro De Pascale and
  • Mario Tumbarello

17 April 2022

Patients with coronavirus disease 19 (COVID-19) admitted to the intensive care unit (ICU) often develop respiratory fungal infections. The most frequent diseases are the COVID-19 associated pulmonary aspergillosis (CAPA), COVID-19 associated pulmonar...

  • Article
  • Open Access
6 Citations
4,828 Views
10 Pages

Estimated Incidence and Prevalence of Serious Fungal Infections in Morocco

  • Badre Eddine Lmimouni,
  • Christophe Hennequin,
  • Richard O. S. Penney and
  • David W. Denning

17 April 2022

Few data are published from Morocco on fungal disease, although numerous case reports attest to a wide range of conditions in the country. Here, we estimate for the first time the incidence and prevalence of serious fungal diseases in the country. De...

  • Review
  • Open Access
14 Citations
6,355 Views
16 Pages

Current Landscape of Coccidioidomycosis

  • Ryan Boro,
  • Prema C. Iyer and
  • Maciej A. Walczak

17 April 2022

Coccidioidomycosis, also known as Valley fever, is an endemic fungal infection commonly found in the southwestern parts of the United States. However, the disease has seen an increase in both in its area of residency and its prevalence. This review c...

  • Article
  • Open Access
46 Citations
6,859 Views
15 Pages

16 April 2022

Nanoparticles (NPs) have attracted great interest in various fields owing to their antimicrobial activity; however, the use of NPs as fungicides on plants has not been sufficiently investigated. In this study, the antifungal activities of sulfur nano...

  • Article
  • Open Access
10 Citations
5,131 Views
14 Pages

Unravelling the Molecular Identification and Antifungal Susceptibility Profiles of Aspergillus spp. Isolated from Chronic Pulmonary Aspergillosis Patients in Jakarta, Indonesia: The Emergence of Cryptic Species

  • Anna Rozaliyani,
  • Asriyani Abdullah,
  • Findra Setianingrum,
  • Wellyzar Sjamsuridzal,
  • Retno Wahyuningsih,
  • Anom Bowolaksono,
  • Ayu Eka Fatril,
  • Robiatul Adawiyah,
  • Mulyati Tugiran and
  • Ridhawati Syam
  • + 3 authors

16 April 2022

Cryptic species of Aspergillus have rapidly increased in the last few decades. Chronic pulmonary aspergillosis (CPA) is a debilitating fungal infection frequently affecting patients with previous TB. The identification and antifungal susceptibility p...

  • Article
  • Open Access
10 Citations
3,743 Views
17 Pages

Culturable Yeast Diversity of Grape Berries from Vitis vinifera ssp. sylvestris (Gmelin) Hegi

  • Gustavo Cordero-Bueso,
  • Ileana Vigentini,
  • Roberto Foschino,
  • David Maghradze,
  • Marina Ruiz-Muñoz,
  • Francisco Benitez-Trujillo and
  • Jesús M. Cantoral

16 April 2022

Vitis vinifera L. ssp. sylvestris (Gmelin) Hegi is recognized as the dioecious parental generation of today’s cultivars. Climatic change and the arrival of pathogens and pests in Europe led it to be included on the International Union for Conse...

  • Article
  • Open Access
32 Citations
6,403 Views
22 Pages

16 April 2022

Botryosphaeria dieback (BD) is a grapevine trunk disease (GTD) causing significant yield losses and limiting the lifespan of vineyards worldwide. Fungi responsible for BD infect grapevines primarily through pruning wounds, and thus pruning wound prot...

  • Article
  • Open Access
9 Citations
3,495 Views
14 Pages

Revisit of the Association between Cytomegalovirus Infection and Invasive Fungal Infection after Allogeneic Hematopoietic Stem Cell Transplantation: A Real-World Analysis from a High CMV Seroprevalence Area

  • Tsung-Jang Yeh,
  • Ching-I Yang,
  • Chien-Tzu Huang,
  • Min-Hung Wang,
  • Tzer-Ming Chuang,
  • Ya-Lun Ke,
  • Yuh-Ching Gau,
  • Jeng-Shiun Du,
  • Hui-Ching Wang and
  • Shih-Feng Cho
  • + 4 authors

16 April 2022

Infection is a major complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT) especially cytomegalovirus (CMV) infection and invasive fungal infection (IFI). Taiwan is a high CMV seroprevalence area. Our study aimed to evalua...

  • Article
  • Open Access
7 Citations
4,081 Views
13 Pages

16 April 2022

Monacolin J (MJ), a key precursor of Lovastatin, could synthesize important statin drug simvastatin by hydrolyzing lovastatin and adding different side chains. In this study, to reduce the cumbersome hydrolysis of lovastatin to produce MJ in the nati...

  • Review
  • Open Access
42 Citations
5,760 Views
14 Pages

Regulatory Mechanism of Trap Formation in the Nematode-Trapping Fungi

  • Mei-Chen Zhu,
  • Xue-Mei Li,
  • Na Zhao,
  • Le Yang,
  • Ke-Qin Zhang and
  • Jin-Kui Yang

16 April 2022

Nematode-trapping (NT) fungi play a significant role in the biological control of plant- parasitic nematodes. NT fungi, as a predator, can differentiate into specialized structures called “traps” to capture, kill, and consume nematodes at...

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J. Fungi - ISSN 2309-608X