March 2023 - 117 articles
Nuclei segmentation and classification are two basic and essential tasks in computer-aided diagnosis of digital pathology images, and those deep-learning-based methods have achieved significant success. Unfortunately, most of the existing studies acc...
Pentalenene is a ternary cyclic sesquiterpene formed via the ionization and cyclization of farnesyl pyrophosphate (FPP), which is catalyzed by pentalenene synthase (PentS). To better understand the cyclization reactions, it is necessary to identify m...
The recent COVID-19 pandemic has highlighted the inadequacies of existing diagnostic techniques and the need for rapid and accurate diagnostic systems. Although molecular tests such as RT-PCR are the gold standard, they cannot be employed as point-of...
Heat shock proteins (HSPs) play critical roles in regulating different mechanisms under high-temperature conditions. HSPs have been identified and well-studied in different plants. However, there is a lack of information about their genomic organizat...
Antibodies are key proteins of the immune system, and they are widely used for both research and theragnostic applications. Among them, camelid immunoglobulins (IgG) differ from the canonical human IgG molecules, as their light chains are completely...
Ultrasound imaging is cost effective, radiation-free, portable, and implemented routinely in clinical procedures. Nonetheless, image quality is characterized by a granulated appearance, a poor SNR, and speckle noise. Specific for breast tumors, the m...
Long cytoplasmic processes of osteocytes orchestrate bone activity by integration of biochemical and mechanical signals and regulate load-induced bone adaptation. Low-Intensity Pulsed Ultrasound (LIPUS) is a clinically used technique for fracture hea...
Viscoelastic point-of-care haemostatic resuscitation methods, such as ROTEM or TEG, are crucial in deciding on time-efficient personalised coagulation interventions. International transfusion guidelines emphasise increased patient safety and reduced...
In this study, we propose a set of nonlinear differential equations to model the dynamic growth of avascular stage tumors, considering nutrient supply from underlying tissue, innate immune response, contact inhibition of cell migration, and interacti...
The effect of extracellular matrix (ECM) stiffness on embryonic trophoblast cells invasion during mammalian embryo implantation remains largely unknown. In this study, we investigated the effects of ECM stiffness on various aspects of human trophobla...
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