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Toxics, Volume 10, Issue 2

February 2022 - 58 articles

Cover Story: The occurrence of transformation products (TPs) of emerging pollutants has been of potential concern in aquatic environments. Nonetheless, it is unclear how TPs are formed and affect organisms in aquatic ecosystem. Thanking to recent advances in analytics and biotechnology, identification of TPs and their formation mechanisms can be explored by non-target screening (NTS) using high-resolution mass spectrometry (HRMS) and in vivo/vitro bioassay using model organisms. In this review, recent progress in TP research including their exposure and effect assessments is summarized. In particular, the review covers prospective research efforts on TP, such as identification of the products using NTS, and assessment of potential risk. View this paper
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Articles (58)

  • Article
  • Open Access
8 Citations
4,266 Views
13 Pages

21 February 2022

Earthworms are well-established model organisms for testing the effects of heavy metal pollution. How DNA methylation affects cadmium (Cd) detoxification processes such as the expression of metallothionein 2 (MT2), however, is largely unknown. We the...

  • Feature Paper
  • Article
  • Open Access
15 Citations
4,749 Views
20 Pages

Nonylphenol Polyethoxylates Enhance Adipose Deposition in Developmentally Exposed Zebrafish

  • Christopher D. Kassotis,
  • Matthew K. LeFauve,
  • Yu-Ting Tiffany Chiang,
  • Megan M. Knuth,
  • Stacy Schkoda and
  • Seth W. Kullman

20 February 2022

Alkylphenol polyethoxylates (APEOs), such as nonylphenol ethoxylates (NPEOs), are high-production-volume surfactants used in laundry detergents, hard-surface cleaners, pesticide formulations, textile production, oils, paints, and other products. NPEO...

  • Feature Paper
  • Article
  • Open Access
50 Citations
5,971 Views
13 Pages

Removal of Hexavalent Chromium(VI) from Wastewater Using Chitosan-Coated Iron Oxide Nanocomposite Membranes

  • Jung Eun Park,
  • Jun-Ho Shin,
  • Wonzin Oh,
  • Sang-June Choi,
  • Jeongju Kim,
  • Chorong Kim and
  • Jongho Jeon

19 February 2022

Chromium is a toxic and carcinogenic heavy metal that originates from various human activities. Therefore, the effective removal of chromium from aqueous solutions is an extremely important global challenge. Herein, we report a chitosan-coated iron o...

  • Article
  • Open Access
12 Citations
3,199 Views
15 Pages

PBDEs Found in House Dust Impact Human Lung Epithelial Cell Homeostasis

  • Antonio Zandona,
  • Karla Jagić,
  • Marija Dvoršćak,
  • Josip Madunić,
  • Darija Klinčić and
  • Maja Katalinić

19 February 2022

The toxicity of eight polybrominated diphenyl ethers (PBDEs) congeners detected in environmental and biological samples (BDE-28, -47, -99, -100, -153, -154, -183, and -209) was evaluated on the epithelial lung cells. Exposure to these PBDEs increased...

  • Article
  • Open Access
12 Citations
5,791 Views
14 Pages

Using Human Biomonitoring Data to Support Risk Assessment of Cosmetic Ingredients—A Case Study of Benzophenone-3

  • Christophe Rousselle,
  • Matthieu Meslin,
  • Tamar Berman,
  • Marjolijn Woutersen,
  • Wieneke Bil,
  • Jenna Wildeman and
  • Qasim Chaudhry

19 February 2022

Safety assessment of UV filters for human health by the Scientific Committee on Consumer Safety (SCCS) is based on the estimation of internal dose following external (skin) application of cosmetic products, and comparison with a toxicological referen...

  • Article
  • Open Access
28 Citations
5,034 Views
44 Pages

Neuro-Particle Swarm Optimization Based In-Situ Prediction Model for Heavy Metals Concentration in Groundwater and Surface Water

  • Kevin Lawrence M. De Jesus,
  • Delia B. Senoro,
  • Jennifer C. Dela Cruz and
  • Eduardo B. Chan

18 February 2022

Limited monitoring activities to assess data on heavy metal (HM) concentration contribute to worldwide concern for the environmental quality and the degree of toxicants in areas where there are elevated metals concentrations. Hence, this study used i...

  • Article
  • Open Access
7 Citations
4,404 Views
9 Pages

Chromosome Damage in Relation to Recent Radiation Exposure and Radiation Quality in Nuclear Power Plant Workers

  • Yang Jee Kim,
  • Joong Won Lee,
  • Yoon Hee Cho,
  • Young Joo Choi,
  • Younghyun Lee and
  • Hai Won Chung

18 February 2022

Ionizing radiation is a well-known carcinogen that causes genomic instability. However, the biological and carcinogenetic effects of occupational radiation exposure at low doses have not been extensively studied. The aim of this study was to assess c...

  • Feature Paper
  • Article
  • Open Access
8 Citations
2,685 Views
14 Pages

18 February 2022

We previously demonstrated that polybrominated diphenyl ethers (PBDEs) inhibit the growth of axons in primary rat hippocampal neurons. Here, we test the hypothesis that PBDE effects on axonal morphogenesis are mediated by thyroid hormone and/or react...

  • Article
  • Open Access
18 Citations
3,527 Views
14 Pages

Pollution Characteristics and Risk Prediction of Endocrine Disruptors in Lakes of Wuhan

  • Yurui Zhang,
  • Jun Cao,
  • Tan Ke,
  • Yue Tao,
  • Wanyin Wu,
  • Panpan Wang,
  • Min Zhou and
  • Lanzhou Chen

18 February 2022

As a new and ubiquitous trace organic pollutant, endocrine-disrupting compounds (EDCs) can cause endocrine-disrupting effects on organisms even at low levels. However, little information is available on the resource and assessment of EDC risks in the...

  • Article
  • Open Access
40 Citations
7,351 Views
12 Pages

Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity

  • Stefano Palazzolo,
  • Isabella Caligiuri,
  • Andrea Augusto Sfriso,
  • Matteo Mauceri,
  • Rossella Rotondo,
  • Davide Campagnol,
  • Vincenzo Canzonieri and
  • Flavio Rizzolio

18 February 2022

Short-chain per-fluoroalkyl substances (PFAS) have replaced long-chains in many applications, however the toxicity and its mode of action and interactions due to the large number of these compounds and their mixtures is still poorly understood. The p...

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Toxics - ISSN 2305-6304