Toxics, Volume 10, Issue 3

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancer types with a limited overall survival rate due to the asymptomatic progression of symptoms in metastatic stages of the malignancy and the lack of an early reliable diagnostic bi...

Exposure to endocrine-disrupting chemicals (EDCs) contributes to substantial disease burden worldwide. We aim to quantify the disease burden and costs of EDC exposure in Canada and to compare these results with previously published findings in the Eu...

Soil health deteriorates through the contamination and remediation processes, resulting in the limitation of the reuse and recycling of the remediated soils. Therefore, soil health should be recovered for the intended purposes of reuse and recycling....

Fine particulate matter (PM), including PM_2.5 in pig houses, has received increasing attention due to the potential health risks associated with PM. At present, most studies have analyzed PM_2.5 in Chinese pig houses utilizing natural ventilation. The...

Zinc oxide nanoparticles (Nano-ZnO) have been widely used in the food, cosmetics, and biomedical fields due to their excellent antibacterial and antioxidant properties. However, with the widespread application of Nano-ZnO, Nano-ZnO inevitably enters...

Background: Occupational health hazards associated with phthalate exposure among nurses are still not well understood. Methods: We used high-performance liquid chromatography and tandem mass spectrometry to analyze phthalates. Anthropometric measurem...

A genotoxicological study was carried out on a substance-based medical device (SMD) containing anthraquinones in order to evaluate its potential mutagenic effect. The “In Vitro Mammalian Cell Micronucleus Test” was performed on human TK6...

Previous studies have described the chemical pollution in indoor air of healthcare and care facilities. From these studies, the main objective of this work was to conduct a quantitative health risk assessment of the chronic inhalation of chemical com...

Tobacco smoke-related diseases such as chronic obstructive pulmonary disease (COPD) are associated with high healthcare burden and mortality rates. Many COPD patients were reported to have muscle atrophy and weakness, with several studies suggesting...

The lower Meghna River, the easternmost part of the Ganges Delta, faces severe anthropogenic perturbations as it receives a huge discharge and industrial effluents. To measure the metal concentrations and human health hazards, edible tissues of 15 co...

An increasing burden of evidence is pointing toward pesticides as risk factors for chronic disorders such as obesity and type 2 diabetes, leading to metabolic syndrome. Our objective was to assess the impact of chlorpyrifos (CPF) on metabolic and bac...

Knowledge of spring waters’ chemical composition is paramount for both their use and their conservation. Vast surveys at the basin scale are required to define the nature and the location of the springs and to identify the hydrochemical facies of the...

Poor indoor air quality can have adverse effects on human health, especially in susceptible populations. The aim of this study was to measure the concentrations of dioxide carbon (CO₂), fine particulate matter (PM_2.5) and total volatile organic compo...

In recent years, there has been increasing concern over the environmental risks of the so called “Emerging pollutants (EPs)” that are defined as synthetic or naturally occurring chemicals that are not commonly monitored in the environment...

Electronic nicotine delivery systems (ENDS) containing synthetic nicotine have yet to be classified as tobacco products; consequently, there is ambiguity over whether Food and Drug Administration (FDA) regulatory authority can be extended to include...

Cadmium (Cd) and arsenic (As) are widely distributed pollutants that co-exist in the environment; however, their joint toxicity on living organisms is still largely unknown. In this study, we explored the joint toxicity of concurrent exposure to Cd a...

Environmental contamination by nanoparticles (NPs) and drugs represents one of the most debated issues of the last years. The aquatic biome and, indirectly, human health are strongly influenced by the negative effects induced by the widespread presen...

Pyrethroids are neurotoxicants for animals, showing a pattern of toxic action on the nervous system. Flumethrin, a synthetic pyrethroid, is used against ectoparasites in domestic animals, plants, and for public health. This compound has been shown to...

Copper oxide nanoparticles (CuO-NP) are increasingly used in consumer-related products, which may result in increased oral ingestion. Digestion of particles can change their physicochemical properties and toxicity. Therefore, our aim was to simulate...

Biodegradable mulches have become the focus of attention, as pollution caused by leftover plastic mulch material becomes increasingly severe. However, the impact of biodegradable mulches to the soil needs to be further investigated. An experiment was...

The growing increase in the world population was accompanied by a massive development of industrialization [...]

In this study the recolonization concentration concept for soil organisms is presented and validated. This concept is based on the empirically deduced avoidance–recolonization hypothesis, which shows a negative correlation between avoidance (AC...

The growing popularity of electronic cigarettes has raised several public health concerns, including the risks associated with heavy metals exposure via e-liquids and vapors. The purpose of this study was to determine, using atomic absorption spectro...

In this Special Issue, entitled “Toxic Metals, Chronic Diseases and Related Cancers”, there are 19 published manuscripts, including reports of environmental exposure monitoring [...]

In recent years, studies of heavy metal air pollution have increasingly gone beyond determining total concentrations of individual toxic metals. Chemical fractionation of potentially toxic elements in airborne particles is becoming an important part...

Humans and wildlife are exposed to endocrine-disrupting chemicals (EDCs) throughout their lives. Environmental EDCs are implicated in a range of diseases/disorders with developmental origins, including neurodevelopment and behavior. EDCs are most oft...

Insulin is the most effective glycemic-lowering drug, and for people suffering from type 1 diabetes it is a life-saving drug. Its self-dosing by patients may be associated with a higher risk of overdose, both accidental and deliberate. Insulin-induce...

An Aerosol Chemical Speciation Monitor (ACSM) was deployed to investigate the temporal variability of non-refractory particulate matter (NR-PM₁) in the coastal city of Galway, Ireland, from February to July 2016. Source apportionment of the organic a...

The present study aimed to evaluate the utility of the cement solidification process for stably disposing of waste ion exchange resin generated during the treatment of radioactive wastewater. The cement solidification process using the in-drum mixing...

In this paper, the emission sources of PM₁₀ are characterised by analysing its trace elements (TE) and ions contents. PM₁₀ samples were collected for a year (2019–2020) at five sites and analysed. PM₁₀ speciated data were analysed using graphic...

With the increasing use and release of plastic products, microplastics have rapidly accumulated in ecological environments. When microplastics enter the food chain, they cause serious harm to organisms and humans. Microplastics pollution has become a...

The discovery of biomarkers for assessing soil health requires the exploration of organisms that can explain the core functions of soil and identification of species with major roles in these functions. However, identifying specific keystone markers...

Since the National Institute of Environmental Health Sciences (NIEHS) declared conducting combined exposure research as a priority area, literature on chemical mixtures has grown dramatically. However, a systematic evaluation of the current literatur...

The Raman analysis of marijuana is challenging because of the sample’s easy photo-degradation caused by the laser intensity. In this study, optimization of collection parameters and laser focusing on marijuana trichome heads allowed collecting...

The toxic action of the Actara 25 WG insecticide (it contains 25% thiamethoxam as an active substance) in non-lethal doses was studied in two species of aquatic organisms—the Prussian carp (Carassius gibelio) and the marsh frog (Pelophylax ridi...

Soil and water pollution is a major problem that has a negative impact on ecosystems and human health in particular. In the bioremediation processes, the application of photosynthetic microorganisms, including cyanobacteria, is a direction of action...

Today, the concomitant abuse of nitrous oxide (N₂O) and illicit drugs is evident and problematic. However, there are few reports regarding the clinical manifestations of N₂O users when they present to the emergency department (ED). The purpose of thi...

The contamination of marine water bodies with petroleum hydrocarbons represents a threat to ecosystems and human health. In addition to the surface slick of crude oil, the water-soluble fraction of petroleum is responsible for the induction of severe...

Pravastatin, used for lowering cholesterol and further decreasing blood lipid, has been frequently detected in the contaminated freshwaters, whereas its long-term exposure effects on non-target aquatic invertebrates remains undetermined. Therefore, t...

For infants in the first months of life, breast milk is a complete source of nutrition; however, it can also contain elements that are harmful to the infant. It is therefore critical for infant health to characterize breast milk. The aim of this stud...

1,2-Benzisothiazolin-3-one (BIT) is a commonly used organic biocide containing an isothiazolone ring. However, it may have adverse effects on human health and its risk needs to be properly evaluated. Dermal exposure is the main route of BIT exposure,...

Polydimethylsiloxane solid-phase microextraction passive samplers were used to evaluate long-term performance of a sand/gravel cap placed in 2005 in a tidally influenced shoreline in Puget Sound to reduce polycyclic aromatic hydrocarbon (PAH) transpo...

Studies show an association between cadmium (Cd) exposure and prediabetes or type II diabetes mellitus. We have previously reported that Cd causes decreased levels of serum leptin in rats following 12 weeks of daily Cd dosing (0.6 mg/kg/b.w./day). Si...

Blooms of the toxic dinoflagellate Karenia mikimotoi could threaten the survival of marine life, and modified clay (MC) is considered a promising method for the control of harmful algal blooms. Here, using marine medaka as the model organism, the tox...

To explain losses of bees that could occur after the winter season, we studied the effects of the insecticide imidacloprid, the herbicide glyphosate and the fungicide difenoconazole, alone and in binary and ternary mixtures, on winter honey bees oral...

The increasing use of pharmaceuticals, their presence in the aquatic environment, and the associated toxic effects, have raised concerns in recent years. In this work, a new multi-residue analytical method was developed and validated for the determin...

Today, non-communicable disorders are widespread worldwide. Among them, cardiovascular diseases represent the main cause of death. At the origin of these diseases, exposure to challenges during developmental windows of vulnerability (peri-conception,...

Water is impacted by a variety of increasing pressures, such as contaminants, including genotoxic pollutants. The proposed multi-biomarker approach at a sub-individual level gives a complementary indicator to the chemical and ecological parameters of...