Hazard Assessment of Endocrine Disrupting Chemicals

Dear Colleagues,

The exponential growth in genome and transcriptome projects conducted over the past decade provides an unprecedented opportunity to informatively address the hazard assessment of endocrine-disrupting chemicals, both in invertebrate and vertebrate phyla. Several examples indisputably demonstrate that the genomic architecture of a given species is a key aspect in determining its response towards chemical insults. Therefore, disclosing the molecular landscape governing the physiological responses of different taxa is fundamental to understand the mode of action (MoA) of environmental pollutants and relate them with adversity. Understanding the MoA of environmental chemicals in a wide array of representative taxa allows for the building of a toxicant response at an ecosystem scale, thus becoming a central piece of hazard and risk assessment.

For this Topic, we invite high-quality original research papers, short communications, and reviews focusing on all aspects of hazard assessment of endocrine-disrupting chemicals. Studies may be in vivo, in vitro, and in silico studies including both field and laboratory approaches. Research on single chemicals, mixtures, and complex environmental samples are welcome. We also welcome computational or predictive studies.

Prof. Dr. Miguel Machado Santos
Dr. Davide Degli Esposti
Dr. Teresa Neuparth
Dr. Luís Filipe C. Castro
Topic Editors