Processes, Volume 9, Issue 12
2021 December - 192 articles
Cover Story: For the first time, a universally applicable and methodical approach from characterization to a PAT concept for complex mixtures is conducted. Within the QbD-based process development, a concept for PAT is necessary in risk and quality-based process design. A complex plant extract serves as an example. This study researches the potential of different PATs for online monitoring of different component groups. Based on the data, PLS models are created for the spectral data and correlations are conducted for univariate data. The prediction potential is researched. Conclusively, the results are arranged in a holistic quality-based process operation concept. View this paper. - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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