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Biomedicines, Volume 10, Issue 11

November 2022 - 329 articles

Cover Story: Specialized pro-resolving molecules (SPMs) are endogenous mediators destined to resolve inflammation. Each sub-class, resolvins, maresins, lipoxins, and protectins, has a complex temporal and functional interdependence with the rest, which brings about the resolution of inflammation through various pathways. These include the following: (1) increasing the effectiveness of efferocytosis, a process of clearing apoptotic cells; (2) reducing the levels of pro-inflammatory molecules such as MCP-1, VCAM-1, and leukotriene B4, which recruit inflammatory cells to the plaque site, increasing its size and instability. By restricting inflammation, SPMs reduce plaque size and increase its stability, leading to the prevention of life-threatening events in cardiovascular disease. View this paper
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Articles (329)

  • Review
  • Open Access
5 Citations
3,401 Views
12 Pages

A Review of the Role of Stereotactic Radiosurgery and Immunotherapy in the Management of Primary Central Nervous System Tumors

  • Eric J. Lehrer,
  • Brianna M. Jones,
  • Kunal K. Sindhu,
  • Daniel R. Dickstein,
  • Mira Cohen,
  • Stanislav Lazarev,
  • Alfredo Quiñones-Hinojosa,
  • Sheryl Green and
  • Daniel M. Trifiletti

19 November 2022

Stereotactic radiosurgery (SRS) and immune checkpoint inhibitors (ICIs) are widely used in the management of brain metastases. These therapies are commonly administered concurrently; as SRS may enhance anti-tumor immunity and responsiveness to ICIs....

  • Article
  • Open Access
1 Citations
2,567 Views
11 Pages

H19 and TUG1 lncRNAs as Novel Biomarkers for Irritable Bowel Syndrome in Diabetic Patients

  • Marwa M. Esawy,
  • Noorah Saleh Al-Sowayan,
  • Maysa A. Mobasher,
  • Amir Abd-elhameed,
  • Elsayed S. Abd elbaser,
  • Shereen A. Baioumy and
  • Marwa A. Shabana

19 November 2022

Introduction: Irritable bowel syndrome (IBS) is a gastrointestinal disorder due to enteric nervous system impairment that produces different patterns of digestion. IBS is a common finding in diabetic patients. The functions of lncRNAs in IBS are stil...

  • Article
  • Open Access
7 Citations
3,133 Views
18 Pages

Multiple Head Rotations Result in Persistent Gait Alterations in Piglets

  • Mackenzie Mull,
  • Oluwagbemisola Aderibigbe,
  • Marzieh Hajiaghamemar,
  • R. Anna Oeur and
  • Susan S Margulies

19 November 2022

Multiple/repeated mild traumatic brain injury (mTBI) in young children can cause long-term gait impairments and affect the developmental course of motor control. Using our swine model for mTBI in young children, our aim was to (i) establish a referen...

  • Article
  • Open Access
10 Citations
3,747 Views
10 Pages

The TRACK-MS Test Battery: A Very Brief Tool to Track Multiple Sclerosis-Related Cognitive Impairment

  • Daniela Taranu,
  • Hayrettin Tumani,
  • Jill Holbrook,
  • Visal Tumani,
  • Ingo Uttner and
  • Patrick Fissler

18 November 2022

Tracking cognition in patients with multiple sclerosis (MS) is important for detection of disease progression but it is often not performed in routine settings due to time constraints. This exploratory cohort study aims to develop a very brief repeat...

  • Article
  • Open Access
6 Citations
3,034 Views
11 Pages

18 November 2022

Since stroke-prone spontaneously hypertensive rats (SHRSP) develop hypertension and stroke without exception, the prevention or reduction of risk by various nutrients was tested on blood pressure and the mortality caused by stroke and cardiovascular...

  • Article
  • Open Access
7 Citations
7,184 Views
15 Pages

Antipsychotic Abuse, Dependence, and Withdrawal in the Pediatric Population: A Real-World Disproportionality Analysis

  • Diane Merino,
  • Alexandre O. Gérard,
  • Alexandre Destere,
  • Florence Askenazy,
  • Milou-Daniel Drici and
  • Susanne Thümmler

18 November 2022

Antipsychotic drugs (APs) aim to treat schizophrenia, bipolar mania, and behavioral symptoms. In child psychiatry, despite limited evidence regarding their efficacy and safety, APs are increasingly subject to off-label use. Studies investigating addi...

  • Review
  • Open Access
19 Citations
8,958 Views
19 Pages

Hidradenitis Suppurativa: The Influence of Gender, the Importance of Trigger Factors and the Implications for Patient Habits

  • Elia Rosi,
  • Maria Thais Fastame,
  • Gianmarco Silvi,
  • Prisca Guerra,
  • Giulia Nunziati,
  • Antonella Di Cesare,
  • Ilaria Scandagli,
  • Federica Ricceri and
  • Francesca Prignano

18 November 2022

Hidradenitis suppurativa (HS) is a debilitating, chronic, inflammatory skin disease primarily affecting apocrine gland-rich areas of the body. On the one hand, the presence of triggering factors—some identified, others only hypothesized—m...

  • Article
  • Open Access
4 Citations
2,532 Views
10 Pages

Evaluation of the Role of Faecal Calprotectin in the Management of Psoriatic Patients under Treatment with Biologic Drugs

  • Eugenia Veronica Di Brizzi,
  • Annachiara Rocco,
  • Graziella Babino,
  • Dario Buononato,
  • Giuseppe Argenziano and
  • Anna Balato

18 November 2022

Background: Fecal calprotectin has emerged as a significant, validated, and non-invasive biomarker allowing for the evaluation of inflammatory bowel disease. Our study assessed the reliability of the use of faecal calprotectin as a valuable tool in t...

  • Article
  • Open Access
50 Citations
5,400 Views
23 Pages

A Hybrid Workflow of Residual Convolutional Transformer Encoder for Breast Cancer Classification Using Digital X-ray Mammograms

  • Riyadh M. Al-Tam,
  • Aymen M. Al-Hejri,
  • Sachin M. Narangale,
  • Nagwan Abdel Samee,
  • Noha F. Mahmoud,
  • Mohammed A. Al-masni and
  • Mugahed A. Al-antari

18 November 2022

Breast cancer, which attacks the glandular epithelium of the breast, is the second most common kind of cancer in women after lung cancer, and it affects a significant number of people worldwide. Based on the advantages of Residual Convolutional Netwo...

  • Review
  • Open Access
30 Citations
4,145 Views
20 Pages

Role of Chemerin in Cardiovascular Diseases

  • Mirjana T. Macvanin,
  • Manfredi Rizzo,
  • Jelena Radovanovic,
  • Alper Sonmez,
  • Francesco Paneni and
  • Esma R. Isenovic

18 November 2022

(1) Background: Obesity is closely connected to the pathophysiology of cardiovascular diseases (CVDs). Excess fat accumulation is associated with metabolic malfunctions that disrupt cardiovascular homeostasis by activating inflammatory processes that...

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Biomedicines - ISSN 2227-9059