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Biomolecules, Volume 9, Issue 5
May 2019 - 44 articles
Cover Story: The prevalent endocrine disruptor, bisphenol A (BPA), was found to affect interphase and mitotic microtubule arrays in the root cells of onion and wheat. Its detrimental effects were reversible, while experiments with anti-microtubule drugs indicated that microtubule disruption was the result of a direct interaction between BPA and free tubulin submits. However, the effects of BPA differed between the two plant species. In wheat, microtubules were extensively fragmented, while in onion, annular/spiral tubulin polymers were formed, and these effects were respectively correlated with high and low tubulin acetylation. View this paper.
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Biomolecules - ISSN 2218-273X