DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM †
Institut für Pharmazeutische Chemie der Universität Wien A-1090 Wien, Althanstraße 14
*
Author to whom correspondence should be addressed.
†
Herrn em.o.Univ.Prof.Dr.Wilhelm Fleischhacker mit den besten Wünschen zum 70.Gcburtstag gewidmet
Sci. Pharm. 2001, 69(4), 315-320; https://doi.org/10.3797/scipharm.aut-01-202
Submission received: 3 September 2001
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Accepted: 4 October 2001
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Published: 28 December 2001
Abstract
Photodegradation of meloxicam is studied placing special emphasis on the investigation of the correlation between the sample concentration and the stability. For quantitation a HPTLC assay was developed. The stability indicating capability ofthe assay is proved using a sampie solution exposed to artificial irradiation from a xenon source, the peak of meloxicam was weil separated from all
degradation products. For quantitation external calibration is employed. Sample solutions of meloxicam of three different concentrations (2 mg ml-1; 250 μg ml-1 ; 40 μg ml-1) are subjected to simulated sunlight and tested for stability.
degradation products. For quantitation external calibration is employed. Sample solutions of meloxicam of three different concentrations (2 mg ml-1; 250 μg ml-1 ; 40 μg ml-1) are subjected to simulated sunlight and tested for stability.
Keywords:
meloxicam; HPTLC; densitometry; photostability
Share and Cite
MDPI and ACS Style
Bartsch, H.; Eiper, A.; Göls, B.; Kopelent-Frank, H. DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM. Sci. Pharm. 2001, 69, 315-320. https://doi.org/10.3797/scipharm.aut-01-202
AMA Style
Bartsch H, Eiper A, Göls B, Kopelent-Frank H. DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM. Scientia Pharmaceutica. 2001; 69(4):315-320. https://doi.org/10.3797/scipharm.aut-01-202
Chicago/Turabian StyleBartsch, H., A. Eiper, B. Göls, and H. Kopelent-Frank. 2001. "DENSITOMETRTSCHE UNTERSUCHUNGEN ZUR PHOTOSTABILITÄT VON MELOXICAM" Scientia Pharmaceutica 69, no. 4: 315-320. https://doi.org/10.3797/scipharm.aut-01-202
