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28 December 2001

16 Pages

KAPILLARELEKTROPHORETISCHE BESTIMMUNG VON KOHLENHYDRAT-ENANTI0MEREN †

and
Institut für Pharmazeutische Chemie Universität Wien Althanstraße 14, A-1090 Wien
*
Author to whom correspondence should be addressed.
†
Herrn cm. Univ.-Prof. Dr. W. Fleischhacker mit den besten Wünschen zum 70. Geburtstaggewidmet.

Abstract

Capillary electrophoresis is a versatile analytical technique for the determination of a very widespread range of compounds. Many applications for the separation of different pharmaceuticals, ions, herbicides and biomolecules such as DNA, proteins and peptides have been published over the last decade. A comparatively new field is the separation and determination of carbohydrates by
capillary electrophoresis, especially the assignment of absolute configuration. These methods will also gain importance in the field of pharmaceutical carbohydrate analysis. In this review a short overview ofthe different methods and separation procedures is given and some applications for the separation of sugar enantiomers are described in more detail.

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