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Biosensors, Volume 7, Issue 1

March 2017 - 14 articles

Cover Story: Chronic diseases have become one of the primary causes of death and disability worldwide. Biosensing materials that provide accurate and reliable measurement of specific biomarkers characteristic to chronic conditions could provide a tool to complement precision medicine. Here, the authors propose and demonstrate an optical sensing platform based on potentially implantable hydrogels containing bioactive microparticles that consistently respond to repeated glucose challenges. Use of specialized nanoengineered coatings on the microparticles is shown to allow tuning of the response to match the conditions of use (e.g., low or high levels of oxygen and/or glucose). View this paper
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Articles (14)

  • Article
  • Open Access
42 Citations
9,959 Views
11 Pages

13 March 2017

Metallothioneins (MTs) are a family of cysteine-rich proteins whose biological roles include the regulation of essential metal ions and protection against the harmful effects of toxic metals. Due to its high affinity for many toxic, soft metals, reco...

  • Article
  • Open Access
51 Citations
12,794 Views
13 Pages

A Urea Potentiometric Biosensor Based on a Thiophene Copolymer

  • Cheng-Yuan (Kevin) Lai,
  • Peter J. S. Foot,
  • John W. Brown and
  • Peter Spearman

3 March 2017

A potentiometric enzyme biosensor is a convenient detector for quantification of urea concentrations in industrial processes, or for monitoring patients with diabetes, kidney damage or liver malfunction. In this work, poly(3-hexylthiophene-co-3-thiop...

  • Article
  • Open Access
17 Citations
8,446 Views
9 Pages

1 March 2017

Lectins are carbohydrate-interacting proteins that play a pivotal role in multiple physiological and developmental aspects of all organisms. They can specifically interact with different bacterial and viral pathogens through carbohydrate-recognition...

  • Review
  • Open Access
29 Citations
26,481 Views
16 Pages

23 February 2017

Muscle glycogen levels have a profound impact on an athlete’s sporting performance, thus measurement is vital. Carbohydrate manipulation is a fundamental component in an athlete’s lifestyle and is a critical part of elite performance, since it can pr...

  • Article
  • Open Access
59 Citations
14,818 Views
11 Pages

19 February 2017

A single-use, in vitro biosensor for the detection of T-Tau protein in phosphate-buffer saline (PBS) and undiluted human serum was designed, manufactured, and tested. Differential pulse voltammetry (DPV) served as the transduction mechanism. This bio...

  • Review
  • Open Access
149 Citations
16,421 Views
23 Pages

Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment

  • Alessandro Sanginario,
  • Beatrice Miccoli and
  • Danilo Demarchi

15 February 2017

Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on th...

  • Communication
  • Open Access
44 Citations
11,085 Views
12 Pages

22 January 2017

There is a growing need for advanced tools that enable frequent monitoring of biomarkers for precision medicine. In this work, we present a composite hydrogel-based system providing real-time optical bioanalyte monitoring. The responsive material, al...

  • Review
  • Open Access
100 Citations
17,599 Views
21 Pages

Surface-Enhanced Raman Scattering-Based Immunoassay Technologies for Detection of Disease Biomarkers

  • Joseph Smolsky,
  • Sukhwinder Kaur,
  • Chihiro Hayashi,
  • Surinder K. Batra and
  • Alexey V. Krasnoslobodtsev

12 January 2017

Detection of biomarkers is of vital importance in disease detection, management, and monitoring of therapeutic efficacy. Extensive efforts have been devoted to the development of novel diagnostic methods that detect and quantify biomarkers with highe...

  • Article
  • Open Access
19 Citations
7,317 Views
16 Pages

5 January 2017

The capability of alternating current (AC) dielectrophoresis (DEP) for on-chip capture and chaining of the three species representative of freshwater phytoplankton was evaluated. The effects of the AC field intensity, frequency and duration on the ch...

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Biosensors - ISSN 2079-6374