Special Issue "Aptamer Sensors"
A special issue of Biosensors (ISSN 2079-6374).
Deadline for manuscript submissions: closed (31 May 2016).
Interests: conducting polymers; nanocomposite materials; electrochemical and optical biosensors; point-of-care testing (POCT); analytical chemistry
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This Special Issue will focus on recent developments in the field of aptamer sensors as these are becoming very powerful for a multitude of applications.
Aptamers are nucleic acid and peptide ligands, which can be selected for different targets starting from a huge library of molecules containing randomly created sequences. In the last years, great progress has been accomplished in the development of aptamer-based biosensors with different detection techniques. I would like to invite you to participate by submitting your original articles or reviews on your research with aptamer biosensors. Detection may include, but is not limited, to fluorescence, surface plasmon resonance, Raman, piezoelectric or electrochemical technique.
This Special Issue aims to provide a survey of the current topics and the major development lines in this rapidly growing research area.
Prof. Dr. Giovanna Marrazza
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biosensors is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- affinity binding event
- surface-enhanced Raman scattering spectroscopy
- acoustic wave
Authors: Rebeca Miranda Castro, Noemí de-los-Santos-Álvarez, Arturo J. Miranda-Ordieres, Maria Jesús Lobo-Castañón*
Affiliation: Departamento de Química-Física y Analítica. Universidad de Oviedo, Julián Clavería, 8, 33006 Oviedo (Spain); E-mail: [email protected]
Abstract: Celiac disease is a lifelong autoimmune disorder triggered by foods containing gluten, the storage protein in wheat, rye and barley. The rapidly escalating number of patients diagnosed with this disease poses a great challenge to both the food industry and regulators to guarantee food safety for all. Therefore, intensive efforts are being made to establish minimal disease-eliciting doses of gluten and, consequently, to improve gluten-free labelling. These efforts depend to a high degree on the availability of methods capable of detecting the protein in food samples at as low a level as possible. Current analytical approaches rely on the use of antibodies as selective recognition elements. With limited sensitivity, these methods exhibit some deficiencies that compromise the accuracy of the obtained results. Aptamers provide an ideal alternative for designing biosensors for fast and selective measurement of gluten in foods. This article highlights the challenges in gluten detection, current status of the use of aptamers for solving this problem, and what remains to be done to apply these systems in commercial applications.