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Biosensors, Volume 10, Issue 2

February 2020 - 7 articles

Cover Story: Ovarian cancer is associated with tumors that form in the tissue of the ovary. It is often referred to as the silent killer since early symptoms are not radically different from certain normal conditions. The disease kills many thousands of women annually. However, if detected in Stage 1, the five-year survival rate is over 90%, a fact that indicates the necessity for the development of a low-cost, screening-type assay. The present paper describes the detection of a known biomarker, lysophosphatidic acid (LPA), for the disease in serum at an early stage. The solid-phase method is based upon fluorescence measurement of labelled actin displaced by LPA from a gelsolin probe attached to silica nanoparticles. The protein, gelsolin, is a highly selective binding probe for LPA. The limit-of-detection of the assay is 5 µM in serum, which is a value close to that for detection of the Stage 1 presence of the biomarker.View this paper.
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Articles (7)

  • Article
  • Open Access
16 Citations
6,860 Views
12 Pages

Attack Graph Modeling for Implantable Pacemaker

  • Mariam Ibrahim,
  • Ahmad Alsheikh and
  • Aseel Matar

19 February 2020

Remote health monitoring systems are used to audit implantable medical devices or patients’ health in a non-clinical setting. These systems are prone to cyberattacks exploiting their critical vulnerabilities. Thus, threatening patients’ health and co...

  • Article
  • Open Access
26 Citations
6,156 Views
13 Pages

14 February 2020

Lysophosphatidic acid (LPA) is present during the medical condition of ovarian cancer at all stages of the disease, and, therefore possesses considerable potential as a biomarker for screening its presence in female patients. Unfortunately, there is...

  • Article
  • Open Access
13 Citations
6,091 Views
26 Pages

13 February 2020

The development of new C-320 electronic-nose (e-nose) methods for pre-symptomatic detection of White-Nose Syndrome (WNS) in bats has required efficacy studies of instrument capabilities to discriminate between major sources of volatile organic compou...

  • Review
  • Open Access
88 Citations
12,715 Views
22 Pages

Label-Free Biosensors for Laboratory-Based Diagnostics of Infections: Current Achievements and New Trends

  • Boris G. Andryukov,
  • Natalya N. Besednova,
  • Roman V. Romashko,
  • Tatyana S. Zaporozhets and
  • Timofey A. Efimov

12 February 2020

Infections pose a serious global public health problem and are a major cause of premature mortality worldwide. One of the most challenging objectives faced by modern medicine is timely and accurate laboratory-based diagnostics of infectious diseases....

  • Review
  • Open Access
37 Citations
7,858 Views
22 Pages

Cutting-Edge Advances in Electrochemical Affinity Biosensing at Different Molecular Level of Emerging Food Allergens and Adulterants

  • Susana Campuzano,
  • Víctor Ruiz-Valdepeñas Montiel,
  • Verónica Serafín,
  • Paloma Yáñez-Sedeño and
  • José Manuel Pingarrón

6 February 2020

The presence of allergens and adulterants in food, which represents a real threat to sensitized people and a loss of consumer confidence, is one of the main current problems facing society. The detection of allergens and adulterants in food, mainly a...

  • Feature Paper
  • Review
  • Open Access
136 Citations
18,541 Views
22 Pages

Screen-Printed Electrodes Modified with Metal Nanoparticles for Small Molecule Sensing

  • Daniel Antuña-Jiménez,
  • María Begoña González-García,
  • David Hernández-Santos and
  • Pablo Fanjul-Bolado

1 February 2020

Recent progress in the field of electroanalysis with metal nanoparticle (NP)-based screen-printed electrodes (SPEs) is discussed, focusing on the methods employed to perform the electrode surface functionalization, and the final application achieved...

  • Article
  • Open Access
15 Citations
6,194 Views
12 Pages

Newly Developed System for Acetamiprid Residue Screening in the Lettuce Samples Based on a Bioelectric Cell Biosensor

  • Theofylaktos Apostolou,
  • Konstantinos Loizou,
  • Agni Hadjilouka,
  • Antonios Inglezakis and
  • Spyridon Kintzios

24 January 2020

Population growth and increased production demands on fruit and vegetables have driven agricultural production to new heights. Nevertheless, agriculture remains one of the least optimized industries, with laboratory tests that take days to provide a...

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Biosensors - ISSN 2079-6374