Nanomaterials, Volume 10, Issue 5 (May 2020) – 193 articles
Cover Story (view full-size image): Suspended 3 × 3 × 0.5 µm3 silicon chips were fabricated with distinct physical morphologies including micrometric, micro- and nanometric, and solely nanometric features. The micro- and nanometric combination was produced by random nanowires grown on silicon. The nanometric chips were formed with self-sustaining structures of entangled nanowires. The chips were co-cultured in HeLa cells to investigate their toxicity and the effect of the morphology during cell internalization. Cell viability was demonstrated and results showed initial cell interaction with the chip nanometric features before internalization. Internalized chips with integrated nanowires may provide means of delivery into the cytosol. View this paper.
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